Kok, N.F., Adang, E.M., Lind, M.Y., Hansson, B.M., Pilzecker, D., IJzermans, J.N., ...
OBJECTIVES: To determine the best approach for live donor nephrectomy to minimise discomfort to the donor and to provide good graft function. DESIGN: Single blind, randomised controlled trial....
Exhaled nitric oxide predicts asthma relapse in children with clinical asthma remission (2005)
Pijnenburg, M.W., Hofhuis, W., Hop, W.C., Jongste, J.C. De
BACKGROUND: Nitric oxide in exhaled air (FE(NO)) is a marker of eosinophilic airway inflammation. A study was undertaken to determine whether FE(NO) predicts asthma relapse in asymptomatic asthmatic...
Burger, J.W., Luijendijk, R.W., Hop, W.C., Halm, J.A., Verdaasdonk, E.G., Jeekel, J.
OBJECTIVE: The objective of this study was to determine the best treatment of incisional hernia, taking into account recurrence, complications, discomfort, cosmetic result, and patient satisfaction....
Tran, K.T., Smeenk, H.G., Eijck, C.H. Van, Kazemier, G., Hop, W.C., Greve, J.W., ...
OBJECTIVE: A prospective randomized multicenter study was performed to assess whether the results of pylorus-preserving pancreaticoduodenectomy (PPPD) equal those of the standard Whipple (SW)...
Man, R.A. De, Buuren, H.R. Van, Hop, W.C.
BACKGROUND: We studied whether the theoretical advantages of a spring-loaded liver biopsy needle exist in clinical practice and if so if they are dependent upon the experience of the physician...
Predominance of rhinovirus in the nose of symptomatic and asymptomatic infants (2003)
Benten, I.J. Van, Koopman, L.P., Niesters, B., Hop, W.C., Middelkoop, B.C. Van, Waal, L.P. De, ...
Buljevac, D., Hop, W.C., Reedeker, W., Janssens, A.C., Doorn, P.A. Van, ...
OBJECTIVE: To study the relation between self reported stressful life events not related to multiple sclerosis and the occurrence of exacerbations in relapsing-remitting multiple sclerosis. DESIGN:...
Acutely altered hemodynamics following venous obstruction in the early chick embryo (2003)
Ursem, N.T., Hop, W.C., Wladimiroff, J.W., Poelmann, R.E.
In the venous clip model specific cardiac malformations are induced in the chick embryo by obstructing the right lateral vitelline vein with a microclip. Clipping alters venous return and...
Bouwmeester, N.J., Hop, W.C., Anand, K.J., Tibboel, D.
BACKGROUND: To investigate clinical variables such as gestational age, sex, weight, the therapeutic regimens used and mechanical ventilation that might affect morphine requirements and plasma...
Janssens, H.M., Jongste, J.C. De, Hop, W.C., Tiddens, H.A.
BACKGROUND: The particles of a new hydrofluoroalkane-134a (HFA)-beclomethasone dipropionate (BDP) metered-dose inhaler (Qvar; 3M Pharmaceuticals; St. Paul, MN) are considerably smaller than those of...
Prospective study on the relationship between infections and multiple sclerosis exacerbations (2002)
Buljevac, D., Flach, H.Z., Hop, W.C., Hijdra, D., Laman, J.D., Savelkoul, H.F.J., ...
Willemse, M.J., Hop, W.C., Panzer-Grumayer, E.R., Biondi, A., Dongen, J.J. Van, Schrappe, M., ...
We performed sensitive polymerase chain reaction-based minimal residual disease (MRD) analyses on bone marrow samples at 9 follow-up time points in 71 children with T-lineage acute lymphoblastic...
Vrijland, W.W., Jeekel, H., Tseng, L.N., Eijkman, H.J., Hop, W.C., Jakimowicz, J.J., ...
OBJECTIVE: To assess the effectiveness of bioresorbable Seprafilm membrane in preventing abdominal adhesions in a prospective clinical randomized multicenter trial. SUMMARY BACKGROUND DATA: Adhesions...
Prospective study on the relationship between infections and multiple sclerosis exacerbations (2002)
Buljevac, D., Flach, H.Z., Hop, W.C., Hijdra, D., Laman, J.D., Savelkoul, H.F., ...
One of the characteristics of multiple sclerosis is the unpredictable occurrence of exacerbations and remissions. These fluctuations in disease activity are related to alterations in (auto-)immune...
