W. G. Kelly

Isolation and characterization of human fecal bacteria capable of 21-dehydroxylating corticoids.

Bokkenheuser, V D, Winter, J, Dehazya, P, Kelly, W G

It has been known for a decade that human intestinal flora include organisms capable of 21-dehydroxylating corticoids. Yet the identity of the organisms synthesizing 21-dehydroxylase has remained...

ATP inhibits nuclear and mitochondrial type I topoisomerases from human leukemia cells.

Castora, F J, Kelly, W G

Type I topoisomerases have been purified from nuclei and mitochondria of human acute lymphoblastic leukemia cells. Both of these ATP-independent enzymes are actually found to be inhibited by ATP at...

Distinct Requirements for Somatic and Germline Expression of a Generally Expressed Caernorhabditis Elegans Gene

Kelly, W. G., Xu, S., Montgomery, M. K., Fire, A.

In screening for embryonic-lethal mutations in Caenorhabditis elegans, we defined an essential gene (let-858) that encodes a nuclear protein rich in acidic and basic residues. We have named this...

Isolation and characterization of human fecal bacteria capable of 21-dehydroxylating corticoids.

Bokkenheuser, V D, Winter, J, Dehazya, P, Kelly, W G

It has been known for a decade that human intestinal flora include organisms capable of 21-dehydroxylating corticoids. Yet the identity of the organisms synthesizing 21-dehydroxylase has remained...

ATP inhibits nuclear and mitochondrial type I topoisomerases from human leukemia cells.

Castora, F J, Kelly, W G

Type I topoisomerases have been purified from nuclei and mitochondria of human acute lymphoblastic leukemia cells. Both of these ATP-independent enzymes are actually found to be inhibited by ATP at...

Distinct Requirements for Somatic and Germline Expression of a Generally Expressed Caernorhabditis Elegans Gene

Kelly, W. G., Xu, S., Montgomery, M. K., Fire, A.

In screening for embryonic-lethal mutations in Caenorhabditis elegans, we defined an essential gene (let-858) that encodes a nuclear protein rich in acidic and basic residues. We have named this...