Ahonkhai, V I, Cherubin, C E, Sierra, M F, Bokkenheuser, V D, Shulman, M A, Mosenthal, A C
The activities of 11 antimicrobial agents against 36 strains of Campylobacter fetus subsp. jejuni were studied by a broth microdilution method. All strains were susceptible to 7 of the 11...
C-ring cleavage of flavonoids by human intestinal bacteria.
Winter, J, Moore, L H, Dowell, V R, Bokkenheuser, V D
Four hitherto undescribed Clostridium strains capable of cleaving the C ring of quercetin, kaempferol, and naringenin at C-3-C-4 were isolated from the fecal flora of humans. None of the strains...
Steroid desmolase synthesis by Eubacterium desmolans and Clostridium cadavaris.
Bokkenheuser, V D, Winter, J, Morris, G N, Locascio, S
The synthesis of a steroid desmolase was demonstrated in two obligate anaerobes: a new bacterial species, Eubacterium desmolans, isolated from cat fecal flora, and Clostridium cadavaris, recovered...
Isolation and characterization of human fecal bacteria capable of 21-dehydroxylating corticoids.
Bokkenheuser, V D, Winter, J, Dehazya, P, Kelly, W G
It has been known for a decade that human intestinal flora include organisms capable of 21-dehydroxylating corticoids. Yet the identity of the organisms synthesizing 21-dehydroxylase has remained...
New markers for Eubacterium lentum.
Bokkenheuser, V D, Winter, J, Finegold, S M, Sutter, V L, Ritchie, A E, Moore, W E, ...
Of 37 strains of Eubacterium lentum and phenotypically similar organisms, 26 (70%) synthesized a corticoid 21-dehydroxylase and/or a 3 alpha-hydroxysteroid dehydrogenase. It appeared that the...
Inactivation of contraceptive steroid hormones by human intestinal clostridia.
Bokkenheuser, V D, Winter, J, Cohen, B I, O'Rourke, S, Mosbach, E H
Steroid hormones reduced in ring-A are devoid of hormonal activity. In metabolic experiments we found that human fecal flora reduced the delta 4-3-keto structure of natural progestins to 3...
Systematic investigation of enrichment media for wild-type Campylobacter jejuni strains.
Of the media examined, thioglycolate broth supplemented with 5% lysed sheep blood, Butzler antibiotic mixture, and 0.1% lauryl sulfate was the most sensitive enrichment medium for recovery of...
Use of Directigen and acridine orange for rapid identification of human blood culture isolates.
Of 7,871 blood cultures from hospital patients, 22 yielded growth of Streptococcus pneumoniae or Haemophilus influenzae type b. The identities of 19 (86%) of these 22 strains could be verified after...
The rapid 3M Prompt inoculation system was compared with the traditional log-phase system for Autoscan identification and antibiotic susceptibility testing (MIC) of 188 recent clinical isolates. The...
Location of Campylobacter jejuni in infected chicken livers.
Barot, M S, Mosenthal, A C, Bokkenheuser, V D
To determine whether chicken livers infected with Campylobacter jejuni are seeded in vivo or contaminated after slaughtering, 117 livers purchased in retail outlets in New York were examined for...
Detection of enteric campylobacteriosis in children.
Bokkenheuser, V D, Richardson, N J, Bryner, J H, Roux, D J, Schutte, A B, Koornhof, H J, ...
Campylobacter fetus subsp. jejuni was recovered as the sole bacterial pathogen from 31% of 0- to 8-month-old children with acute gastroenteritis and from 5% of asymptomatic children (P less than...
Broiler chickens as potential source of Campylobacter infections in humans.
Grant, I H, Richardson, N J, Bokkenheuser, V D
Of 46 broiler chickens from a live poultry market in New York City, 38 (83%) harbored Campylobacter fetus subsp. jejuni in their rectal flora. The observed mean number of C. fetus per g of feces was...
Long-term infections with Campylobacter fetus subsp. jejuni.
Richardson, N J, Koornhof, H J, Bokkenheuser, V D
Seventy-three apparently healthy, rural South African schoolchildren 6 to 8 or 13 to 16 years of age were examined five times over a 16-month period for fecal pathogens. Nine were positive for...
Isolation and characterization of fecal bacteria capable of 16 alpha-dehydroxylating corticoids.
Bokkenheuser, V D, Winter, J, O'Rourke, S, Ritchie, A E
For more than a decade it has been known that the fecal flora of humans and rats includes organisms capable of 16 alpha-dehydroxylating corticoids, but their identity has remained unknown. To isolate...
Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans.
Bokkenheuser, V D, Shackleton, C H, Winter, J
Rutin and quercitrin are hydrolysed to quercetin, and robinin is hydrolysed to kaempferol, by faecal flora from healthy subjects. The enzymes required for these hydrolyses, namely alpha-rhamnosidase...
Ahonkhai, V I, Cherubin, C E, Sierra, M F, Bokkenheuser, V D, Shulman, M A, Mosenthal, A C
The activities of 11 antimicrobial agents against 36 strains of Campylobacter fetus subsp. jejuni were studied by a broth microdilution method. All strains were susceptible to 7 of the 11...