Becker, M.J., Marie, S. De, Fens, M.H., Hop, W.C., Verbrugh, H.A., Bakker-Woudenberg, I.A.
In common with a proportion of patients with invasive pulmonary aspergillosis (IPA), the efficacy of AmBisome treatment regimens in our rat model remains suboptimal. To investigate whether this might...
Groof, F. De, Joosten, K.F., Janssen, J.A., Kleijn, E.D. De, Hazelzet, J.A., Hop, W.C., ...
Septic shock is the most severe clinical manifestation of meningococcal disease and is predominantly seen in children under 5 yr of age. Very limited research has been performed to elucidate the...
Berger, R.M., Cromme-Dijkhuis, A.H., Hop, W.C., Kruit, M.N., Hess, J.
BACKGROUND: Both pulmonary hypertension and pulmonary overflow are associated with functional and structural changes of the pulmonary arterial wall. Current techniques to evaluate the pulmonary...
Alers, J.C., Krijtenburg, P.J., Vis, A.N., Hoedemaeker, R.F., Wildhagen, M.F., Hop, W.C., ...
No objective parameters have been found so far that can predict the biological behavior of early stages of prostatic cancer, which are encountered frequently nowadays due to surveillance and...
Controlled low flow off line sampling of exhaled nitric oxide in children (2001)
Jobsis, Q., Raatgeep, H.C., Hop, W.C., Jongste, J.C. De
BACKGROUND: The aim of this study was to validate exhaled nitric oxide (eNO) values obtained with an alternative off line, single breath, low flow balloon sampling method against on line sampling...
Ferwerda, A., Moll, H.A., Hop, W.C., Kouwenberg, J.M., Tjon Pian Gi, C.V.
To compare the efficacy, safety and tolerability of a 3 day course of azithromycin with a 10 day course of co-amoxiclav in the treatment of children with acute lower respiratory tract infection...
Genomic alterations in malignant transformation of Barrett's esophagus (2001)
Riegman, P.H., Vissers, K.J., Alers, J.C., Geelen, E., Hop, W.C., Tilanus, H.W., ...
The incidence of adenocarcinoma in Barrett's esophagus has been increasing rapidly over the past decades. Neoplastic progression is characterized by three well-defined premalignant stages:...
Merkus, P.J., Mijnsbergen, J.Y., Hop, W.C., Jongste, J.C. De
There is a need for quick, reliable, and noninvasive lung function tests to assess airway obstruction in preschool children both for pediatric pulmonary care as well as for research purposes. We...
Jaundice in non-cirrhotic primary biliary cirrhosis: the premature ductopenic variant (2001)
Vleggaar, F.P., Buuren, H.R. Van, Zondervan, P.E., Kate, F.J. Ten, Hop, W.C.
The clinical and pathological findings of four females with primary biliary cirrhosis (PBC) with an unusual and hitherto not well recognised course are reported. Patients suffered severe pruritus and...
Jobsis, Q., Schellekens, S.L., Kroesbergen, A., Hop, W.C., Jongste, J.C. De
Measurement of nitric oxide in exhaled air is a noninvasive method to assess airway inflammation in asthma. This study was undertaken to establish the reference range of exhaled NO in healthy...
Bouwmeester, N.J., Anand, K.J., Dijk, M. Van, Hop, W.C., Boomsma, F., Tibboel, D.
Children aged 0-3 yr were stratified for age and randomized to receive either continuous morphine (CM, 10 microg x kg(-1) x h(-1)) with three-hourly placebo boluses or intermittent morphine (IM, 30...
Longitudinal survey of lymphocyte subpopulations in the first year of life (2000)
Vries, E. De, Bruin-Versteeg, S. De, Comans-Bitter, W.M., Groot, R. De, Hop, W.C., Boerma, G.J., ...
Age-matched reference values for lymphocyte subpopulations are generally obtained via cross-sectional studies, whereas patients are followed longitudinally. We performed a detailed longitudinal...
Cartilaginous airway wall dimensions and airway resistance in cystic fibrosis lungs (2000)
Tiddens, H.A., Koopman, L.P., Lambert, R.K., Elliott, W.M., Hop, W.C., ...
It is not clear how airway pathology relates to the severity of airflow obstruction and increased bronchial responsiveness in cystic fibrosis (CF) patients. The aim of this study was to measure the...
