RHEUMATOID ARTHRITIS PATIENTS COPING WITHOUT DRUG THERAPY (1993)
DEIGHTON, C. M., WILLIAMSON, M. M. B., DICK, W. C.
In view of the variable and unpredictable efficacy and toxicity of non-steroidal anti-inflammatory and disease-modifying anti-rheumatic drugs, it is not surprising that some patients with rheumatoid...
PRIMARY SJOGREN'S SYNDROME IN NORTH EAST ENGLAND-A LONGITUDINAL STUDY (1991)
KELLY, C. A., FOSTER, H., PAL, B., GARDINER, P., MALCOLM, A. J., CHARLES, P., ...
We have documented the initial clinical features of 100 patients with primary Sjöigren's syndrome (SS) together with the results of their baseline investigations. The evolution of the disease in...
GENETIC MARKERS IN SJOOGREN'S SYNDROME: THE QUESTION OF ITS GENETIC HETEROGENEITY (1988)
PAPIHA, S. S., PAL, B., GRIFFITHS, I. D., ROBERTS, D. F., DICK, W. C.
Genetic factors may be implicated in the causation of Sjoögren's syndrome (SS) as shown by familial clustering of the disease and certain HLA associations. Non-HLA genetic markers in SS have not...
COBDEN, I., MATTHEWSON, K., CARR, W. P., DICK, W. C., RECORD, C. O.
The effects of acute ethanol challenge on serum glycoprotein concentrations in man were studied. Serum levels of haptoglobin, α-2-macroglobulin and pre-albumin were measured fasting and 6 hr after...
COSTS OF PROVIDING A RHEUMATOLOGICAL SERVICE (1987)
BEDI, S., CROOK, P. R., DICK, W. C., GRIFFITHS, I. D., PLATT, P. N.
As a result of a management budgeting exercise, the costs of rheumatology services in two hospitals in the Northern Region have been calculated. These comprehensive and itemized charges were derived...
PAL, B., ANDERSON, J., DICK, W. C., GRIFFITHS, I. D.
Limited joint mobility and shoulder capsulitis were evaluated in 109 consecutive diabetic patients attending an out-patient diabetic clinic. Forty-nine had insulin-dependent diabetes mellitus (IDDM)...
ATKIN, S. L., KAMEL, M., EL-BADAWY, S. A., EL-GHOBARY, A., DICK, W. C.
Patients with active Schistosonw mansoni infection attending a medical clinic in an endemic area, 100 miles from Cairo, were asked to participate in this study. Ninety-six patients are reported, 72...
Phenylbutazone Dose Response Data in Patients with Rheumatoid Arthritis (1977)
Dick, W. C., Brooks, P. M., Buchanan, W. W., Fowler, P. D.
The object of this study was to look at both objective and subjective assessments of phenylbutazone therapy in a group of patients with rheumatoid arthritis. Results of the study are reported in this...
Phenylbutazone Dose Response Data in Patients with Rheumatoid Arthritis (1977)
Dick, W. C., Brooks, P. M., Buchanan, W. W., Fowler, P. D.
The object of this study was to look at both objective and subjective assessments of phenylbutazone therapy in a group of patients with rheumatoid arthritis. Results of the study are reported in this...
Phenylbutazone Dose Response Data in Patients with Rheumatoid Arthritis (1977)
Dick, W. C., Brooks, P. M., Buchanan, W. W., Fowler, P. D.
The object of this study was to look at both objective and subjective assessments of phenylbutazone therapy in a group of patients with rheumatoid arthritis. Results of the study are reported in this...
Phenylbutazone Dose Response Data in Patients with Rheumatoid Arthritis (1977)
Dick, W. C., Brooks, P. M., Buchanan, W. W., Fowler, P. D.
The object of this study was to look at both objective and subjective assessments of phenylbutazone therapy in a group of patients with rheumatoid arthritis. Results of the study are reported in this...
Rooney, P. J., Grennan, D. P. I., Sturrock, R. D., Brooks, P. M., Dick, W. C.
A significant rise in immunoreactive gastrin in a proportion of patients with rheumatoid arthritis is confirmed. Such a rise does not seem to occur in other inflammatory or tissue destructive...