C-ring cleavage of flavonoids by human intestinal bacteria.
Winter, J, Moore, L H, Dowell, V R, Bokkenheuser, V D
Four hitherto undescribed Clostridium strains capable of cleaving the C ring of quercetin, kaempferol, and naringenin at C-3-C-4 were isolated from the fecal flora of humans. None of the strains...
Steroid desmolase synthesis by Eubacterium desmolans and Clostridium cadavaris.
Bokkenheuser, V D, Winter, J, Morris, G N, Locascio, S
The synthesis of a steroid desmolase was demonstrated in two obligate anaerobes: a new bacterial species, Eubacterium desmolans, isolated from cat fecal flora, and Clostridium cadavaris, recovered...
Isolation and characterization of human fecal bacteria capable of 21-dehydroxylating corticoids.
Bokkenheuser, V D, Winter, J, Dehazya, P, Kelly, W G
It has been known for a decade that human intestinal flora include organisms capable of 21-dehydroxylating corticoids. Yet the identity of the organisms synthesizing 21-dehydroxylase has remained...
New markers for Eubacterium lentum.
Bokkenheuser, V D, Winter, J, Finegold, S M, Sutter, V L, Ritchie, A E, Moore, W E, ...
Of 37 strains of Eubacterium lentum and phenotypically similar organisms, 26 (70%) synthesized a corticoid 21-dehydroxylase and/or a 3 alpha-hydroxysteroid dehydrogenase. It appeared that the...
Inactivation of contraceptive steroid hormones by human intestinal clostridia.
Bokkenheuser, V D, Winter, J, Cohen, B I, O'Rourke, S, Mosbach, E H
Steroid hormones reduced in ring-A are devoid of hormonal activity. In metabolic experiments we found that human fecal flora reduced the delta 4-3-keto structure of natural progestins to 3...
Systematic investigation of enrichment media for wild-type Campylobacter jejuni strains.
Of the media examined, thioglycolate broth supplemented with 5% lysed sheep blood, Butzler antibiotic mixture, and 0.1% lauryl sulfate was the most sensitive enrichment medium for recovery of...
Use of Directigen and acridine orange for rapid identification of human blood culture isolates.
Of 7,871 blood cultures from hospital patients, 22 yielded growth of Streptococcus pneumoniae or Haemophilus influenzae type b. The identities of 19 (86%) of these 22 strains could be verified after...
The rapid 3M Prompt inoculation system was compared with the traditional log-phase system for Autoscan identification and antibiotic susceptibility testing (MIC) of 188 recent clinical isolates. The...
Location of Campylobacter jejuni in infected chicken livers.
Barot, M S, Mosenthal, A C, Bokkenheuser, V D
To determine whether chicken livers infected with Campylobacter jejuni are seeded in vivo or contaminated after slaughtering, 117 livers purchased in retail outlets in New York were examined for...
Detection of enteric campylobacteriosis in children.
Bokkenheuser, V D, Richardson, N J, Bryner, J H, Roux, D J, Schutte, A B, Koornhof, H J, ...
Campylobacter fetus subsp. jejuni was recovered as the sole bacterial pathogen from 31% of 0- to 8-month-old children with acute gastroenteritis and from 5% of asymptomatic children (P less than...
Broiler chickens as potential source of Campylobacter infections in humans.
Grant, I H, Richardson, N J, Bokkenheuser, V D
Of 46 broiler chickens from a live poultry market in New York City, 38 (83%) harbored Campylobacter fetus subsp. jejuni in their rectal flora. The observed mean number of C. fetus per g of feces was...
Long-term infections with Campylobacter fetus subsp. jejuni.
Richardson, N J, Koornhof, H J, Bokkenheuser, V D
Seventy-three apparently healthy, rural South African schoolchildren 6 to 8 or 13 to 16 years of age were examined five times over a 16-month period for fecal pathogens. Nine were positive for...
Isolation and characterization of fecal bacteria capable of 16 alpha-dehydroxylating corticoids.
Bokkenheuser, V D, Winter, J, O'Rourke, S, Ritchie, A E
For more than a decade it has been known that the fecal flora of humans and rats includes organisms capable of 16 alpha-dehydroxylating corticoids, but their identity has remained unknown. To isolate...
Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans.
Bokkenheuser, V D, Shackleton, C H, Winter, J
Rutin and quercitrin are hydrolysed to quercetin, and robinin is hydrolysed to kaempferol, by faecal flora from healthy subjects. The enzymes required for these hydrolyses, namely alpha-rhamnosidase...
Age related susceptibility to Campylobacter jejuni infection in a high prevalance population.
Richardson, N J, Koornhof, H J, Bokkenheuser, V D, Mayet, Z, Rosen, E U
In a year long prospective study of diarrhoea in children under 2 years of age in Soweto, South Africa, Campylobacter jejuni was isolated in 18 of 60 children under 9 months of age with diarrhoea,...