V. A. Nierstrasz

Publication List Details

Period

1996 - 2005

Number

35

Co-Authors

In situ product removal during enzymatic cephalexin synthesis by complexation (2002)

Nierstrasz, V.A., Bosma, R., Kemperman, G.J., Strubel, M., Ooijkaas, L.P., ...

In this paper, `complexation' indicates the formation of clathrate type inclusion compounds of cephalexin with naphthalene derivatives. These inclusion compounds readily crystallise in solution,...

Integrated reactor concepts for the enzymatic kinetic synthesis of cephalexin (2002)

Nierstrasz, V.A., Bosma, R., Kroon, P.J., Tjeerdsma, P.S., DeVroom, E., ...

Integrated process concepts for enzymatic cephalexin synthesis were investigated by our group, and this article focuses on the integration of reactions and product removal during the reactions. The...

Identifying Important Parameters for a Continuous Bioscouring Process (2002)

Lenting, H.B.M., Zwier, E., Nierstrasz, V.A.

Compared to a bioscouring process in the batch mode, a continuously operating process requires relatively short processing steps. This study focusses on minimizing the required enzymatic incubation...

Modeling of the enzymatic kinetic synthesis of cephalexin -Influence of substrate concentration and temperature (2001)

Nierstrasz, V.A., Moody, H.M., Hoogschagen, M.J., Kroon, P.J., Bosma, R., ...

During enzymatic kinetic synthesis of cephalexin, an activated phenylglycine derivative (phenylglycine amide or phenylglycine methyl ester) is coupled to the nucleus 7-aminodeacetoxycephalosporanic...