Mitchell,W. D., St. John,E. A.
The availability of active graphic hardware components in conjunction with modern high-speed computers permits the development of man-machine interactive graphic computer programs which can be used...
Complex nature of serum lysozyme activity: evidence of thermolability in inflammatory bowel disease.
Ward, M, Mitchell, W D, Eastwood, M
In patients with Crohn's disease and ulcerative colitis, alterations in serum storage temperature produced significant changes in serum lysozyme activity (SLA) as measured by the lysoplate method....
Marenah, C B, Lewis, B, Hassall, D, La Ville, A, Cortese, C, Mitchell, W D, ...
Some epidemiological studies have suggested an inverse relation between serum cholesterol concentration and mortality from cancer. Two hypotheses that might explain such a relation were investigated....
Cerebrotendinous xanthomatosis: biochemical response to inhibition of cholesterol synthesis.
Lewis, B, Mitchell, W D, Marenah, C B, Cortese, C, Reynolds, E H, Shakir, R
Effects of Dietary Supplements of Wheat Bran and Cellulose on Faeces and Bowel Function
Eastwood, M. A., Kirkpatrick, J. R., Mitchell, W. D., Bone, Ann, Hamilton, T.
In a study of bowel function in normal subjects wheat bran or cellulose was added to the diet for four weeks (16 g/day). Stool weight increased. Intestinal transit time did not significantly alter....
Action of Different Bran Preparations on Colonic Function
Kirwan, W. O., Smith, A. N., McConnell, A. A., Mitchell, W. D., Eastwood, M. A.
Two different types of commercially available bran were studied. One of these was composed of flake-like particles (coarse bran) whereas the other had smaller, finer particles with a floury component...
Complex nature of serum lysozyme activity: evidence of thermolability in inflammatory bowel disease.
Ward, M, Mitchell, W D, Eastwood, M
In patients with Crohn's disease and ulcerative colitis, alterations in serum storage temperature produced significant changes in serum lysozyme activity (SLA) as measured by the lysoplate method....
Marenah, C B, Lewis, B, Hassall, D, La Ville, A, Cortese, C, Mitchell, W D, ...
Some epidemiological studies have suggested an inverse relation between serum cholesterol concentration and mortality from cancer. Two hypotheses that might explain such a relation were investigated....
Cerebrotendinous xanthomatosis: biochemical response to inhibition of cholesterol synthesis.
Lewis, B, Mitchell, W D, Marenah, C B, Cortese, C, Reynolds, E H, Shakir, R
Effects of Dietary Supplements of Wheat Bran and Cellulose on Faeces and Bowel Function
Eastwood, M. A., Kirkpatrick, J. R., Mitchell, W. D., Bone, Ann, Hamilton, T.
In a study of bowel function in normal subjects wheat bran or cellulose was added to the diet for four weeks (16 g/day). Stool weight increased. Intestinal transit time did not significantly alter....
Action of Different Bran Preparations on Colonic Function
Kirwan, W. O., Smith, A. N., McConnell, A. A., Mitchell, W. D., Eastwood, M. A.
Two different types of commercially available bran were studied. One of these was composed of flake-like particles (coarse bran) whereas the other had smaller, finer particles with a floury component...
Variation in the incidence of diverticular disease within the city of Edinburgh.
Eastwood, M A, Sanderson, J, Pocock, S J, Mitchell, W D
An estimate of the incidence of diverticular disease of the colon was based on all the barium enema examinations in Edinburgh over four years (12 335 cases); using the census data for 1971, incidence...
The physical state of bile acids in the diarrhoeal stool of ileal dysfunction
Findlay, J. M., Eastwood, M. A., Mitchell, W. D.
A method is described for the separation of a diarrhoeal stool into solid and liquid phases. The seven patients studied had varying degrees of ileal resection. Faecal bile acids were measured in...
Bile acids in the diarrhoea of ileal resection
Mitchell, W. D., Findlay, J. M., Prescott, R. J., Eastwood, M. A., Horn, D. B.
Twenty individual diarrhoeal stools from three patients with ileal resection were centrifuged at 14 000 g for one hour at 10°C to separate the stool into pellet and supernatant. Bile acids and...
Intestinal streaming patterns in cholerrhoeic enteropathy and diverticular disease
Findlay, J. M., Mitchell, W. D., Eastwood, M. A., Anderson, A. J. B., Smith, A. N.
Streaming of gastrointestinal contents depends on the demonstration of differential rates of recovery of equal doses of two synchronously fed markers. There was no significant difference in the rate...
Bile acids and colonic motility in the rabbit and the human.
Kirwan, W O, Smith, A N, Mitchell, W D, Falconer, J D, Eastwood, M A
Colonic motor activity was initiated by infusions of bile salts into the caecum or rectum of the anaesthetized rabbit. Primary bile acids were examined proximally and distally in the colon and...
Effect of changing dietary sodium on the airway response to histamine.
Burney, P G, Neild, J E, Twort, C H, Chinn, S, Jones, T D, Mitchell, W D, ...
The airway response to histamine has been shown to be related to the 24 hour urinary excretion of sodium. To assess whether this relation is likely to represent a direct causal association a...