A Novel Relationship Between Plasma Kininogen and Rheumatoid Disease (1976)
Sharma, J. N., Zeitlin, I. J., Brooks, P. M., Dick, W. C.
Plasma kininogen levels in the peripheral venous blood of untreated patients with active rheumatoid disease was found to be more than twice the levels measured in healthy normal individuals or in...
Zeitlin, I.J., Sharma, J.N., Brooks, P.M., Dick, W.C.
In the aetiology of rheumatoid arthritis there is some evidence to implicate the formation of kinins in synovial fluid (Melmon, Webster, Goldfinger & Seegmiller, 1967; Keele & Eisen, 1970). The...
Rooney, P. J., Grennan, D. P. I., Sturrock, R. D., Brooks, P. M., Dick, W. C.
A significant rise in immunoreactive gastrin in a proportion of patients with rheumatoid arthritis is confirmed. Such a rise does not seem to occur in other inflammatory or tissue destructive...
Rooney, P. J., Grennan, D. P. I., Sturrock, R. D., Brooks, P. M., Dick, W. C.
A significant rise in immunoreactive gastrin in a proportion of patients with rheumatoid arthritis is confirmed. Such a rise does not seem to occur in other inflammatory or tissue destructive...
A Novel Relationship Between Plasma Kininogen and Rheumatoid Disease (1976)
Sharma, J. N., Zeitlin, I. J., Brooks, P. M., Dick, W. C.
Plasma kininogen levels in the peripheral venous blood of untreated patients with active rheumatoid disease was found to be more than twice the levels measured in healthy normal individuals or in...
Zeitlin, I.J., Sharma, J.N., Brooks, P.M., Dick, W.C.
In the aetiology of rheumatoid arthritis there is some evidence to implicate the formation of kinins in synovial fluid (Melmon, Webster, Goldfinger & Seegmiller, 1967; Keele & Eisen, 1970). The...
Rooney, P. J., Grennan, D. P. I., Sturrock, R. D., Brooks, P. M., Dick, W. C.
A significant rise in immunoreactive gastrin in a proportion of patients with rheumatoid arthritis is confirmed. Such a rise does not seem to occur in other inflammatory or tissue destructive...
A Novel Relationship Between Plasma Kininogen and Rheumatoid Disease (1976)
Sharma, J. N., Zeitlin, I. J., Brooks, P. M., Dick, W. C.
Plasma kininogen levels in the peripheral venous blood of untreated patients with active rheumatoid disease was found to be more than twice the levels measured in healthy normal individuals or in...
Zeitlin, I.J., Sharma, J.N., Brooks, P.M., Dick, W.C.
In the aetiology of rheumatoid arthritis there is some evidence to implicate the formation of kinins in synovial fluid (Melmon, Webster, Goldfinger & Seegmiller, 1967; Keele & Eisen, 1970). The...
Phenylbutazone: A Clinico-Pharmacological Study in Rheumatoid Arthritis (1975)
Brooks, P. M., Walker, J. J., Dick, W. C., Anderson, J. A., Fowler, P. D.
A clinical trial of phenylbutazone in high dose - 300 mg daily - and low dose - 50 mg daily - is presented. By analysis of the data by different methods, significant differences in clinical efficacy...
Changes in Plasma Kininogen Levels associated with Rheumatoid Arthritis (1975)
Brooks, P. M., Dick, W. C., Sharma, J. N., Zeitlin, I. J.
During a control study, it was noticed that some elderly volunteers with untreated rheumatoid inflammation has abnormally raised plasma kininogen levels. The levels are not easily explained. They may...
The Ups And Downs of Indomethacin Bioavailability (1975)
Brooks, P. M., Bell, M. A., Walker, J. J., Kennedy, A. C., Sturrock, R. D., Dick, W. C.
This paper reports results obtained during the preliminary part of a combined clinical and laboratory programme of investigation into the drug indomethacin.
Phenylbutazone: A Clinico-Pharmacological Study in Rheumatoid Arthritis (1975)
Brooks, P. M., Walker, J. J., Dick, W. C., Anderson, J. A., Fowler, P. D.
