An Ars Silencer Binding-Factor Also Activates 2 Ribosomal-Protein Genes in Yeast (1989)
Dorsman, J.C., Doorenbosch, M.M., Maurer, C.T.C., Winde, J.H. De, Mager, W.H., Planta, R.J., ...
A new nomenclature for the cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.
Mager, W H, Planta, R J, Ballesta, J G, Lee, J C, Mizuta, K, Suzuki, K, ...
The availability of the complete sequence of the Saccharomyces cerevisiae genome has allowed a comprehensive analysis of the genes encoding cytoplasmic ribosomal proteins in this organism. On the...
Varela, J C, Praekelt, U M, Meacock, P A, Planta, R J, Mager, W H
The HSP12 gene encodes one of the two major small heat shock proteins of Saccharomyces cerevisiae. Hsp12 accumulates massively in yeast cells exposed to heat shock, osmostress, oxidative stress, and...
Stress-induced transcriptional activation.
Living cells, both prokaryotic and eukaryotic, employ specific sensory and signalling systems to obtain and transmit information from their environment in order to adjust cellular metabolism, growth,...
Analysis of upstream activation sites of yeast ribosomal protein genes.
Woudt, L P, Mager, W H, Nieuwint, R T, Wassenaar, G M, Van Der Kuyl, A C, Murre, J J, ...
Transcription of the gene encoding yeast ribosomal protein L25 was previously shown to be activated through tandemly arranged upstream sequence elements that most rp-genes in yeast have in common. A...
Gonçalves, P M, Griffioen, G, Minnee, R, Bosma, M, Kraakman, L S, Mager, W H, ...
All ribosomal protein (rp) gene promoters from Saccharomyces cerevisiae studied so far contain either (usually two) binding sites for the global gene regulator Rap1p or one binding site for another...
An ARS/silencer binding factor also activates two ribosomal protein genes in yeast.
Dorsman, J C, Doorenbosch, M M, Maurer, C T, De Winde, J H, Mager, W H, Planta, R J, ...
GFI is an abundant yeast DNA-binding protein, capable of binding to both ARS sequences and to the upstream regions of a number of nuclear genes coding for mitochondrial proteins (Dorsman et al.,...
Structural comparison of yeast ribosomal protein genes.
Leer, R J, Van Raamsdonk-Duin, M M, Hagendoorn, M J, Mager, W H, Planta, R J
The primary structure of the genes encoding the yeast ribosomal proteins L17a and L25 was determined, as well as the positions of the 5'- and 3'-termini of the corresponding mRNAs. Comparison of the...
Structure and organization of two linked ribosomal protein genes in yeast.
Molenaar, C M, Woudt, L P, Jansen, A E, Mager, W H, Planta, R J, Donovan, D M, ...
The genes encoding yeast ribosomal proteins rp28 and S16A are linked and occur duplicated in the yeast genome. In both gene pairs the genes are approximately 600 bp apart and are both transcribed in...
A comparison of yeast ribosomal protein gene DNA sequences.
Teem, J L, Abovich, N, Kaufer, N F, Schwindinger, W F, Warner, J R, Levy, A, ...
The DNA sequences of eight yeast ribosomal protein genes have been compared for the purpose of identifying homologous regions which may be involved in the coordinate regulation of ribosomal protein...
The structure of the gene coding for the phosphorylated ribosomal protein S10 in yeast.
Leer, R J, Van Raamsdonk-Duin, M M, Molenaar, C M, Cohen, L H, Mager, W H, Planta, R J
From previous studies on cloned yeast ribosomal protein genes we obtained evidence that a large number of them contain an intron [Bollen et al. (1982) Gene 18, 29-38]. In the temperature-sensitive...
Yeast contains two functional genes coding for ribosomal protein S10.
Leer, R J, Van Raamsdonk-Duin, M M, Molenaar, C M, Witsenboer, H M, Mager, W H, Planta, R J
The DNA sequence of the second copy of the gene coding for yeast ribosomal protein S10 was determined and compared with the sequence of the first gene-copy. In addition, the sites at which the...
Correct removal by splicing of a Neurospora intron in yeast.
Woudt, L P, Van Den Heuvel, J J, Van Raamsdonk-Duin, M M, Mager, W H, Planta, R J
Processing of intron-containing nuclear messenger RNAs in yeast require an internal conserved sequence (ICS) element, UACUAAC. Similar elements (ugCUAGAC) have been identified in sequences...
Woudt, L P, Pastink, A, Kempers-Veenstra, A E, Jansen, A E, Mager, W H, Planta, R J
Sequences coding for histone H3 and H4 of Neurospora crassa could be identified in genomic digests with the use of the corresponding genes from sea urchin and X. laevis as hybridization probes. A 2.6...