Bunt, J.E., Carnielli, V.P., Darcos Wattimena, J.L., Hop, W.C., Sauer, P.J., Zimmermann, L.J.
Most in vitro studies show that prenatal administration of corticosteroids stimulates the synthesis of surfactant phosphatidylcholine (PC), but studies in animals are controversial. Whether prenatal...
Aerosol delivery from spacers in wheezy infants: a daily life study (2000)
Janssens, H.M., Heijnen, E.M., Jong, V.M. De, Hop, W.C., Holland, W.P., Jongste, J.C. De, ...
The aims of this study were to assess and compare dose delivery and dose variability of pressurized metered dose inhalers (pMDI)/spacers in wheezy infants in daily life and to investigate factors...
Anesthesia for endobronchial laser surgery: a modified technique (1999)
Medici, G., Mallios, C., Custers, W.T., Meerbeek, J.P. Van, Verhoeven, G.T., Hop, W.C.
We describe a technique for endobronchial surgery with the neodynium:yttium-aluminum-garnet laser, in which an insufflation catheter with side holes placed into the contralateral mainstem bronchus is...
Variability of aerosol delivery via spacer devices in young asthmatic children in daily life (1999)
Janssens, H.M., Devadason, S.G., Hop, W.C., LeSouef, P.N., Jongste, J.C. De, Tiddens, H.A.
Pressurized metered dose inhalers (pMDI) are widely used together with spacers for the treatment of asthma in children. However, the variability of daily medication dose for pMDI/spacer combinations...
Compliance, hysteresis, and collapsibility of human small airways (1999)
Tiddens, H.A., Hofhuis, W., Bogaard, J.M., Hop, W.C., Bruin, H. De, Willems, L.N., ...
We tested the hypothesis that airway wall dimensions are important determinants for the mechanical properties of airways. Lung tissue was obtained from 31 smokers with different degrees of chronic...
Flow-dependency of exhaled nitric oxide in children with asthma and cystic fibrosis (1999)
Kroesbergen, A., Jobsis, Q., Bel, E.H., Hop, W.C., Jongste, J.C. De
The concentration of nitric oxide in exhaled air, a marker of airway inflammation, depends critically on the flow of exhalation. Therefore, the aim of this study was to determine the effect of...
Schipper, I., Hop, W.C., Fauser, B.C.
According to the threshold concept, FSH concentrations need to surpass a distinct level to stimulate ovarian follicle growth. The window concept stresses the significance of a limited duration of...
Hydrogen peroxide in exhaled air of healthy children: reference values (1998)
Jobsis, Q., Raatgeep, H.C., Schellekens, S.L., Hop, W.C., Hermans, P.W., Jongste, J.C. De
An increased content of hydrogen peroxide (H2O2), a marker of inflammation, has been described in the condensate of exhaled air from adults and children with inflammatory lung disorders, including...
Hazelzet, J.A., Groot, R. De, Mierlo, G. Van, Joosten, K.F., Voort, E. Van Der, Eerenberg, A., ...
To assess the relationship between capillary leakage and inflammatory mediators during sepsis, blood samples were taken on hospital admission, as well as 24 and 72 h later, from 52 children (median...
Kornelisse, R.F., Hack, C.E., Savelkoul, H.F., Hop, W.C., Mierlo, G. Van, ...
To assess the role of interleukin-12 (IL-12) and gamma interferon (IFN-gamma) in children with bacterial meningitis, bioactive IL-12 (p70) and the inactive subunit p40 and IFN-gamma were measured in...
Foreign material in postoperative adhesions (1996)
Luijendijk, R.W., Lange, D.C. De, Wauters, C.C., Hop, W.C., Duron, J.J., Pailler, J.L., ...
OBJECTIVE: The authors determined the prevalence of foreign body granulomas in intra-abdominal adhesions in patients with a history of abdominal surgery. PATIENTS AND METHODS: In a cross-sectional,...
Tiddens, H.A., Bogaard, J.M., Jongste, J.C. De, Hop, W.C., Coxson, H.O., Pare, P.D.
Maximal expiratory flow in chronic obstructive pulmonary disease (COPD) could be reduced by three different mechanisms; loss of lung elastic recoil, decreased airway conductance upstream of...
