Valérie Choesmel

Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder (2008)

Choesmel, Valérie, Fribourg, Sébastien, Aguissa-Touré, Almass-Houd, Pinaud, Noël, Legrand, Pierre, Gazda, Hanna T., ...

Diamond-Blackfan anemia (DBA) is a rare congenital disease affecting erythroid precursor differentiation. DBA is emerging as a paradigm for a new class of pathologies potentially linked to disorders...

Enrichment methods to detect bone marrow micrometastases in breast carcinoma patients: clinical relevance (2004)

Choesmel, Valérie, Pierga, Jean-Yves, Nos, Claude, Vincent-Salomon, Anne, Sigal-Zafrani, Brigitte, Thiery, Jean-Paul, ...

Abstract Introduction Improving technologies for the detection and purification of bone marrow (BM) micrometastatic cells in breast cancer patients should lead to earlier prognosis of the risk of...

The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast

Léger-Silvestre, Isabelle, Milkereit, Philipp, Ferreira-Cerca, Sébastien, Saveanu, Cosmin, Rousselle, Jean-Claude, Choesmel, Valérie, ...

We have conducted a genetic screen in order to identify ribosomal proteins of Saccharomyces cerevisiae involved in nuclear export of the small subunit precursors. This has led us to distinguish...

Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells

Rouquette, Jacques, Choesmel, Valérie, Gleizes, Pierre-Emmanuel

It is generally assumed that, in mammalian cells, preribosomal RNAs are entirely processed before nuclear exit. Here, we show that pre-40S particles exported to the cytoplasm in HeLa cells contain...

The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast

Léger-Silvestre, Isabelle, Milkereit, Philipp, Ferreira-Cerca, Sébastien, Saveanu, Cosmin, Rousselle, Jean-Claude, Choesmel, Valérie, ...

We have conducted a genetic screen in order to identify ribosomal proteins of Saccharomyces cerevisiae involved in nuclear export of the small subunit precursors. This has led us to distinguish...

Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells

Rouquette, Jacques, Choesmel, Valérie, Gleizes, Pierre-Emmanuel

It is generally assumed that, in mammalian cells, preribosomal RNAs are entirely processed before nuclear exit. Here, we show that pre-40S particles exported to the cytoplasm in HeLa cells contain...

Impaired ribosome biogenesis in Diamond-Blackfan anemia

Choesmel, Valérie, Bacqueville, Daniel, Rouquette, Jacques, Noaillac-Depeyre, Jacqueline, Fribourg, Sébastien, Crétien, Aurore, ...

The gene encoding the ribosomal protein S19 (RPS19) is frequently mutated in Diamond-Blackfan anemia (DBA), a congenital erythroblastopenia. The consequence of these mutations on the onset of the...