Primary CMV infection: a co-factor HIV-1 disease progression in African infants? (2008)
Slyker, Jennifer A, Payne, Barbara L, John-Stewart, Grace C, Obimbo, Elizabeth, Emery, Sandy, Richardson, Barbara, ...
No abstract available.
Susceptibility of porcine cytomegalovirus to antiviral drugs (2004)
Fryer, Jacqueline F. L., Griffiths, Paul D., Emery, Vincent C., Clark, Duncan A.
Objectives: Re-activation of porcine cytomegalovirus (PCMV) in the xenograft has been reported in pig-to-baboon models of xenotransplantation and is associated with invasive disease and consumptive...
Susceptibility of porcine cytomegalovirus to antiviral drugs (2004)
Fryer, Jacqueline F. L., Griffiths, Paul D., Emery, Vincent C., Clark, Duncan A.
Objectives: Re-activation of porcine cytomegalovirus (PCMV) in the xenograft has been reported in pig-to-baboon models of xenotransplantation and is associated with invasive disease and consumptive...
Lock, Matthew J., Thorley, Nicola, Teo, Jeanette, Emery, Vincent C.
Human herpesvirus 8 (HHV-8), the aetiological agent of Kaposi's sarcoma (KS), encodes many core genes that have been maintained during evolution of the Herpesviridae. Among these is a thymidine...
Emery, Vincent C., Bishop, David H.L.
A copy of the polyhedrin gene promoter of Autographa californica nuclear polyhedrosis virus (AcNPV), in association with the coding region of lymphocytic choriomeningitis virus N protein (LCMV-N) and...
Prediction of cytomegalovirus load and resistance patterns after antiviral chemotherapy
Emery, Vincent C., Griffiths, Paul D.
Cytomegalovirus (CMV) replicates rapidly in its human host with a doubling time of ≈ 1 day. Using simple mathematical models we show that the efficacy of the anti-CMV drug ganciclovir (GCV) against...
Quantitation of Porcine Cytomegalovirus in Pig Tissues by PCR
Fryer, Jacqueline F. L., Griffiths, Paul D., Fishman, Jay A., Emery, Vincent C., Clark, Duncan A.
A quantitative-competitive PCR for the quantification of porcine cytomegalovirus (PCMV) was developed. The virus was detected in a variety of pig organs (including potential xenotransplant...
Ansari, Azeem, Emery, Vincent C.
The protein encoded by the U69 open reading frame (ORF) of human herpesvirus 6 (HHV-6) has been predicted to be a protein kinase. To investigate its functional properties, we have expressed the U69...
Prediction of cytomegalovirus load and resistance patterns after antiviral chemotherapy
Emery, Vincent C., Griffiths, Paul D.
Cytomegalovirus (CMV) replicates rapidly in its human host with a doubling time of ≈ 1 day. Using simple mathematical models we show that the efficacy of the anti-CMV drug ganciclovir (GCV) against...
Quantitation of Porcine Cytomegalovirus in Pig Tissues by PCR
Fryer, Jacqueline F. L., Griffiths, Paul D., Fishman, Jay A., Emery, Vincent C., Clark, Duncan A.
A quantitative-competitive PCR for the quantification of porcine cytomegalovirus (PCMV) was developed. The virus was detected in a variety of pig organs (including potential xenotransplant...
Ansari, Azeem, Emery, Vincent C.
The protein encoded by the U69 open reading frame (ORF) of human herpesvirus 6 (HHV-6) has been predicted to be a protein kinase. To investigate its functional properties, we have expressed the U69...
Modelling cytomegalovirus replication patterns in the human host: factors important for pathogenesis
Regoes, Roland R, Frances Bowen, E, Cope, Alethea V, Gor, Dehila, Hassan-Walker, Aycan F, Grant Prentice, H, ...
Human cytomegalovirus can cause a diverse range of diseases in different immunocompromised hosts. The pathogenic mechanisms underlying these diseases have not been fully elucidated, though the...
Kinetics of Acute Hepatitis B Virus Infection in Humans
Whalley, Simon A., Murray, John M., Brown, Dave, Webster, George J.M., Emery, Vincent C., Dusheiko, Geoffrey M., ...
Using patient data from a unique single source outbreak of hepatitis B virus (HBV) infection, we have characterized the kinetics of acute HBV infection by monitoring viral turnover in the serum...
The Dynamics of Human Cytomegalovirus Replication in Vivo
Emery, Vincent C., Cope, Alethea V., Bowen, E. Frances, Gor, Dehila, Griffiths, Paul D.
Cytomegalovirus (CMV) is generally described as a slowly replicating virus. During studies of immunocompromised patients, we observed rapid changes in the quantity of CMV DNA present in serial blood...
Genotypic analysis of two hypervariable human cytomegalovirus genes
Bradley, Amanda J, Kovács, Ida J, Gatherer, Derek, Dargan, Derrick J, Alkharsah, Khaled R, Chan, Paul KS, ...
Most human cytomegalovirus (HCMV) genes are highly conserved in sequence among strains, but some exhibit a substantial degree of variation. Two of these genes are UL146, which encodes a CXC...