W. Chao

Publication List Details

Period

1998 - 2008

Number

33

Co-Authors

Advanced Single Flux Quantum Devices (1998)

Likharev, Konstantin K., Bunyk, P., Chao, W., Filippov, T., Kameda, Y.

The goal of the present effort is the further development of ultrafast "Rapid Single-Flux-Quantum"(RSFQ) devices and circuits based on the storage, transfer, and processing of digital bits encoded by...

Inhibitory effect of porcine surfactant on the respiratory burst oxidase in human neutrophils. Attenuation of p47phox and p67phox membrane translocation as the mechanism.

Chao, W, Spragg, R G, Smith, R M

Surfactant has been shown to inhibit the production of reactive oxygen intermediates by various cells including alveolar macrophages and peripheral blood neutrophils. Superoxide O2-. production by...

Conservation of an intact human immunodeficiency virus type 1 vif gene in vitro and in vivo.

Sova, P, Van Ranst, M, Gupta, P, Balachandran, R, Chao, W, Itescu, S, ...

Replication of vif-negative human immunodeficiency virus type 1 (HIV-1) is attenuated in certain cell lines and highly impaired in peripheral blood lymphocytes in vitro. To determine whether intact...

Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes.

Simm, M, Shahabuddin, M, Chao, W, Allan, J S, Volsky, D J

Productive, spreading infection of peripheral blood lymphocytes (PBL) with human immunodeficiency virus type 1 (HIV-1) requires the viral protein Vif. To study the requirement for vif in this system,...

Interference to human immunodeficiency virus type 1 infection in the absence of downmodulation of the principal virus receptor, CD4.

Volsky, D J, Simm, M, Shahabuddin, M, Li, G, Chao, W, Potash, M J

It is thought that interference during human immunodeficiency virus type 1 (HIV-1) infection is established by downmodulation of the principal virus receptor, CD4. Here we present evidence to the...

vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus.

Chowdhury, I H, Chao, W, Potash, M J, Sova, P, Gendelman, H E, Volsky, D J

The vif gene of human immunodeficiency virus type 1 (HIV-1) is required for efficient infection of primary T lymphocytes. In this study, we investigated in detail the role of vif in productive...

Human immunodeficiency virus type 1 (HIV-1) protein Vif inhibits the activity of HIV-1 protease in bacteria and in vitro.

Kotler, M, Simm, M, Zhao, Y S, Sova, P, Chao, W, Ohnona, S F, ...

Human immunodeficiency virus type 1 (HIV-1) Vif is required for productive infection of T lymphocytes and macrophages. Virions produced in the absence of Vif have abnormal core morphology and those...

Cysteine residues in the Vif protein of human immunodeficiency virus type 1 are essential for viral infectivity.

Ma, X Y, Sova, P, Chao, W, Volsky, D J

The infectivity factor of human immunodeficiency virus type 1 (HIV-1), Vif, contains two cysteine residues which are highly conserved among animal lentiviruses. We introduced substitutions of leucine...

Infection of macrophages with lymphotropic human immunodeficiency virus type 1 can be arrested after viral DNA synthesis.

Huang, Z B, Potash, M J, Simm, M, Shahabuddin, M, Chao, W, Gendelman, H E, ...

Lymphotropic strains of human immunodeficiency virus type 1 (HIV-1), including HTLV-IIIB, replicate poorly in macrophages. We have shown previously that lymphotropic HIV-1 fuses equally well with T...

Protein tyrosine phosphorylation and regulation of the receptor for platelet-activating factor in rat Kupffer cells. Effect of sodium vanadate.

Chao, W, Liu, H, Hanahan, D J, Olson, M S

Platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine, AGEPC) and sodium vanadate (a phosphotyrosine phosphatase inhibitor) induced a time- and concentration-dependent increase...

Platelet-activating factor: receptors and signal transduction.

Chao, W, Olson, M S

During the past two decades, studies describing the chemistry and biology of PAF have been extensive. This potent phosphoacylglycerol exhibits a wide variety of physiological and pathophysiological...

Biosynthesis of platelet-activating factor by cultured rat Kupffer cells stimulated with calcium ionophore A23187.

Chao, W, Siafaka-Kapadai, A, Olson, M S, Hanahan, D J

Cultured rat Kupffer cells synthesize and release platelet-activating factor (PAF) when stimulated with calcium ionophore A23187. The production of PAF is concentration- and time-dependent and, based...

Metabolism of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-PAF (1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) by cultured rat Kupffer cells.

Chao, W, Siafaka-Kapadai, A, Hanahan, D J, Olson, M S

The metabolism of platelet-activating factor (PAF; identified as AGEPC: 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-PAF (lyso-GEPC: 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) was...