Luiten, E.J., Hop, W.C., Lange, J.F., Bruining, H.A.
OBJECTIVE: A randomized, controlled, multicenter trial was undertaken in 102 patients with objective evidence of severe acute pancreatitis to evaluate whether selective decontamination reduces...
Busch, O.R., Hop, W.C., Marquet, R.L., Jeekel, J.
OBJECTIVE. The authors analyzed the effect of blood transfusions on the pattern of colorectal cancer recurrence. BACKGROUND. Retrospective studies suggest that blood transfusions are associated with...
Intrathecal production of interleukin-12 and gamma interferon in patients with bacterial meningitis.
Kornelisse, R F, Hack, C E, Savelkoul, H F, Hop, W C, Van Mierlo, G, ...
To assess the role of interleukin-12 (IL-12) and gamma interferon (IFN-gamma) in children with bacterial meningitis, bioactive IL-12 (p70) and the inactive subunit p40 and IFN-gamma were measured in...
Diagnostic value of anti-Candida enolase antibodies.
Van Deventer, A J, Van Vliet, H J, Hop, W C, Goessens, W H
An immunodominant antigen with enolase enzyme activity was purified and used for the development of an assay to detect antibodies directed against this antigen in sera from patients with either...
Van Deventer, A J, Van Vliet, H J, Voogd, L, Hop, W C, Goessens, W H
In this study, it was shown that the diagnostic accuracy of antibody detection by a counterimmunoelectrophoresis technique could be improved by using cytoplasmic antigens depleted of mannan residues....
Luijendijk, R W, Jeekel, J, Storm, R K, Schutte, P J, Hop, W C, Drogendijk, A C, ...
OBJECTIVE: The authors determined the prevalence of incisional hernia and nerve entrapment in patients with a low transverse Pfannenstiel incision. SUMMARY BACKGROUND DATA: The literature on the...
Busch, O R, Hop, W C, Marquet, R L, Jeekel, J
OBJECTIVE. The authors analyzed the effect of blood transfusions on the pattern of colorectal cancer recurrence. BACKGROUND. Retrospective studies suggest that blood transfusions are associated with...
Luiten, E J, Hop, W C, Lange, J F, Bruining, H A
OBJECTIVE: A randomized, controlled, multicenter trial was undertaken in 102 patients with objective evidence of severe acute pancreatitis to evaluate whether selective decontamination reduces...
Foreign material in postoperative adhesions.
Luijendijk, R W, De Lange, D C, Wauters, C C, Hop, W C, Duron, J J, Pailler, J L, ...
OBJECTIVE: The authors determined the prevalence of foreign body granulomas in intra-abdominal adhesions in patients with a history of abdominal surgery. PATIENTS AND METHODS: In a cross-sectional,...
Klinkenbijl, J H, Van Der Schelling, G P, Hop, W C, Van Pel, R, Bruining, H A, Jeekel, J
The aim of this study was to establish whether the pylorus-preserving pancreatoduodenectomy (PPPD) is a safe and radical procedure in malignant disease of the head of the pancreas and periampullary...
Intrathecal production of interleukin-12 and gamma interferon in patients with bacterial meningitis.
Kornelisse, R F, Hack, C E, Savelkoul, H F, Hop, W C, Van Mierlo, G, ...
To assess the role of interleukin-12 (IL-12) and gamma interferon (IFN-gamma) in children with bacterial meningitis, bioactive IL-12 (p70) and the inactive subunit p40 and IFN-gamma were measured in...
Diagnostic value of anti-Candida enolase antibodies.
Van Deventer, A J, Van Vliet, H J, Hop, W C, Goessens, W H
An immunodominant antigen with enolase enzyme activity was purified and used for the development of an assay to detect antibodies directed against this antigen in sera from patients with either...
Van Deventer, A J, Van Vliet, H J, Voogd, L, Hop, W C, Goessens, W H
In this study, it was shown that the diagnostic accuracy of antibody detection by a counterimmunoelectrophoresis technique could be improved by using cytoplasmic antigens depleted of mannan residues....
Luijendijk, R W, Jeekel, J, Storm, R K, Schutte, P J, Hop, W C, Drogendijk, A C, ...
OBJECTIVE: The authors determined the prevalence of incisional hernia and nerve entrapment in patients with a low transverse Pfannenstiel incision. SUMMARY BACKGROUND DATA: The literature on the...