A clinical trial of phenylbutazone in high dose - 300 mg daily - and low dose - 50 mg daily - is presented. By analysis of the data by different methods, significant differences in clinical efficacy...
Changes in Plasma Kininogen Levels associated with Rheumatoid Arthritis (1975)
Brooks, P. M., Dick, W. C., Sharma, J. N., Zeitlin, I. J.
During a control study, it was noticed that some elderly volunteers with untreated rheumatoid inflammation has abnormally raised plasma kininogen levels. The levels are not easily explained. They may...
The Ups And Downs of Indomethacin Bioavailability (1975)
Brooks, P. M., Bell, M. A., Walker, J. J., Kennedy, A. C., Sturrock, R. D., Dick, W. C.
This paper reports results obtained during the preliminary part of a combined clinical and laboratory programme of investigation into the drug indomethacin.
Phenylbutazone: A Clinico-Pharmacological Study in Rheumatoid Arthritis (1975)
Brooks, P. M., Walker, J. J., Dick, W. C., Anderson, J. A., Fowler, P. D.
A clinical trial of phenylbutazone in high dose - 300 mg daily - and low dose - 50 mg daily - is presented. By analysis of the data by different methods, significant differences in clinical efficacy...
Changes in Plasma Kininogen Levels associated with Rheumatoid Arthritis (1975)
Brooks, P. M., Dick, W. C., Sharma, J. N., Zeitlin, I. J.
During a control study, it was noticed that some elderly volunteers with untreated rheumatoid inflammation has abnormally raised plasma kininogen levels. The levels are not easily explained. They may...
The Ups And Downs of Indomethacin Bioavailability (1975)
Brooks, P. M., Bell, M. A., Walker, J. J., Kennedy, A. C., Sturrock, R. D., Dick, W. C.
This paper reports results obtained during the preliminary part of a combined clinical and laboratory programme of investigation into the drug indomethacin.
The Effect of Frusemide on Indomethacin Plasma Levels (1974)
Brooks, P. M., Sturrock, R. D., Famaey, J. P., Dick, W. C.
The pharmacokinetic and clinical effects of concurrent oral indomethacin and frusemide administration were determined in eight patients with rheumatoid arthritis. Oral frusemide significantly reduces...
The Clinical Significance of Indomethacin-Probenicid Interaction (1974)
Brooks, P. M., Bell, M. A., Sturrock, R. D., Famaey, J. P., Dick, W. C.
The effect of the addition of probenecid to oral and rectal regimes of indomethacin was studied in three groups of rheumatoid arthritic patients. The addition of probenecid increases plasma levels of...
Sturrock, R. D., Watkin, C. P., Lee, P., Brooks, P. M., Dick, W. C.
The merits of intra-articular urokinase in the treatment of rheumatoid arthritis are discussed. The results of a double-blind controlled study of its use in the knee joints following intra-articular...
The Effect of Frusemide on Indomethacin Plasma Levels (1974)
Brooks, P. M., Sturrock, R. D., Famaey, J. P., Dick, W. C.
The pharmacokinetic and clinical effects of concurrent oral indomethacin and frusemide administration were determined in eight patients with rheumatoid arthritis. Oral frusemide significantly reduces...
The Clinical Significance of Indomethacin-Probenicid Interaction (1974)
Brooks, P. M., Bell, M. A., Sturrock, R. D., Famaey, J. P., Dick, W. C.
The effect of the addition of probenecid to oral and rectal regimes of indomethacin was studied in three groups of rheumatoid arthritic patients. The addition of probenecid increases plasma levels of...
Sturrock, R. D., Watkin, C. P., Lee, P., Brooks, P. M., Dick, W. C.
The merits of intra-articular urokinase in the treatment of rheumatoid arthritis are discussed. The results of a double-blind controlled study of its use in the knee joints following intra-articular...
The Effect of Frusemide on Indomethacin Plasma Levels (1974)
Brooks, P. M., Sturrock, R. D., Famaey, J. P., Dick, W. C.
The pharmacokinetic and clinical effects of concurrent oral indomethacin and frusemide administration were determined in eight patients with rheumatoid arthritis. Oral frusemide significantly reduces...