Yeast ribosomal protein S33 is encoded by an unsplit gene.
Leer, R J, Van Raamsdonk-Duin, M M, Schoppink, P J, Cornelissen, M T, Cohen, L H, Mager, W H, ...
The structure of the gene coding for ribosomal protein S33, - a protein which escapes the coordinate control of ribosomal protein synthesis in rna 2 mutant cells -, was determined by sequence...
Herruer, M H, Mager, W H, Doorenbosch, T M, Wessels, P L, Wassenaar, T M, Planta, R J
At least 4 different, protein binding cis-acting elements are present in the upstream region of the S33-gene. The major protein binding site is situated between positions -148 and -163 relative to...
Kraakman, L S, Mager, W H, Maurer, K T, Nieuwint, R T, Planta, R J
Transcription of the majority of the ribosomal protein (rp) genes in yeast is activated through common cis-acting elements, designated RPG-boxes. These elements have been shown to act as specific...
Human pancreatic amylase is encoded by two different genes.
Groot, P C, Bleeker, M J, Pronk, J C, Arwert, F, Mager, W H, Planta, R J, ...
Herruer, M H, Mager, W H, Raué, H A, Vreken, P, Wilms, E, Planta, R J
Shifting the temperature of a yeast culture from 23 degrees to 36 degrees C results in a sudden and severe (greater than 85%) decline in the cellular levels of ribosomal protein (rp-)mRNAs. Recovery...
Transcriptional control of yeast ribosomal protein synthesis during carbon-source upshift.
Herruer, M H, Mager, W H, Woudt, L P, Nieuwint, R T, Wassenaar, G M, Groeneveld, P, ...
Shifting a yeast culture from an ethanol-based medium to a glucose-based medium causes a coordinate increase of the cellular levels of ribosomal protein mRNAs by about a factor 4 within 30 min....
The genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed.
Leer, R J, Van Raamsdonk-Duin, M M, Kraakman, P, Mager, W H, Planta, R J
Unlike most yeast ribosomal protein genes studied so far the genes coding for S24 and L46 are adjacent on the genome. Sequence analysis showed that the two genes are transcribed divergently, their...
Twisk, J, Hoekman, M F, Mager, W H, Moorman, A F, De Boer, P A, Scheja, L, ...
We investigated the lobular localization and molecular level of expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase, two key enzymes in bile acid synthesis, in isolated periportal...
Specific binding of TUF factor to upstream activation sites of yeast ribosomal protein genes.
Vignais, M L, Woudt, L P, Wassenaar, G M, Mager, W H, Sentenac, A, Planta, R J
Transcription activation of yeast ribosomal protein genes is mediated through homologous, 12-nucleotide-long and, in general, duplicated upstream promoter elements (HOMOL1 and RPG, referred to as...
Woudt, L P, Smit, A B, Mager, W H, Planta, R J
Previous studies have revealed the occurrence of two closely linked conserved sequence elements, designated as HOMOL 1 and RPG box, in front of most yeast ribosomal protein genes examined. To...
Modification of yeast ribosomal proteins. Methylation.
Kruiswijk, T, Kunst, A, Planta, R J, Mager, W H
Two-dimensional polyacrylamide-gel electrophoretic analysis of yeast ribosomal proteins uniformly labelled in vivo with [methyl-3H]methionine and [1-14C]methionine revealed that four ribosomal...
Analysis of histones from the yeast Saccharomyces carlsbergensis.
Pastink, A, Berkhout, T A, Mager, W H, Planta, R J
Basic chromosomal proteins were isolated from the chromatin of the yeast Saccharomyces carlsbergensis by extraction with H2SO4 and were purified by ion-exchange chromatography. Electrophoresis of the...
Post, S M, Twisk, J, Van Der Fits, L, De Wit, E C, Hoekman, M F, Mager, W H, ...
Lipoproteins may supply substrate for the formation of bile acids, and the amount of hepatic cholesterol can regulate bile-acid synthesis and increase cholesterol 7alpha-hydroxylase expression....
Darley, C P, Van Wuytswinkel , O C, Van Der Woude , K, Mager, W H, De Boer , A H
Sodium at high millimolar levels in the cytoplasm is toxic to plant and yeast cells. Sequestration of Na(+) ions into the vacuole is one mechanism to confer Na(+)-tolerance on these organisms. In the...
Kluyveromyces contains a functional ABF1-homologue.
