Monet-Leprêtre, Marie, Bardot, Boris, Lemaire, Barbara, Domenga, Valérie, Godin, Ophélia, Dichgans, Martin, ...
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an autosomal dominant small-vessel disease of the brain caused by mutations in the NOTCH3...
Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries. (2008)
Belin De Chantemèle, Eric, Retailleau, Kevin, Pinaud, Frédéric, Vessières, Emilie, Bocquet, Arnaud, Guihot, Anne-Laure, ...
OBJECTIVE: Notch3, a member of the evolutionary conserved Notch receptor family, is primarily expressed in vascular smooth muscle cells. Genetic studies in human and mice revealed a critical role for...
Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries. (2008)
Belin De Chantemèle, Eric, Retailleau, Kevin, Pinaud, Frédéric, Vessières, Emilie, Bocquet, Arnaud, Guihot, Anne-Laure, ...
OBJECTIVE: Notch3, a member of the evolutionary conserved Notch receptor family, is primarily expressed in vascular smooth muscle cells. Genetic studies in human and mice revealed a critical role for...
Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries. (2008)
Belin De Chantemèle, Eric, Retailleau, Kevin, Pinaud, Frédéric, Vessières, Emilie, Bocquet, Arnaud, Guihot, Anne-Laure, ...
OBJECTIVE: Notch3, a member of the evolutionary conserved Notch receptor family, is primarily expressed in vascular smooth muscle cells. Genetic studies in human and mice revealed a critical role for...
The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo (2007)
Monet, Marie, Domenga, Valérie, Lemaire, Barbara, Souilhol, Céline, Langa, Francina, Babinet, Charles, ...
Cerebral Autosomal Dominant Arteriopathy with Subcortical infarcts and Leukoencephalopathy (CADASIL) is the most prominent known cause of inherited stroke and vascular dementia in human adult. The...
Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy. (2005)
Dubroca, Caroline, Lacombe, Pierre, Domenga, Valérie, Maciazek, Jacqueline, Levy, Bernard, Tournier-Lasserve, Elisabeth, ...
BACKGROUND AND PURPOSE: CADASIL is an inherited small-vessel disease responsible for lacunar strokes and cognitive impairment. The disease is caused by highly stereotyped mutations in Notch3, the...
Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy. (2005)
Dubroca, Caroline, Lacombe, Pierre, Domenga, Valérie, Maciazek, Jacqueline, Levy, Bernard, Tournier-Lasserve, Elisabeth, ...
BACKGROUND AND PURPOSE: CADASIL is an inherited small-vessel disease responsible for lacunar strokes and cognitive impairment. The disease is caused by highly stereotyped mutations in Notch3, the...
Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy. (2005)
Dubroca, Caroline, Lacombe, Pierre, Domenga, Valérie, Maciazek, Jacqueline, Levy, Bernard, Tournier-Lasserve, Elisabeth, ...
BACKGROUND AND PURPOSE: CADASIL is an inherited small-vessel disease responsible for lacunar strokes and cognitive impairment. The disease is caused by highly stereotyped mutations in Notch3, the...
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells (2004)
Domenga, Valérie, Fardoux, Peggy, Lacombe, Pierre, Monet, Marie, Maciazek, Jacqueline, Krebs, Luke T., ...
Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation and...
The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients
Joutel, Anne, Andreux, Fréderic, Gaulis, Swann, Domenga, Valérie, Cecillon, Michaelle, Battail, Nicole, ...
Mutations in Notch3 cause CADASIL (cerebral autosomal dominant adult onset arteriopathy), which leads to stroke and dementia in humans. CADASIL arteriopathy is characterized by major alterations of...
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells
Domenga, Valérie, Fardoux, Peggy, Lacombe, Pierre, Monet, Marie, Maciazek, Jacqueline, Krebs, Luke T., ...
Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation and...
The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients
Joutel, Anne, Andreux, Fréderic, Gaulis, Swann, Domenga, Valérie, Cecillon, Michaelle, Battail, Nicole, ...
Mutations in Notch3 cause CADASIL (cerebral autosomal dominant adult onset arteriopathy), which leads to stroke and dementia in humans. CADASIL arteriopathy is characterized by major alterations of...
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells
Domenga, Valérie, Fardoux, Peggy, Lacombe, Pierre, Monet, Marie, Maciazek, Jacqueline, Krebs, Luke T., ...
Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation and...
Joutel, Anne, Monet, Marie, Domenga, Valérie, Riant, Florence, Tournier-Lasserve, Elisabeth
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited vascular dementia characterized by the degeneration of smooth-muscle cells in...
Ruchoux, Marie Magdeleine, Domenga, Valérie, Brulin, Peggy, Maciazek, Jacqueline, Limol, Sylvie, Tournier-Lasserve, Elisabeth, ...
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an increasingly recognized adult-onset autosomal dominant vascular dementia, caused by highly...