Vukica Srajer

7 Protein–Ligand Interaction Probed (2009)

Time-resolved Crystallography, Marius Schmidt, Hyotcherl Ihee, Reinhard Pahl, Vukica Srajer

Time-resolved (TR) crystallography is a unique method for determining the structures of intermediates in biomolecular reactions. The technique reached its mature stage with the development of the...

Allosteric action in real time: time-resolved crystallographic studies of a cooperative dimeric hemoglobin (2006)

Knapp, James E., Pahl, Reinhard, Srajer, Vukica, Royer, William E.

Protein allostery provides mechanisms for regulation of biological function at the molecular level. We present here an investigation of global, ligand-induced allosteric transition in a protein by...

Protein kinetics: Structures of intermediates and reaction mechanism from time-resolved x-ray data

Schmidt, Marius, Pahl, Reinhard, Srajer, Vukica, Anderson, Spencer, Ren, Zhong, Ihee, Hyotcherl, ...

We determine the number of authentic reaction intermediates in the later stages of the photocycle of photoactive yellow protein at room temperature, their atomic structures, and a consistent set of...

Protein kinetics: Structures of intermediates and reaction mechanism from time-resolved x-ray data

Schmidt, Marius, Pahl, Reinhard, Srajer, Vukica, Anderson, Spencer, Ren, Zhong, Ihee, Hyotcherl, ...

We determine the number of authentic reaction intermediates in the later stages of the photocycle of photoactive yellow protein at room temperature, their atomic structures, and a consistent set of...