Klein, Sharon, De Fougerolles, Antonin R., Blaikie, Pamela, Khan, Leila, Pepe, Angela, Green, Cynthia D., ...
GeneCalling, a genome-wide method of mRNA profiling, reveals that endothelial cells adhering to fibronectin through the α5β1 integrin, but not to laminin through the α2β1 integrin, undergo a...
Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases
Muraoka, Rebecca S., Dumont, Nancy, Ritter, Christoph A., Dugger, Teresa C., Brantley, Dana M., Chen, Jin, ...
TGF-βs are potent inhibitors of epithelial cell proliferation. However, in established carcinomas, autocrine/paracrine TGF-β interactions can enhance tumor cell viability and progression. Thus, we...
Attenuated liver fibrosis in the absence of B cells
Novobrantseva, Tatiana I., Majeau, Gerard R., Amatucci, Aldo, Kogan, Sophia, Brenner, Ian, Casola, Stefano, ...
Analysis of mononuclear cells in the adult mouse liver revealed that B cells represent as much as half of the intrahepatic lymphocyte population. Intrahepatic B cells (IHB cells) are phenotypically...
Klein, Sharon, De Fougerolles, Antonin R., Blaikie, Pamela, Khan, Leila, Pepe, Angela, Green, Cynthia D., ...
GeneCalling, a genome-wide method of mRNA profiling, reveals that endothelial cells adhering to fibronectin through the α5β1 integrin, but not to laminin through the α2β1 integrin, undergo a...
Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases
Muraoka, Rebecca S., Dumont, Nancy, Ritter, Christoph A., Dugger, Teresa C., Brantley, Dana M., Chen, Jin, ...
TGF-βs are potent inhibitors of epithelial cell proliferation. However, in established carcinomas, autocrine/paracrine TGF-β interactions can enhance tumor cell viability and progression. Thus, we...
Attenuated liver fibrosis in the absence of B cells
Novobrantseva, Tatiana I., Majeau, Gerard R., Amatucci, Aldo, Kogan, Sophia, Brenner, Ian, Casola, Stefano, ...
Analysis of mononuclear cells in the adult mouse liver revealed that B cells represent as much as half of the intrahepatic lymphocyte population. Intrahepatic B cells (IHB cells) are phenotypically...
Lee, Chun Geun, Homer, Robert J., Zhu, Zhou, Lanone, Sophie, Wang, Xiaoman, Koteliansky, Victor, ...
Interleukin (IL)-13 is a key mediator of tissue fibrosis caused by T helper cell type 2 inflammation. We hypothesized that the fibrogenic effects of IL-13 are mediated by transforming growth factor...
Frank-Kamenetsky, Maria, Grefhorst, Aldo, Anderson, Norma N., Racie, Timothy S., Bramlage, Birgit, Akinc, Akin, ...
Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates low density lipoprotein receptor (LDLR) protein levels and function. Loss of PCSK9 increases LDLR levels in liver and reduces plasma...