Autonomic nerve stimulation reverses ventricular repolarization sequence in rabbit hearts. (2007)
Mantravadi, Rajkumar, Gabris, B., Liu, T., Choi, B.R., De Groat, W.C., Ng, G.A., ...
Axon collaterals indicate broad intraspinal role for sacral preganglionic neurons.
Morgan, C W, De Groat, W C, Felkins, L A, Zhang, S J
The classic view of preganglionic neurons in spinal autonomic nuclei is that they convey information exclusively from the central nervous system to autonomic neurons in peripheral ganglia. The...
M1 muscarinic receptor-mediated facilitation of acetylcholine release in the rat urinary bladder.
Somogyi, G T, Tanowitz, M, De Groat, W C
1. Release of [3H]ACh in response to electrical field stimulation (10 Hz) was measured in strips of rat urinary bladder and cardiac atrial tissues previously incubated with [3H]choline. 2. The volley...
Somogyi, G T, Zernova, G V, Tanowitz, M, De Groat, W C
1. 3H-Noradrenaline (NA) and 14C-acetylcholine (ACh) released by electrical field stimulation were measured simultaneously in strips from the body of rat urinary bladder. 2. omega-Conotoxin GVIA...
1. Whole-cell patch-clamp recordings in combination with axonal tracing techniques were used to investigate the effects of chronic spinal cord injury on the electrical properties of dorsal root...
Yoshimura, N, White, G, Weight, F F, De Groat, W C
1. Whole-cell patch-clamp recording in combination with axonal tracing techniques was used to examine the electrical properties of afferent neurones innervating the urinary bladder of the adult rat....
Somogyi, G T, Tanowitz, M, Zernova, G, De Groat, W C
1. [3H]Noradrenaline (NA) AND [14C]acetylcholine (ACh) released by electrical field stimulation were measured simultaneously in strips from the body of rat urinary bladder. 2. [3H]NA and [14C]ACh...
Enkephalinergic inhibition in parasympathetic ganglia of the urinary bladder of the cat.
1. Repetitive stimulation (10-20 Hz, 0.5-5 s duration) of the preganglionic nerves to ganglia on the surface of the urinary bladder of the cat produced a prolonged inhibition (duration, 30-65 s) of...
1. Experiments were undertaken to examine the mechanisms involved in the reorganization of sympathetic efferent pathways to the urinary bladder of the cat following chronic unilateral,...
The central control of the lumbar sympathetic pathway to the large intestine of the cat.
1. The origin of the lumbar sympathetic inhibitory outflow to the large intestine was studied by recording simultaneously changes in colonic motility and efferent firing in the lumbar colonic nerves...
The sacral parasympathetic reflex pathway regulating colonic motility and defaecation in the cat.
1. The sacral parasympathetic outflow to the large intestine of the cat was studied by monitoring simultaneously intestinal motility and the efferent firing in postganglionic fibres on the serosal...
1. Activation of the sympathetic input to the urinary bladder by electrical stimulation of afferent fibres in the pelvic nerve evoked three responses: (1) an initial transient rise in intravesical...
An electrophysiological study of the sacral parasympathetic pathway to the colon of the cat.
1. Electrophysiological techniques were used to study the sacral parasympathetic pathway to the colon of the cat. 2. Electrical stimulation of the sacral ventral roots or the pelvic nerve elicited...
1. In cats with the sacral dorsal roots cut on one side electrical stimulation (15-40 c/s) of the central end of the transected ipsilateral pelvic nerve depressed spontaneous bladder contractions....
Reflexes to sacral parasympathetic neurones concerned with micturition in the cat
1. Reflexes to sacral parasympathetic neurones were studied by electrophysiological techniques in decerebrate, in chloralose-anaesthetized, and in chronic spinal cats.
The identification and characteristics of sacral parasympathetic preganglionic neurones
1. Sacral parasympathetic preganglionic neurones were identified by intracellular and extracellular micro-electrode recording of antidromic potentials in response to stimulation of the pelvic nerve...
Recurrent inhibition in sacral parasympathetic pathways to the bladder
1. The effects produced by stimulation of the central end of transected ventral roots were observed on spontaneous and evoked vesical contractions and on the firing of sacral parasympathetic neurones.
Axon collaterals indicate broad intraspinal role for sacral preganglionic neurons.
Morgan, C W, De Groat, W C, Felkins, L A, Zhang, S J
The classic view of preganglionic neurons in spinal autonomic nuclei is that they convey information exclusively from the central nervous system to autonomic neurons in peripheral ganglia. The...
M1 muscarinic receptor-mediated facilitation of acetylcholine release in the rat urinary bladder.
Somogyi, G T, Tanowitz, M, De Groat, W C
1. Release of [3H]ACh in response to electrical field stimulation (10 Hz) was measured in strips of rat urinary bladder and cardiac atrial tissues previously incubated with [3H]choline. 2. The volley...