Gonçalves, P M, Maurer, K, Mager, W H, Planta, R J
ABF1 is a multifunctional protein present in Saccharomyces cerevisiae, involved in transcription-activation and -repression as well as in DNA-replication. Several lines of evidence indicate the...
A new nomenclature for the cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.
Mager, W H, Planta, R J, Ballesta, J G, Lee, J C, Mizuta, K, Suzuki, K, ...
The availability of the complete sequence of the Saccharomyces cerevisiae genome has allowed a comprehensive analysis of the genes encoding cytoplasmic ribosomal proteins in this organism. On the...
Varela, J C, Praekelt, U M, Meacock, P A, Planta, R J, Mager, W H
The HSP12 gene encodes one of the two major small heat shock proteins of Saccharomyces cerevisiae. Hsp12 accumulates massively in yeast cells exposed to heat shock, osmostress, oxidative stress, and...
Stress-induced transcriptional activation.
Living cells, both prokaryotic and eukaryotic, employ specific sensory and signalling systems to obtain and transmit information from their environment in order to adjust cellular metabolism, growth,...
Analysis of upstream activation sites of yeast ribosomal protein genes.
Woudt, L P, Mager, W H, Nieuwint, R T, Wassenaar, G M, Van Der Kuyl, A C, Murre, J J, ...
Transcription of the gene encoding yeast ribosomal protein L25 was previously shown to be activated through tandemly arranged upstream sequence elements that most rp-genes in yeast have in common. A...
Gonçalves, P M, Griffioen, G, Minnee, R, Bosma, M, Kraakman, L S, Mager, W H, ...
All ribosomal protein (rp) gene promoters from Saccharomyces cerevisiae studied so far contain either (usually two) binding sites for the global gene regulator Rap1p or one binding site for another...
Kluyveromyces contains a functional ABF1-homologue.
Gonçalves, P M, Maurer, K, Mager, W H, Planta, R J
ABF1 is a multifunctional protein present in Saccharomyces cerevisiae, involved in transcription-activation and -repression as well as in DNA-replication. Several lines of evidence indicate the...
An ARS/silencer binding factor also activates two ribosomal protein genes in yeast.
Dorsman, J C, Doorenbosch, M M, Maurer, C T, De Winde, J H, Mager, W H, Planta, R J, ...
GFI is an abundant yeast DNA-binding protein, capable of binding to both ARS sequences and to the upstream regions of a number of nuclear genes coding for mitochondrial proteins (Dorsman et al.,...
Structural comparison of yeast ribosomal protein genes.
Leer, R J, Van Raamsdonk-Duin, M M, Hagendoorn, M J, Mager, W H, Planta, R J
The primary structure of the genes encoding the yeast ribosomal proteins L17a and L25 was determined, as well as the positions of the 5'- and 3'-termini of the corresponding mRNAs. Comparison of the...
Structure and organization of two linked ribosomal protein genes in yeast.
Molenaar, C M, Woudt, L P, Jansen, A E, Mager, W H, Planta, R J, Donovan, D M, ...
The genes encoding yeast ribosomal proteins rp28 and S16A are linked and occur duplicated in the yeast genome. In both gene pairs the genes are approximately 600 bp apart and are both transcribed in...
A comparison of yeast ribosomal protein gene DNA sequences.
Teem, J L, Abovich, N, Kaufer, N F, Schwindinger, W F, Warner, J R, Levy, A, ...
The DNA sequences of eight yeast ribosomal protein genes have been compared for the purpose of identifying homologous regions which may be involved in the coordinate regulation of ribosomal protein...
The structure of the gene coding for the phosphorylated ribosomal protein S10 in yeast.
Leer, R J, Van Raamsdonk-Duin, M M, Molenaar, C M, Cohen, L H, Mager, W H, Planta, R J
From previous studies on cloned yeast ribosomal protein genes we obtained evidence that a large number of them contain an intron [Bollen et al. (1982) Gene 18, 29-38]. In the temperature-sensitive...
Yeast contains two functional genes coding for ribosomal protein S10.
Leer, R J, Van Raamsdonk-Duin, M M, Molenaar, C M, Witsenboer, H M, Mager, W H, Planta, R J
The DNA sequence of the second copy of the gene coding for yeast ribosomal protein S10 was determined and compared with the sequence of the first gene-copy. In addition, the sites at which the...
Correct removal by splicing of a Neurospora intron in yeast.
Woudt, L P, Van Den Heuvel, J J, Van Raamsdonk-Duin, M M, Mager, W H, Planta, R J
Processing of intron-containing nuclear messenger RNAs in yeast require an internal conserved sequence (ICS) element, UACUAAC. Similar elements (ugCUAGAC) have been identified in sequences...