The Clinical Significance of Indomethacin-Probenicid Interaction (1974)
Brooks, P. M., Bell, M. A., Sturrock, R. D., Famaey, J. P., Dick, W. C.
The effect of the addition of probenecid to oral and rectal regimes of indomethacin was studied in three groups of rheumatoid arthritic patients. The addition of probenecid increases plasma levels of...
Sturrock, R. D., Watkin, C. P., Lee, P., Brooks, P. M., Dick, W. C.
The merits of intra-articular urokinase in the treatment of rheumatoid arthritis are discussed. The results of a double-blind controlled study of its use in the knee joints following intra-articular...
Hypergastrinaemia in rheumatoid arthritis: disease or iatrogenesis.
Rooney, J P, Vince, J, Kennedy, A C, Webb, J, Lee, P, Dick, W C, ...
Subclinical lead exposure: a possible cause of gout.
Campbell, B C, Moore, M R, Goldberg, A, Hernandez, L A, Dick, W C
Mycoplasma pneumoniae infection and arthritis in man.
Hernandez, L A, Urquhart, G E, Dick, W C
Seven patients developed arthritis after Mycoplasma pneumoniae infection. Their joint symptoms persisted for up to one year. One patient developed an articular erosion and in another rheumatoid...
Sjögren's syndrome: a contraindication to levamisole treatment?
Balint, G, El-Ghobary, A, Capell, H, Madkour, M, Dick, W C, Ferguson, M M, ...
Hypergastrinaemia in rheumatoid arthritis: disease or iatrogenesis.
Rooney, J P, Vince, J, Kennedy, A C, Webb, J, Lee, P, Dick, W C, ...
Subclinical lead exposure: a possible cause of gout.
Campbell, B C, Moore, M R, Goldberg, A, Hernandez, L A, Dick, W C
Mycoplasma pneumoniae infection and arthritis in man.
Hernandez, L A, Urquhart, G E, Dick, W C
Seven patients developed arthritis after Mycoplasma pneumoniae infection. Their joint symptoms persisted for up to one year. One patient developed an articular erosion and in another rheumatoid...
Sjögren's syndrome: a contraindication to levamisole treatment?
Balint, G, El-Ghobary, A, Capell, H, Madkour, M, Dick, W C, Ferguson, M M, ...
Otolaryngological Aspects of Sjögren's Syndrome
Doig, J. A., Whaley, K., Dick, W. C., Nuki, G., Williamson, J., Buchanan, W. W.
Twenty-two patients with Sjögren's syndrome uncomplicated by a connective tissue disorder, 31 with Sjögren's syndrome complicated by rheumatoid arthritis, and 21 with rheumatoid arthritis alone...
Grennan, D M, Bunn, C, Hughes, G R, Buchanan, W W, Dick, W C
Antibodies to the ribonucleoprotein (RNP) component of extractable nuclear antigen were measured in patients with systemic lupus erythematosus (SLE) and other connective tissue subgroups by...
On the relationship between gastrin, gastric secretion, and adjuvant arthritis in rats.
Rooney, P J, Dick, W C, Imrie, R C, Turner, D, Buchanan, K D, Ardill, J
The elevation of plasma immunoreactive gastrin known to occur during the induction of adjuvant-induced arthritis (Rooney et al., 1973) has been shown to be maximal at 7 days after injection. Gastrin...
Effects of corticosteroids and local anaesthetics applied directly to the synovial vascular bed.
De Ceulaer, K, Balint, G, El-Ghobarey, A, Dick, W C
The effects of intra-articular injection of triamcinolone hexacetonide on the rate of clearance of radioactive xenon (133Xe) was studied in 11 patients with rheumatoid arthritis. No effect of the...
Plasma zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis.
Balogh, Z, El-Ghobarey, A F, Fell, G S, Brown, D H, Dunlop, J, Dick, W C
Total plasma zinc levels in patients with rheumatoid arthritis on different therapeutic treatments were determined in conjunction with total serum proteins, serum albumin and globulin, and articular...
Walker, D J, Griffiths, M, Dewar, P, Coates, E, Dick, W C, Thompson, M, ...
