Vassilis Mersinias

Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon (2009)

Bucca, Giselda, Laing, Emma, Mersinias, Vassilis, Allenby, Nicholas, Hurd, Douglas, Holdstock, Jolyon, ...

Abstract Background DNA microarrays are a key resource for global analysis of genome content, gene expression and the distribution of transcription factor binding sites. We describe the development...

Analysis of gene expression in operons of Streptomyces coelicolor (2006)

Laing, Emma, Mersinias, Vassilis, Smith, Colin P, Hubbard, Simon J

Abstract Background Recent studies have shown that microarray-derived gene-expression data are useful for operon prediction. However, it is apparent that genes within an operon do not conform to the...

Computational inference of regulator activity in a single input motif from gene expression data (2005)

Khanin, Raya, Vinciotti, Veronica, Mersinias, Vassilis, Smith, Colin, Wit, Ernst

No abstract available.

A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor (2005)

Takano, Eriko, Kinoshita, Hiroshi, Mersinias, Vassilis, Bucca, Giselda, Hotchkiss, Graham, Nihira, Takuya, ...

Gamma-butyrolactone signalling molecules are produced by many Streptomyces species, and several have been shown to regulate antibiotic production. In Streptomyces coelicolor A3(2) at least one...

BIOINFORMATICSAPPLICATIONS NOTE (2005)

Gene Expression, David Lowe, Ian T. Nabney, Vassilis Mersinias, Colin P. Smith

MILVA: An interactive tool for the exploration of multidimensional microarray data

MILVA: An interactive tool for the exploration of multidimensional microarray data (2005)

D'Alimonte, Davide, Lowe, David, Nabney, Ian T., Mersinias, Vassilis, Smith, Colin P.

Motivation: Clustering techniques such as k-means and hierarchical clustering are commonly used to analyze DNA microarray derived gene expression data. However, the interactions between processes...

MILVA: an interactive tool for the exploration of multidimensional microarray data (2005)

D'Alimonte, Davide, Lowe, David, Nabney, Ian T., Mersinias, Vassilis, Smith, Colin P.

Motivation: Clustering techniques such as k-means and hierarchical clustering are commonly used to analyze DNA microarray derived gene expression data. However, the interactions between processes...

Analysis of gene expression in operons of Streptomyces coelicolor

Laing, Emma, Mersinias, Vassilis, Smith, Colin P, Hubbard, Simon J

Analysis of the relative transcript levels of intra-operonic genes in Streptomyces coelicolor suggests significant levels of internal regulation.

Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon

Bucca, Giselda, Laing, Emma, Mersinias, Vassilis, Allenby, Nicholas, Hurd, Douglas, Holdstock, Jolyon, ...

Development of high-density microarrays for global analysis of gene expression and transcription factor binding in Streptomyces coelicolor suggests a novel role for HspR in stress adaptation.