Inhibitory effect of porcine surfactant on the respiratory burst oxidase in human neutrophils. Attenuation of p47phox and p67phox membrane translocation as the mechanism.

Chao, W, Spragg, R G, Smith, R M

Surfactant has been shown to inhibit the production of reactive oxygen intermediates by various cells including alveolar macrophages and peripheral blood neutrophils. Superoxide O2-. production by...

Conservation of an intact human immunodeficiency virus type 1 vif gene in vitro and in vivo.

Sova, P, Van Ranst, M, Gupta, P, Balachandran, R, Chao, W, Itescu, S, ...

Replication of vif-negative human immunodeficiency virus type 1 (HIV-1) is attenuated in certain cell lines and highly impaired in peripheral blood lymphocytes in vitro. To determine whether intact...

Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes.

Simm, M, Shahabuddin, M, Chao, W, Allan, J S, Volsky, D J

Productive, spreading infection of peripheral blood lymphocytes (PBL) with human immunodeficiency virus type 1 (HIV-1) requires the viral protein Vif. To study the requirement for vif in this system,...

Interference to human immunodeficiency virus type 1 infection in the absence of downmodulation of the principal virus receptor, CD4.

Volsky, D J, Simm, M, Shahabuddin, M, Li, G, Chao, W, Potash, M J

It is thought that interference during human immunodeficiency virus type 1 (HIV-1) infection is established by downmodulation of the principal virus receptor, CD4. Here we present evidence to the...

vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus.

Chowdhury, I H, Chao, W, Potash, M J, Sova, P, Gendelman, H E, Volsky, D J

The vif gene of human immunodeficiency virus type 1 (HIV-1) is required for efficient infection of primary T lymphocytes. In this study, we investigated in detail the role of vif in productive...

Human immunodeficiency virus type 1 (HIV-1) protein Vif inhibits the activity of HIV-1 protease in bacteria and in vitro.

Kotler, M, Simm, M, Zhao, Y S, Sova, P, Chao, W, Ohnona, S F, ...

Human immunodeficiency virus type 1 (HIV-1) Vif is required for productive infection of T lymphocytes and macrophages. Virions produced in the absence of Vif have abnormal core morphology and those...

Cysteine residues in the Vif protein of human immunodeficiency virus type 1 are essential for viral infectivity.

Ma, X Y, Sova, P, Chao, W, Volsky, D J

The infectivity factor of human immunodeficiency virus type 1 (HIV-1), Vif, contains two cysteine residues which are highly conserved among animal lentiviruses. We introduced substitutions of leucine...

Infection of macrophages with lymphotropic human immunodeficiency virus type 1 can be arrested after viral DNA synthesis.

Huang, Z B, Potash, M J, Simm, M, Shahabuddin, M, Chao, W, Gendelman, H E, ...

Lymphotropic strains of human immunodeficiency virus type 1 (HIV-1), including HTLV-IIIB, replicate poorly in macrophages. We have shown previously that lymphotropic HIV-1 fuses equally well with T...

Protein tyrosine phosphorylation and regulation of the receptor for platelet-activating factor in rat Kupffer cells. Effect of sodium vanadate.

Chao, W, Liu, H, Hanahan, D J, Olson, M S

Platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine, AGEPC) and sodium vanadate (a phosphotyrosine phosphatase inhibitor) induced a time- and concentration-dependent increase...

Platelet-activating factor: receptors and signal transduction.

Chao, W, Olson, M S

During the past two decades, studies describing the chemistry and biology of PAF have been extensive. This potent phosphoacylglycerol exhibits a wide variety of physiological and pathophysiological...

Biosynthesis of platelet-activating factor by cultured rat Kupffer cells stimulated with calcium ionophore A23187.

Chao, W, Siafaka-Kapadai, A, Olson, M S, Hanahan, D J

Cultured rat Kupffer cells synthesize and release platelet-activating factor (PAF) when stimulated with calcium ionophore A23187. The production of PAF is concentration- and time-dependent and, based...

Metabolism of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-PAF (1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) by cultured rat Kupffer cells.

Chao, W, Siafaka-Kapadai, A, Hanahan, D J, Olson, M S

The metabolism of platelet-activating factor (PAF; identified as AGEPC: 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-PAF (lyso-GEPC: 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) was...

Evidence for platelet-activating factor as a late-phase mediator of chronic pancreatitis in the rat.

Zhou, W. G., Chao, W., Levine, B. A., Olson, M. S.

The role of platelet-activating factor (PAF) as a mediator of pancreatic inflammation was examined in the rat pancreatic duct ligation model of obstructive pancreatitis. Pancreatic generation of PAF,...