A study of HLA association with rheumatoid arthritis (RA) in multicase families has been performed in north east England. Two hundred and nineteen individuals from 13 families were assessed for the...
Studies with an enthesis index as a method of clinical assessment in ankylosing spondylitis.
Mander, M, Simpson, J M, McLellan, A, Walker, D, Goodacre, J A, Dick, W C
The histopathological characteristic of ankylosing spondylitis (AS) is the presence of chronic enthesitis. Our aim was to develop a clinical measurement of the severity of tenderness over entheses....
Atkin, S L, Welbury, R R, Stanfield, E, Beavis, D, Iwais, B, Dick, W C
The results of a combined clinical and laboratory study in 55 patients throughout the leprosy spectrum are reported. Thirty one of these patients suffered from an inflammatory peripheral...
A study of headaches and migraine in Sjögren's syndrome and other rheumatic disorders.
Pal, B, Gibson, C, Passmore, J, Griffiths, I D, Dick, W C
Migraine occurs with increased frequency in patients with systemic lupus erythematosus and in subjects suffering from Raynaud's phenomenon without any underlying connective tissue disorders. A...
Clinical and laboratory studies in patients with leprosy and enthesitis.
Atkin, S L, El-Ghobarey, A, Kamel, M, Owen, J P, Dick, W C
In a combined clinical, radiological, and laboratory study of 77 patients throughout the leprosy spectrum, 10 patients had an enthesitis which has not been described previously as far as is known and...
Cellular immune mechanisms in rheumatoid arthritis and Sjögren's syndrome.
Whaley, K, Glen, A C, Deodhar, S D, Dick, W C, Nuki, G, Buchanan, W W
Radioisotope study of small joint inflammation in rheumatoid arthritis.
Collins, K E, Deodhar, S, Nuki, G, Whaley, K, Buchanan, W W, Dick, W C
Reduction in haemoglobin after knee joint surgery.
Pattison, E, Protheroe, K, Pringle, R M, Kennedy, A C, Dick, W C
Complement metabolism in the seronegative arthritides.
Whaley, K, Canesi, B, Moseley, A, Morrow, W, Sturrock, R, Mitchell, W, ...
Webb, J, Whaley, K, MacSween, R N, Nuki, G, Dick, W C, Buchanan, W W
Inter-relationships of biochemical and immunological tests of liver function have been studied in a prospective study of 216 patients with rheumatoid arthritis (RA), 32 patients with Sjogren's...
Proceedings: Ups and downs of indomethacin bioavailability.
Brooks, P M, Bell, M A, Walker, J J, Kennedy, A C, Sturrock, R D, Dick, W C
Rooney, P J, Grennan, D M, Sturrock, R D, Brooks, P M, Dick, W C
A significant rise in immunoreactive gastrin in a proportion of patients with rheumatoid arthritis is confirmed. Such a rise does not seem to occur in other inflammatory or tissue destructive...
Rooney, P J, Kennedy, A C, Gray, G H, Sturrock, R D, Buchanan, K D, Dick, W C
Serum immunoreactive gastrin is raised in some patients with rheumatoid arthritis (RA). In this paper paired samples taken within 30 minutes of each other show that this phenomenon is reproducible....
Grennan, D M, Sloane, D, Behan, A, Dick, W C
The clinical significance of antinative DNA antibodies as measured by the Farr test was investigated in 10 patients with the articular features of rheumatoid arthritis. 5 of these patients also...
Derivation of knee joint synovial perfusion. Using the Xenon (133Xe) clearance technique.
Dick, W C, Onge, R A, Gillepsie, F C, Downie, W W, Nuki, G, Gordon, I, ...
Measurement of joint inflammation. A radioisotopic method.
Dick, W C, Neufeld, R R, Prentice, A G, Woodburn, A, Whaley, K, Nuki, G, ...
Dick, W C, Neufeld, R, Grayson, M, Prentice, A, Woodburn, A, Whaley, K, ...
Indices of inflammatory activity. Relationship between isotope studies and clinical methods.
Dick, W C, Grayson, M F, Woodburn, A, Nuki, G, Buchanan, W W
Follow-up studies on synovectomy of the knee in rheumatoid arthritis.
