Of mice and humans: how good are HLA transgenic mice as a model of human immune responses? (2009)
Kotturi, Maya F, Assarsson, Erika, Peters, Bjoern, Grey, Howard, Oseroff, Carla, Pasquetto, Valerie, ...
Abstract Background Previous studies have defined vaccinia virus (VACV)-derived T cell epitopes in VACV-infected human leukocyte antigen-A*0201 (HLA-A2.1) transgenic (Tg) mice and A2.1-positive human...
Protein sequence database for pathogenic arenaviruses (2007)
Bui, Huynh-Hoa, Botten, Jason, Fusseder, Nicolas, Pasquetto, Valerie, Mothe, Bianca, Buchmeier, Michael J, ...
Abstract Background Arenaviruses are a family of rodent-borne viruses that cause several hemorrhagic fevers. These diseases can be devastating and are often lethal. Herein, to aid in the design and...
Intracellular Hepatitis B Virus Nucleocapsids Survive Cytotoxic T-Lymphocyte-Induced Apoptosis†
Pasquetto, Valerie, Wieland, Stefan, Chisari, Francis V.
Following antigen recognition, hepatitis B virus (HBV)-specific cytotoxic T lymphocytes (CTL) induce a necroinflammatory liver disease in HBV-transgenic mice. An early event in this process is...
Oseroff, Carla, Kos, Ferdynand, Bui, Huynh-Hoa, Peters, Bjoern, Pasquetto, Valerie, Glenn, Jean, ...
We have analyzed by ex vivo ELISPOT the anti-vaccinia cytotoxic T lymphocyte responses of peripheral blood mononuclear cells from humans vaccinated with Dryvax vaccine. More than 6,000 peptides from...
Intracellular Hepatitis B Virus Nucleocapsids Survive Cytotoxic T-Lymphocyte-Induced Apoptosis†
Pasquetto, Valerie, Wieland, Stefan, Chisari, Francis V.
Following antigen recognition, hepatitis B virus (HBV)-specific cytotoxic T lymphocytes (CTL) induce a necroinflammatory liver disease in HBV-transgenic mice. An early event in this process is...
Oseroff, Carla, Kos, Ferdynand, Bui, Huynh-Hoa, Peters, Bjoern, Pasquetto, Valerie, Glenn, Jean, ...
We have analyzed by ex vivo ELISPOT the anti-vaccinia cytotoxic T lymphocyte responses of peripheral blood mononuclear cells from humans vaccinated with Dryvax vaccine. More than 6,000 peptides from...
Identification of Protective Lassa Virus Epitopes That Are Restricted by HLA-A2
Botten, Jason, Alexander, Jeff, Pasquetto, Valerie, Sidney, John, Barrowman, Polly, Ting, Joey, ...
Recovery from Lassa virus (LASV) infection usually precedes the appearance of neutralizing antibodies, indicating that cellular immunity plays a primary role in viral clearance. To date, the role of...
Protein sequence database for pathogenic arenaviruses
Bui, Huynh-Hoa, Botten, Jason, Fusseder, Nicolas, Pasquetto, Valerie, Mothe, Bianca, Buchmeier, Michael J, ...
Host–Virus Interactions during Malaria Infection in Hepatitis B Virus Transgenic Mice
Pasquetto, Valerie, Guidotti, Luca G., Kakimi, Kazuhiro, Tsuji, Moriya, Chisari, Francis V.
We have previously shown that hepatitis B virus (HBV) replication is abolished in the liver of HBV transgenic mice by inflammatory cytokines induced by HBV-specific cytotoxic T cells and during...
Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes
Assarsson, Erika, Greenbaum, Jason A., Sundström, Magnus, Schaffer, Lana, Hammond, Jennifer A., Pasquetto, Valerie, ...
Vaccinia virus is the prototypic orthopoxvirus and was the vaccine used to eradicate smallpox, yet the expression profiles of many of its genes remain unknown. Using a genome tiling array approach,...