Somogyi, G T, Zernova, G V, Tanowitz, M, De Groat, W C
1. 3H-Noradrenaline (NA) and 14C-acetylcholine (ACh) released by electrical field stimulation were measured simultaneously in strips from the body of rat urinary bladder. 2. omega-Conotoxin GVIA...
1. Whole-cell patch-clamp recordings in combination with axonal tracing techniques were used to investigate the effects of chronic spinal cord injury on the electrical properties of dorsal root...
Yoshimura, N, White, G, Weight, F F, De Groat, W C
1. Whole-cell patch-clamp recording in combination with axonal tracing techniques was used to examine the electrical properties of afferent neurones innervating the urinary bladder of the adult rat....
Somogyi, G T, Tanowitz, M, Zernova, G, De Groat, W C
1. [3H]Noradrenaline (NA) AND [14C]acetylcholine (ACh) released by electrical field stimulation were measured simultaneously in strips from the body of rat urinary bladder. 2. [3H]NA and [14C]ACh...
Enkephalinergic inhibition in parasympathetic ganglia of the urinary bladder of the cat.
1. Repetitive stimulation (10-20 Hz, 0.5-5 s duration) of the preganglionic nerves to ganglia on the surface of the urinary bladder of the cat produced a prolonged inhibition (duration, 30-65 s) of...
1. Experiments were undertaken to examine the mechanisms involved in the reorganization of sympathetic efferent pathways to the urinary bladder of the cat following chronic unilateral,...
The central control of the lumbar sympathetic pathway to the large intestine of the cat.
1. The origin of the lumbar sympathetic inhibitory outflow to the large intestine was studied by recording simultaneously changes in colonic motility and efferent firing in the lumbar colonic nerves...
The sacral parasympathetic reflex pathway regulating colonic motility and defaecation in the cat.
1. The sacral parasympathetic outflow to the large intestine of the cat was studied by monitoring simultaneously intestinal motility and the efferent firing in postganglionic fibres on the serosal...
1. Activation of the sympathetic input to the urinary bladder by electrical stimulation of afferent fibres in the pelvic nerve evoked three responses: (1) an initial transient rise in intravesical...
An electrophysiological study of the sacral parasympathetic pathway to the colon of the cat.
1. Electrophysiological techniques were used to study the sacral parasympathetic pathway to the colon of the cat. 2. Electrical stimulation of the sacral ventral roots or the pelvic nerve elicited...
1. In cats with the sacral dorsal roots cut on one side electrical stimulation (15-40 c/s) of the central end of the transected ipsilateral pelvic nerve depressed spontaneous bladder contractions....
Reflexes to sacral parasympathetic neurones concerned with micturition in the cat
1. Reflexes to sacral parasympathetic neurones were studied by electrophysiological techniques in decerebrate, in chloralose-anaesthetized, and in chronic spinal cats.
The identification and characteristics of sacral parasympathetic preganglionic neurones
1. Sacral parasympathetic preganglionic neurones were identified by intracellular and extracellular micro-electrode recording of antidromic potentials in response to stimulation of the pelvic nerve...
Recurrent inhibition in sacral parasympathetic pathways to the bladder
1. The effects produced by stimulation of the central end of transected ventral roots were observed on spontaneous and evoked vesical contractions and on the firing of sacral parasympathetic neurones.
Prejunctional facilitatory alpha 1-adrenoceptors in the rat urinary bladder.
Somogyi, G T, Tanowitz, M, De Groat, W C
1. The effect of activation of alpha 1-adrenoceptors on acetylcholine (ACh) release and neurally evoked contractile responses induced by electrical field stimulation was investigated in smooth muscle...
Somogyi, G T, Zernova, G V, Yoshiyama, M, Yamamoto, T, De Groat, W C
Electrical stimulation evoked release of 3H-noradrenaline (NA) and 14C-acetylcholine (ACh), as well as neurally evoked contractions were measured at various (1–40 Hz, 100 shocks) stimulation...
Széll, E A, Yamamoto, T, De Groat, W C, Somogyi, G T
Neurally evoked contractions and release of 3H- acetylcholine (ACh) during electrical field stimulation were measured in rat urinary bladder strips.The α1 agonist phenylephrine (PE, 2–8 μM)...
Interaction between picrotoxin and 5-hydroxytryptamine in the superior cervical ganglion of the cat
De Groat, W. C., Lalley, P. M.
1. Electrophysiological techniques were utilized to study the actions of 5-hydroxytryptamine (5-HT) and picrotoxin on the superior cervical ganglion of the cat.
Yoshiyama, M., Roppolo, J. R., Thor, K. B., De Groat, W. C.
1. The effects of 3 competitive N-methyl-D-aspartate (NMDA) receptor antagonists, LY274614, LY233536 and LY235723, on the micturition reflex and external urethral sphincter EMG activity, were...