Deodhar, S D, Downie, W W, Freeman, P A, Dick, W C, Nuki, G, Whaley, K, ...
Sympathetic control of synovial blood vessels.
Dick, W C, Porter, B, Whaley, K, Nuki, G, Downie, W W, Buchanan, W W
Measurement of synovial blood flow in normal and diseased joints.
Dick, W C, Onge, R A, Whaley, K, Gillespie, F, Boyle, J A, Jasani, M K, ...
Penicillin allergy in rheumatoid arthritis. With special reference to Sjogren's syndrome.
Williams, B O, St Onge, R A, Young, A, Nuki, G, Dick, W C, Whaley, K
Clinical and laboratory studies of arthritis in leprosy.
Atkin, S. L., El-Ghobarey, A., Kamel, M., Owen, J. P., Dick, W. C.
Arthritis associated with leprosy is underreported. In Egypt 66 patients from a leprosy colony were studied, 20 of whom had arthropathy. This was characterised by an inflammatory symmetrical...
Phenylbutazone: A Clinico-Pharmacological Study in Rheumatoid Arthritis
Brooks, P. M., Walker, J. J., Dick, W. C., Anderson, J. A., Fowler, P. D.
A clinical trial of phenylbutazone in high dose - 300 mg daily - and low dose - 50 mg daily - is presented. By analysis of the data by different methods, significant differences in clinical efficacy...
The Effect of Frusemide on Indomethacin Plasma Levels
Brooks, P. M., Sturrock, R. D., Famaey, J. P., Dick, W. C.
The pharmacokinetic and clinical effects of concurrent oral indomethacin and frusemide administration were determined in eight patients with rheumatoid arthritis. Oral frusemide significantly reduces...
Zeitlin, I.J., Sharma, J.N., Brooks, P.M., Dick, W.C.
In the aetiology of rheumatoid arthritis there is some evidence to implicate the formation of kinins in synovial fluid (Melmon, Webster, Goldfinger & Seegmiller, 1967; Keele & Eisen, 1970). The...
Phenylbutazone Dose Response Data in Patients with Rheumatoid Arthritis
Dick, W. C., Brooks, P. M., Buchanan, W. W., Fowler, P. D.
The object of this study was to look at both objective and subjective assessments of phenylbutazone therapy in a group of patients with rheumatoid arthritis. Results of the study are reported in this...
A Novel Relationship Between Plasma Kininogen and Rheumatoid Disease
Sharma, J. N., Zeitlin, I. J., Brooks, P. M., Dick, W. C.
Plasma kininogen levels in the peripheral venous blood of untreated patients with active rheumatoid disease was found to be more than twice the levels measured in healthy normal individuals or in...
Rooney, P. J., Grennan, D. P. I., Sturrock, R. D., Brooks, P. M., Dick, W. C.
A significant rise in immunoreactive gastrin in a proportion of patients with rheumatoid arthritis is confirmed. Such a rise does not seem to occur in other inflammatory or tissue destructive...
The Ups And Downs of Indomethacin Bioavailability
Brooks, P. M., Bell, M. A., Walker, J. J., Kennedy, A. C., Sturrock, R. D., Dick, W. C.
This paper reports results obtained during the preliminary part of a combined clinical and laboratory programme of investigation into the drug indomethacin.
Sturrock, R. D., Watkin, C. P., Lee, P., Brooks, P. M., Dick, W. C.
The merits of intra-articular urokinase in the treatment of rheumatoid arthritis are discussed. The results of a double-blind controlled study of its use in the knee joints following intra-articular...
Changes in Plasma Kininogen Levels associated with Rheumatoid Arthritis
Brooks, P. M., Dick, W. C., Sharma, J. N., Zeitlin, I. J.
During a control study, it was noticed that some elderly volunteers with untreated rheumatoid inflammation has abnormally raised plasma kininogen levels. The levels are not easily explained. They may...
The Clinical Significance of Indomethacin-Probenicid Interaction
Brooks, P. M., Bell, M. A., Sturrock, R. D., Famaey, J. P., Dick, W. C.
The effect of the addition of probenecid to oral and rectal regimes of indomethacin was studied in three groups of rheumatoid arthritic patients. The addition of probenecid increases plasma levels of...
