Valentina Fedele

Mutant huntingtin interacts with {beta}-tubulin and disrupts vesicular transport and insulin secretion (2009)

Smith, Ruben, Bacos, Karl, Fedele, Valentina, Soulet, Denis, Walz, Helena A., Obermüller, Stefanie, ...

Huntington's disease is a severe progressive neurodegenerative disorder caused by a CAG expansion in the IT15 gene, which encodes huntingtin. The disease primarily affects the neostriatum and...

Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice

Martins, L. Miguel, Morrison, Alastair, Klupsch, Kristina, Fedele, Valentina, Moisoi, Nicoleta, Teismann, Peter, ...

The serine protease HtrA2/Omi is released from the mitochondrial intermembrane space following apoptotic stimuli. Once in the cytosol, HtrA2/Omi has been implicated in promoting cell death by binding...

Evaluation of cyclin D1 expression and its subcellular distribution in mouse tissues

De Falco, Maria, Fedele, Valentina, De Luca, Luca, Penta, Roberta, Cottone, Giuliano, Cavallotti, Ivan, ...

Cyclin D1 is a key cell-cycle regulatory protein required for the cell to progress through G1 to S phase. We have shown by Western blot analysis that cyclin D1 has a wide distribution in adult mouse...

Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice

Martins, L. Miguel, Morrison, Alastair, Klupsch, Kristina, Fedele, Valentina, Moisoi, Nicoleta, Teismann, Peter, ...

The serine protease HtrA2/Omi is released from the mitochondrial intermembrane space following apoptotic stimuli. Once in the cytosol, HtrA2/Omi has been implicated in promoting cell death by binding...

Evaluation of cyclin D1 expression and its subcellular distribution in mouse tissues

De Falco, Maria, Fedele, Valentina, De Luca, Luca, Penta, Roberta, Cottone, Giuliano, Cavallotti, Ivan, ...

Cyclin D1 is a key cell-cycle regulatory protein required for the cell to progress through G1 to S phase. We have shown by Western blot analysis that cyclin D1 has a wide distribution in adult mouse...