Vera van Noort

Exploration of the omics evidence landscape: adding qualitative labels to predicted protein-protein interactions (2007)

Van Noort, Vera, Snel, Berend, Huynen, Martijn A

Abstract Background In the post-genomic era various functional genomics, proteomics and computational techniques have been developed to elucidate the protein interaction network. While some of these...

Orthology prediction at scalable resolution by phylogenetic tree analysis (2007)

Van Der Heijden, René TJM, Snel, Berend, Van Noort, Vera, Huynen, Martijn A

Abstract Background Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an...

Gene co-regulation is highly conserved in the evolution of eukaryotes and prokaryotes (2004)

Snel, Berend, Van Noort, Vera, Huynen, Martijn A.

Differences between species have been suggested to largely reside in the network of connections among the genes. Nevertheless, the rate at which these connections evolve has not been properly...

Gene co-regulation is highly conserved in the evolution of eukaryotes and prokaryotes

Snel, Berend, Van Noort, Vera, Huynen, Martijn A.

Differences between species have been suggested to largely reside in the network of connections among the genes. Nevertheless, the rate at which these connections evolve has not been properly...

The yeast coexpression network has a small-world, scale-free architecture and can be explained by a simple model

Van Noort, Vera, Snel, Berend, Huynen, Martijn A

We investigated the gene coexpression network in Saccharomyces cerevisiae, in which genes are linked when they are coregulated. This network is shown to have a scale-free, small-world architecture....

Gene co-regulation is highly conserved in the evolution of eukaryotes and prokaryotes

Snel, Berend, Van Noort, Vera, Huynen, Martijn A.

Differences between species have been suggested to largely reside in the network of connections among the genes. Nevertheless, the rate at which these connections evolve has not been properly...

The yeast coexpression network has a small-world, scale-free architecture and can be explained by a simple model

Van Noort, Vera, Snel, Berend, Huynen, Martijn A

We investigated the gene coexpression network in Saccharomyces cerevisiae, in which genes are linked when they are coregulated. This network is shown to have a scale-free, small-world architecture....

Exploration of the omics evidence landscape: adding qualitative labels to predicted protein-protein interactions

Van Noort, Vera, Snel, Berend, Huynen, Martijn A

By combining different types of large datasets that give evidence for protein-interactions, qualitative labels on the predicted protein interaction network of S. cerevisiae could be inferred,...

Comparative genomics of the Rab protein family in Apicomplexan parasites

Langsley, Gordon, Van Noort, Vera, Carret, Céline, Meissner, Markus, De Villiers, Etienne P., Bishop, Richard, ...

Rab genes encode a subgroup of small GTP-binding proteins within the ras super-family that regulate targeting and fusion of transport vesicles within the secretory and endocytic pathways. These genes...

Proteomic Profiling of Plasmodium Sporozoite Maturation Identifies New Proteins Essential for Parasite Development and Infectivity

Lasonder, Edwin, Janse, Chris J., Van Gemert, Geert-Jan, Mair, Gunnar R., Vermunt, Adriaan M. W., Douradinha, Bruno G., ...

Plasmodium falciparum sporozoites that develop and mature inside an Anopheles mosquito initiate a malaria infection in humans. Here we report the first proteomic comparison of different parasite...

Practical and theoretical advances in predicting the function of a protein by its phylogenetic distribution

Kensche, Philip R., Van Noort, Vera, Dutilh, Bas E., Huynen, Martijn A.

The gap between the amount of genome information released by genome sequencing projects and our knowledge about the proteins' functions is rapidly increasing. To fill this gap, various...