Veronika Sexl

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

Cheng, Mangeng, Sexl, Veronika, Sherr, Charles J., Roussel, Martine F.

A constitutively active form of mitogen-activated protein kinase kinase (MEK1) was synthesized under control of a zinc-inducible promoter in NIH 3T3 fibroblasts. Zinc treatment of serum-starved cells...

The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

Piekorz, Roland P., Hoffmeyer, Angelika, Duntsch, Christopher D., McKay, Catriona, Nakajima, Hideaki, Sexl, Veronika, ...

TACC3 is a centrosomal/mitotic spindle-associated protein that is highly expressed in a cell cycle-dependent manner in hematopoietic lineage cells. During embryonic development, TACC3 is expressed in...

TYK2 is a key regulator of the surveillance of B lymphoid tumors

Stoiber, Dagmar, Kovacic, Boris, Schuster, Christian, Schellack, Carola, Karaghiosoff, Marina, Kreibich, Rita, ...

Aberrant activation of the JAK-STAT pathway has been implicated in tumor formation; for example, constitutive activation of JAK2 kinase or the enforced expression of STAT5 induces leukemia in mice....

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

Cheng, Mangeng, Sexl, Veronika, Sherr, Charles J., Roussel, Martine F.

A constitutively active form of mitogen-activated protein kinase kinase (MEK1) was synthesized under control of a zinc-inducible promoter in NIH 3T3 fibroblasts. Zinc treatment of serum-starved cells...

The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

Piekorz, Roland P., Hoffmeyer, Angelika, Duntsch, Christopher D., McKay, Catriona, Nakajima, Hideaki, Sexl, Veronika, ...

TACC3 is a centrosomal/mitotic spindle-associated protein that is highly expressed in a cell cycle-dependent manner in hematopoietic lineage cells. During embryonic development, TACC3 is expressed in...

TYK2 is a key regulator of the surveillance of B lymphoid tumors

Stoiber, Dagmar, Kovacic, Boris, Schuster, Christian, Schellack, Carola, Karaghiosoff, Marina, Kreibich, Rita, ...

Aberrant activation of the JAK-STAT pathway has been implicated in tumor formation; for example, constitutive activation of JAK2 kinase or the enforced expression of STAT5 induces leukemia in mice....