Scientific Commons: W. Bode

Corn earworm (Helicoverpa zea), also called tomato fruitworm, is a common pest of many Solanaceous plants. This insect is known to adapt to the ingestion of plant serine protease inhibitors by using...

X-ray structure of human proMMP-1 - New insights into procollagenase activation and collagen binding (2005)

Jozic, D., Bourenkov, G., Lim, N. H., Visse, R., Nagase, H., Bode, W., ...

Mutations of the PC2 substrate binding pocket alter enzyme specificity (2005)

Kacprzak, M. M., Than, M. E., Juliano, L., Juliano, M. A., Bode, W., Lindberg, I.

Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors (2005)

Bayes, A., Comellas-Bigler, M., De La Vega, M. R., Maskos, K., Bode, W., Aviles, F. X., ...

The endoproteinase furin contains two essential Ca2+ ions stabilizing its N-terminus and the unique S1 specificity pocket (2005)

Than, M. E., Henrich, S., Bourenkov, G. P., Bartunik, H. D., Huber, R., Bode, W.

The structure of thrombin, a chameleon-like proteinase (2005)

Bode, W.

Thrombin inhibitors identified by computer-assisted multiparameter design (2005)

Riester, D., Wirsching, F., Salinas, G., Keller, M., Gebinoga, M., Kamphausen, S., ...

The NC1 dimer of human placental basement membrane collagen IV: does a covalent crosslink exist? (2005)

Than, M. E., Bourenkov, G. P., Henrich, S., Mann, K., Bode, W.

The endoproteinase furin contains two essential Ca2+ ions stabilizing its N-terminus and the unique S1 specificity pocket. (2005)

Than, M. E., Henrich, S., Bourenkov, G. P., Bartunik, H. D., Huber, R., Bode, W.

Crystal structure of the catalytic domain of MMP-16/MT3-MMP: Characterization of MT-MMP specific features (2004)

Lang, R, Braun, M, Sounni, Nor Eddine, Noël, Agnès, Frankenne, Francis, Foidart, Jean-Michel, ...

Membrane-type matrix metalloproteinases (MT-MMPs) have attracted strong attention, because four of them can activate a key player in the tumor scenario, proMMP-2/progelatinase A. In addition to this...

Cloning, expression, crystallization and initial crystallographic analysis of the C-terminal domain of the amyloid precursor protein APP (2004)

Keil, C., Huber, R., Bode, W., Than, M. E.

Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity (2004)

Reverter, D., Maskos, K., Tan, F. L., Skidgel, R. A., Bode, W.

Inhibition of furin by polyarginine-containing peptides - Nanomolar inhibition by NONA-D-arginine (2004)

Kacprzak, M. M., Peinado, J. R., Than, M. E., Appel, J., Henrich, S., Lipkind, G., ...

1.2 angstrom crystal structure of the serine carboxyl proteinase pro-kumamolisin: Structure of an intact pro-subtilase (2004)

Comellas-Bigler, M., Maskos, K., Huber, R., Oyama, H., Oda, K., Bode, W.

The staphylocoagulase family of zymogen activator and adhesion proteins (2004)

Panizzi, P., Friedrich, R., Fuentes-Prior, P., Bode, W., Bock, P. E.

Matrix metalloproteinases (2004)

Bode, W., Maskos, K.

Pharmacokinetics and tissue distribution of galantamine and galantamine-related radioactivity after single intravenous and oral administration in the rat (2004)

Van Beijsterveldt, L, Geerts, R, Verhaeghe, T, Willems, B, Bode, W, Lavrijsen, K, ...

The plasma kinetics and tissue distribution of galantamine hydrobromide [4aS-(4aalpha,6beta,8aR*)]-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro- [3a,3,2-ef] [2]benzazepin-6-ol...

Pharmacokinetics of galantamine, a cholinesterase inhibitor, in several animal species (2003)

Monbaliu, J, Verhaeghe, T, Willems, B, Bode, W, Lavrijsen, K, Meuldermans, W

In this publication, single and repeated dose experiments in rats, mice, rabbits and dogs are reported to assess the pharmacokinetics of galantamine (CAS-1953-04-4), a tertiary alkaloid with...

Properties of purified gut trypsin from Helicoverpa zea, adapted to to proteinase inhibitors. (2003)

Volpicella, M., Ceci, L.R., America, T., Gallarani, R., Bode, W., Jongsma, M.A., ...

Pest insects such as Helicoverpa spp. frequently feed on plants expressing protease inhibitors. Apparently, their digestive system can adapt to the presence of protease inhibitors. To study this, a...

Increased Biliary Excretion Of Thyroxine Glucuronide In Male Wistar Rats After Sub-chronic Treatment With The 5ht4 Agonist Prucalopride (2002)

Mannens, G., Goris, I., Laenen, A., Lampo, A., Bode, W., ...

Purpose. To investigate the effects of sub-chronic oral treatment of rats with the 5HT4 agonist prucalopride (PRU) on the elimination and biliary excretion of thyroxine (T4) and its glucuronide...

Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data (1998)

BRANDSTETTER, H., ENGH, R. A., ROEDERN, EGV., MORODER, L., HUBER, R., BODE, W., ...

Crystallization and preliminary X-ray diffraction analysis of gingipain R2 from Porphyromonas gingivalis in complex with H-D-Phe-Phe-Arg-chloromethylketone (1998)

BANBULA, A., POTEMPA, J., TRAVIS, J., BODE, W., MEDRANO, F. J.

Crystal structure of coagulogen, the clotting protein from horseshoe crab - a structural homologue of nerve growth factor (1996)

Bergner, A., Oganessyan, V., Muta, T., Iwanaga, S., Typke, D., Huber, R., ...

The clotting cascade system of the horseshoe crab (Limulus) is involved in both haemostasis and host defence, The cascade results in the conversion of coagulogen, a soluble protein, into an insoluble...

Electrostatic interactions in the association of proteins: An analysis of the thrombin-hirudin complex (1992)

KARSHIKOV, A., BODE, W., TULINSKY, A., STONE, S. R.

The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human {alpha}-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships (1992)

BODE, W., TURK, D., KARSHIKOV, A.

High-resolution crystal structure of C-Phycocyanin and polarized optical spectra of single crystals (1988)

Schirmer, T., Bode, W., Huber, R.

Effect of protein environment and the excitonic coupling on the excited-state properties of the bilinchromophores in C-Phycocyanin (1988)

Schneider, Siegfried, Scharnagl, C., Dürring, M., Schirmer, T., Bode, W.

ZZE-Configuration of chromophore ß-153 in C-phycocyanin from Mastigocladus laminosus (1987)

Schmidt, G., Siebzehnrübl, S., Fischer, R., Rüdiger, W., Scheer, Hugo, Schirmer, T., ...

Organisations- und Steuerungstechnik für Materialflußautomatisierungen (1983)

Bode, W.

W. Bode

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