Busch, O R, Hop, W C, Marquet, R L, Jeekel, J
OBJECTIVE. The authors analyzed the effect of blood transfusions on the pattern of colorectal cancer recurrence. BACKGROUND. Retrospective studies suggest that blood transfusions are associated with...
Luiten, E J, Hop, W C, Lange, J F, Bruining, H A
OBJECTIVE: A randomized, controlled, multicenter trial was undertaken in 102 patients with objective evidence of severe acute pancreatitis to evaluate whether selective decontamination reduces...
Foreign material in postoperative adhesions.
Luijendijk, R W, De Lange, D C, Wauters, C C, Hop, W C, Duron, J J, Pailler, J L, ...
OBJECTIVE: The authors determined the prevalence of foreign body granulomas in intra-abdominal adhesions in patients with a history of abdominal surgery. PATIENTS AND METHODS: In a cross-sectional,...
Klinkenbijl, J H, Van Der Schelling, G P, Hop, W C, Van Pel, R, Bruining, H A, Jeekel, J
The aim of this study was to establish whether the pylorus-preserving pancreatoduodenectomy (PPPD) is a safe and radical procedure in malignant disease of the head of the pancreas and periampullary...
Achalasia complicated by oesophageal squamous cell carcinoma: a prospective study in 195 patients.
Meijssen, M A, Tilanus, H W, Van Blankenstein, M, Hop, W C, Ong, G L
To determine the incidence of oesophageal carcinoma in patients with achalasia and to establish the efficacy of endoscopic surveillance, 195 consecutive patients with achalasia (90 men and 105 women,...
Menke-Pluymers, M B, Mulder, A H, Hop, W C, Van Blankenstein, M, Tilanus, H W
The role of dysplasia and aneuploidy as markers in columnar epithelium for malignant degeneration in Barrett's oesophagus was compared in a case control study comprising 38 patients with benign...
Outcome of surgical treatment of adenocarcinoma in Barrett's oesophagus.
Menke-Pluymers, M B, Schoute, N W, Mulder, A H, Hop, W C, Van Blankenstein, M, Tilanus, H W
A retrospective study was performed of an 11 year period (1978-88) to analyse the survival of 112 patients (85 men and 27 women, mean age 63 years) with adenocarcinoma in a columnar lined (Barrett's)...
Oesophageal cancer is an uncommon cause of death in patients with Barrett's oesophagus.
Dees, J, Hop, W C, Van Blankenstein, M
BACKGROUND: Barrett's oesophagus carries a 30-fold to 40-fold increased risk of oesophageal cancer. It is unknown whether endoscopic surveillance programmes reduce mortality from oesophageal cancer....
Van Den Anker, J N, Hop, W C, Schoemaker, R C, Van Der Heijden, B J, Neijens, H J, De Groot, R
1. The effects of postnatal age and postnatal exposure to indomethacin on the pharmacokinetic parameters of ceftazidime (CAZ) were investigated in 23 preterm infants (gestational age 28.7 +/- 1.7...
Birnie, D, Thoe Schwartzenberg, G W, Hop, W C, Kerrebijn, K F
As minute volume increases with age, a study was carried out to determine whether the measurement of bronchial responsiveness to pharmacological agents with the tidal breathing technique in children...
Protein restriction in chronic renal failure.
Nauta, J, Hop, W C, De Jong, M C, Reitsma-Bierens, W C, Ploos Van Amstel, S L, ...
The aim of the study was to investigate the effect of a protein restricted diet on renal function and growth of children with chronic renal failure. In a multicentre prospective study 56 children...
Changes in long term prognosis for breast cancer in a Dutch cancer registry.
Nab, H. W., Hop, W. C., Crommelin, M. A., Kluck, H. M., Van Der Heijden, L. H., Coebergh, J. W.
OBJECTIVES--To assess whether the long term survival of patients with breast cancer has changed with time. DESIGN--Population based descriptive study. SETTING--Eindhoven Cancer Registry in south east...
Improved prognosis of breast cancer since 1970 in south-eastern Netherlands.
Nab, H. W., Hop, W. C., Crommelin, M. A., Kluck, H. M., Coebergh, J. W.
Despite many new advances in breast cancer therapy since the 1970s, there are only few reports on improved prognosis in a general population. A follow-up of more than 10 years is rarely reported, and...