V. Cleghon

Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein (2008)

Day, J.R., Cleghon, V., Houslay, M.D., Davies, S.A.

Post-translational modification by isoprenylation is a pivotal process for the correct functioning of many signalling proteins. The Drosophila melanogaster cGMP-PDE (cGMP-specific phosphodiesterase)...

Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK (1996)

Cleghon, V, Gayko, U, Copeland, TD, Perkins, LA, Perrimon, N, Morrison, DK

Isolation and characterization of a viable adenovirus mutant defective in nuclear transport of the DNA-binding protein.

Cleghon, V, Voelkerding, K, Morin, N, Delsert, C, Klessig, D F

The isolation and characterization of an adenovirus mutant, Ad5dl802r1, containing two independent deletions in the 72-kilodalton (kDa) DNA-binding protein (DBP) gene is described. The two deletions...

Introduction, stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell.

Klessig, D F, Brough, D E, Cleghon, V

The DNA-binding protein (DBP) encoded by human adenoviruses is a multifunctional polypeptide which plays a central role in regulating the expression of the viral genes. To gain a better understanding...

SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells.

Rabin, S J, Cleghon, V, Kaplan, D R

To elucidate the signal transduction mechanisms used by ligands that induce differentiation and the cessation of cell division, we utilized p13suc1-agarose, a reagent that binds p34cdc2/cdk2. By...

Isolation and characterization of a viable adenovirus mutant defective in nuclear transport of the DNA-binding protein.

Cleghon, V, Voelkerding, K, Morin, N, Delsert, C, Klessig, D F

The isolation and characterization of an adenovirus mutant, Ad5dl802r1, containing two independent deletions in the 72-kilodalton (kDa) DNA-binding protein (DBP) gene is described. The two deletions...

SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells.

Rabin, S J, Cleghon, V, Kaplan, D R

To elucidate the signal transduction mechanisms used by ligands that induce differentiation and the cessation of cell division, we utilized p13suc1-agarose, a reagent that binds p34cdc2/cdk2. By...

Introduction, stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell.

Klessig, D F, Brough, D E, Cleghon, V

The DNA-binding protein (DBP) encoded by human adenoviruses is a multifunctional polypeptide which plays a central role in regulating the expression of the viral genes. To gain a better understanding...