Management of the dry eye in Sjogren's syndrome.
Williamson, J, Doig, W M, Forrester, J V, Tham, M H, Wilson, T, Whaley, K, ...
Histology of the lacrimal gland in keratoconjunctivitis sicca.
Williamson, J, Gibson, A A, Wilson, T, Forrester, J V, Whaley, K, Dick, W C
Froebel, K, Sturrock, R D, Dick, W C, MacSween, R N
Cellular immunity has been investigated in patients with various kinds of sero-negative arthritis. The incidence of cutaneous response to recall antigen streptokinase-streptodornase (SK-SD), and the...
Georgopoulos, K, Dick, W C, Goodacre, J A, Pain, R H
The existence of cross-reactivity between Klebsiella antigens and cells from donors who are HLA-B27 positive and exhibit ankylosing spondylitis (AS) has been reinvestigated. Cells and antisera from...
Dalakos, T. G., MacSween, R. N. M., Whaley, K., Dick, W. C., Boyle, J. A., Jasani, M. K., ...
The prevalence of rheumatoid arthritis, rheumatoid factor, antinuclear autoantibodies, thyroglobulin and thyroid `microsomal' autoantibodies and gastric parietal cell autoantibodies has been studied...
Whaley, K., Chisholm, D. M., Goudie, R. B., Downie, W. W., Dick, W. C., Boyle, J. A., ...
No correlation between the occurrence of the salivary duct antibody and focal lymphocytic sialadenitis in the labial mucosa was found in ten patients with the sicca syndrome, twenty-seven patients...
Immunological responses in Sjøgren's syndrome and rheumatoid arthriris
Whaley, K., Glen, A. C. A., MacSween, R. N. M., Deodhar, S., Dick, W. C., Nuki, G., ...
Cellular and humoral immune responses have been measured in patients with Sjøgren's syndrome with, and without, rheumatoid arthritis, patients with sero-positive and sero-negative rheumatoid...
The clinical significance of indomethacin-probenecid interaction
Brooks, P. M., Bell, M. A., Sturrock, R. D., Famaey, J. P., Dick, W. C.
1 The effect of the addition of probenecid to oral and rectal regimes of indomethacin was studied in three groups of rheumatoid arthritic patients.
The effect of frusemide on indomethacin plasma levels
Brooks, P. M., Bell, M. A., Lee, P., Rooney, P. J., Dick, W. C.
1 The pharmacokinetic and clinical effects of concurrent oral indomethacin and frusemide administration were determined in eight patients with rheumatoid arthritis.
Phenylbutazone: a clinico-pharmacological study in rheumatoid arthritis.
Brooks, P M, Walker, J J, Dick, W C
A clinical trial of phenylbutazone in high dose (300 mg daily) and low dose (50 mg daily) is presented. 2. By analysis of the data by different methods, significant differences in clinical efficacy...
Continued use of non-steroidal anti-inflammatory drugs: an index of clinical efficacy.
Rooney, P J, Capell, H A, Paterson, S, Buchanan, W W, Dick, W C
1 A double-blind entry to a trial of an active non-steroidal anti-inflammatory drug, flurbiprofen against placebo was undertaken until 100 patients with classical rheumatoid arthritis had been...
Salicylates and homoeopathy in rheumatoid arthritis: preliminary observations.
Gibson, R G, Gibson, S L, MacNeill, A D, Gray, G H, Dick, W C, Buchanan, W W
This paper reports the results of a pilot study in which 41 patients with rheumatoid arthritis were treated with high doses of salicylate, 3.9 g per day, and the results compared with a further 54...
Dick, W C, Grennan, D M, Zeitlin, I J
1 The relative effects of prostaglandins E1, E2, F1alpha, F2alpha, bradykinin, histamine and 5-hydroxytryptamine (5-HT) on the canine synovial microcirculation were investigated using the rate of...
El-Ghobarey, A., Balint, G., De Ceulaer, K., Dick, W. C., Buchanan, W. W., Hadidi, T., ...
Seven young adults, six of whom were male, all suffering from dermatomyositis unassociated with malignancy are described. These patients were not adequately controlled with high doses of...