Véronique Hofman

The Rho GTPase activators CNF1 and DNT bacterial toxins have mucosal adjuvant properties. (2005)

Munro, Patrick, Flatau, Gilles, Anjuere, Fabienne, Hofman, Véronique, Czerkinsky, Cecil, Lemichez, Emmanuel

Cytotoxic necrotizing factor 1 (CNF1) from uropathogenic Escherichia coli belongs to a family of factors activating Rho GTPases. We report the in vivo effects of CNF1 in mice co-fed toxin and the...

Epithelial Intestinal Cell Apoptosis Induced by Helicobacter pylori Depends on Expression of the cag Pathogenicity Island Phenotype

Le'Negrate, Gaëlle, Ricci, Vittorio, Hofman, Véronique, Mograbi, Baharia, Hofman, Paul, Rossi, Bernard

Helicobacter pylori has been shown to induce chronic active gastritis and peptic ulcer and may contribute to the development of duodenal ulcer. Previous studies have shown that H. pylori mediates...

Effect of Helicobacter pylori on Polymorphonuclear Leukocyte Migration across Polarized T84 Epithelial Cell Monolayers: Role of Vacuolating Toxin VacA and cag Pathogenicity Island

Hofman, Véronique, Ricci, Vittorio, Galmiche, Antoine, Brest, Patrick, Auberger, Patrick, Rossi, Bernard, ...

Helicobacter pylori infection can induce polymorphonuclear leukocyte (PMNL) infiltration of the gastric mucosa, which characterizes acute chronic gastritis. The mechanisms underlying this process are...

Rho GTPase Is Activated by Cytotoxic Necrotizing Factor 1 in Peripheral Blood T Lymphocytes: Potential Cytotoxicity for Intestinal Epithelial Cells

Brest, Patrick, Mograbi, Baharia, Hofman, Véronique, Loubat, Agnès, Rossi, Bernard, Auberger, Patrick, ...

Some strains of Escherichia coli related to acute cystitis or colitis produce a toxin named cytotoxic necrotizing factor 1 (CNF-1). CNF-1 mediates its effects on epithelial cells or phagocytes via...

The Afa/Dr Adhesins of Diffusely Adhering Escherichia coli Stimulate Interleukin-8 Secretion, Activate Mitogen-Activated Protein Kinases, and Promote Polymorphonuclear Transepithelial Migration in T84 Polarized Epithelial Cells

Bétis, Fréderic, Brest, Patrick, Hofman, Véronique, Guignot, Julie, Bernet-Camard, Marie-Françoise, Rossi, Bernard, ...

Afa/Dr diffusely adhering Escherichia coli (Afa/Dr DAEC) strains cause symptomatic urinary tract and intestinal infections. The proinflammatory effects of Afa/Dr DAEC strains in vitro have been not...

Afa/Dr Diffusely Adhering Escherichia coli Infection in T84 Cell Monolayers Induces Increased Neutrophil Transepithelial Migration, Which in Turn Promotes Cytokine-Dependent Upregulation of Decay-Accelerating Factor (CD55), the Receptor for Afa/Dr Adhesins

Bétis, Fréderic, Brest, Patrick, Hofman, Véronique, Guignot, Julie, Kansau, Imad, Rossi, Bernard, ...

Ulcerative colitis and Crohn's disease are inflammatory bowel diseases thought to involve strains of Escherichia coli. We report here that two wild-type Afa/Dr diffusely adhering E. coli (DAEC)...

Epithelial Intestinal Cell Apoptosis Induced by Helicobacter pylori Depends on Expression of the cag Pathogenicity Island Phenotype

Le'Negrate, Gaëlle, Ricci, Vittorio, Hofman, Véronique, Mograbi, Baharia, Hofman, Paul, Rossi, Bernard

Helicobacter pylori has been shown to induce chronic active gastritis and peptic ulcer and may contribute to the development of duodenal ulcer. Previous studies have shown that H. pylori mediates...

Effect of Helicobacter pylori on Polymorphonuclear Leukocyte Migration across Polarized T84 Epithelial Cell Monolayers: Role of Vacuolating Toxin VacA and cag Pathogenicity Island

Hofman, Véronique, Ricci, Vittorio, Galmiche, Antoine, Brest, Patrick, Auberger, Patrick, Rossi, Bernard, ...

Helicobacter pylori infection can induce polymorphonuclear leukocyte (PMNL) infiltration of the gastric mucosa, which characterizes acute chronic gastritis. The mechanisms underlying this process are...

Rho GTPase Is Activated by Cytotoxic Necrotizing Factor 1 in Peripheral Blood T Lymphocytes: Potential Cytotoxicity for Intestinal Epithelial Cells

Brest, Patrick, Mograbi, Baharia, Hofman, Véronique, Loubat, Agnès, Rossi, Bernard, Auberger, Patrick, ...

Some strains of Escherichia coli related to acute cystitis or colitis produce a toxin named cytotoxic necrotizing factor 1 (CNF-1). CNF-1 mediates its effects on epithelial cells or phagocytes via...

The Afa/Dr Adhesins of Diffusely Adhering Escherichia coli Stimulate Interleukin-8 Secretion, Activate Mitogen-Activated Protein Kinases, and Promote Polymorphonuclear Transepithelial Migration in T84 Polarized Epithelial Cells

Bétis, Fréderic, Brest, Patrick, Hofman, Véronique, Guignot, Julie, Bernet-Camard, Marie-Françoise, Rossi, Bernard, ...

Afa/Dr diffusely adhering Escherichia coli (Afa/Dr DAEC) strains cause symptomatic urinary tract and intestinal infections. The proinflammatory effects of Afa/Dr DAEC strains in vitro have been not...

Afa/Dr Diffusely Adhering Escherichia coli Infection in T84 Cell Monolayers Induces Increased Neutrophil Transepithelial Migration, Which in Turn Promotes Cytokine-Dependent Upregulation of Decay-Accelerating Factor (CD55), the Receptor for Afa/Dr Adhesins

Bétis, Fréderic, Brest, Patrick, Hofman, Véronique, Guignot, Julie, Kansau, Imad, Rossi, Bernard, ...

Ulcerative colitis and Crohn's disease are inflammatory bowel diseases thought to involve strains of Escherichia coli. We report here that two wild-type Afa/Dr diffusely adhering E. coli (DAEC)...