Woudt, L P, Pastink, A, Kempers-Veenstra, A E, Jansen, A E, Mager, W H, Planta, R J
Sequences coding for histone H3 and H4 of Neurospora crassa could be identified in genomic digests with the use of the corresponding genes from sea urchin and X. laevis as hybridization probes. A 2.6...
Yeast ribosomal protein S33 is encoded by an unsplit gene.
Leer, R J, Van Raamsdonk-Duin, M M, Schoppink, P J, Cornelissen, M T, Cohen, L H, Mager, W H, ...
The structure of the gene coding for ribosomal protein S33, - a protein which escapes the coordinate control of ribosomal protein synthesis in rna 2 mutant cells -, was determined by sequence...
Herruer, M H, Mager, W H, Doorenbosch, T M, Wessels, P L, Wassenaar, T M, Planta, R J
At least 4 different, protein binding cis-acting elements are present in the upstream region of the S33-gene. The major protein binding site is situated between positions -148 and -163 relative to...
Kraakman, L S, Mager, W H, Maurer, K T, Nieuwint, R T, Planta, R J
Transcription of the majority of the ribosomal protein (rp) genes in yeast is activated through common cis-acting elements, designated RPG-boxes. These elements have been shown to act as specific...
Human pancreatic amylase is encoded by two different genes.
Groot, P C, Bleeker, M J, Pronk, J C, Arwert, F, Mager, W H, Planta, R J, ...
Herruer, M H, Mager, W H, Raué, H A, Vreken, P, Wilms, E, Planta, R J
Shifting the temperature of a yeast culture from 23 degrees to 36 degrees C results in a sudden and severe (greater than 85%) decline in the cellular levels of ribosomal protein (rp-)mRNAs. Recovery...
Transcriptional control of yeast ribosomal protein synthesis during carbon-source upshift.
Herruer, M H, Mager, W H, Woudt, L P, Nieuwint, R T, Wassenaar, G M, Groeneveld, P, ...
Shifting a yeast culture from an ethanol-based medium to a glucose-based medium causes a coordinate increase of the cellular levels of ribosomal protein mRNAs by about a factor 4 within 30 min....
The genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed.
Leer, R J, Van Raamsdonk-Duin, M M, Kraakman, P, Mager, W H, Planta, R J
Unlike most yeast ribosomal protein genes studied so far the genes coding for S24 and L46 are adjacent on the genome. Sequence analysis showed that the two genes are transcribed divergently, their...
Twisk, J, Hoekman, M F, Mager, W H, Moorman, A F, De Boer, P A, Scheja, L, ...
We investigated the lobular localization and molecular level of expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase, two key enzymes in bile acid synthesis, in isolated periportal...
Specific binding of TUF factor to upstream activation sites of yeast ribosomal protein genes.
Vignais, M L, Woudt, L P, Wassenaar, G M, Mager, W H, Sentenac, A, Planta, R J
Transcription activation of yeast ribosomal protein genes is mediated through homologous, 12-nucleotide-long and, in general, duplicated upstream promoter elements (HOMOL1 and RPG, referred to as...
Woudt, L P, Smit, A B, Mager, W H, Planta, R J
Previous studies have revealed the occurrence of two closely linked conserved sequence elements, designated as HOMOL 1 and RPG box, in front of most yeast ribosomal protein genes examined. To...
Modification of yeast ribosomal proteins. Methylation.
Kruiswijk, T, Kunst, A, Planta, R J, Mager, W H
Two-dimensional polyacrylamide-gel electrophoretic analysis of yeast ribosomal proteins uniformly labelled in vivo with [methyl-3H]methionine and [1-14C]methionine revealed that four ribosomal...
Analysis of histones from the yeast Saccharomyces carlsbergensis.
Pastink, A, Berkhout, T A, Mager, W H, Planta, R J
Basic chromosomal proteins were isolated from the chromatin of the yeast Saccharomyces carlsbergensis by extraction with H2SO4 and were purified by ion-exchange chromatography. Electrophoresis of the...
Post, S M, Twisk, J, Van Der Fits, L, De Wit, E C, Hoekman, M F, Mager, W H, ...
Lipoproteins may supply substrate for the formation of bile acids, and the amount of hepatic cholesterol can regulate bile-acid synthesis and increase cholesterol 7alpha-hydroxylase expression....
Darley, C P, Van Wuytswinkel , O C, Van Der Woude , K, Mager, W H, De Boer , A H
Sodium at high millimolar levels in the cytoplasm is toxic to plant and yeast cells. Sequestration of Na(+) ions into the vacuole is one mechanism to confer Na(+)-tolerance on these organisms. In the...