Increased arginine vasopressin mRNA expression in the human hypothalamus in depression: A preliminary report (2006)
Meynen, G.,
Unmehopa, U.A.,
Heerikhuize, J.J. Van,
Hofman, M.A.,
Swaab, D.F.,
Hoogendijk, W.J.G.
Background: Elevated arginine vasopressin (AVP) plasma levels have been observed in major depression, particularly in relation to the melancholic subtype. Two hypothalamic structures produce plasma...
Prediction of treatment response by HPA-axis and glucocorticoid receptor polymorphisms in major depression (2006)
Brouwer, J.P.,
Appelhof, B.C.,
Koper, J.W.,
Fliers, E.,
Huyser, J,
...
Objective: We investigated whether treatment response is predicted by hypothalamus-pituitary-adrenal (HPA) axis parameters, or by genetic polymorphisms in the glucocorticoid receptor (GR), that...
Glucocorticoids and relapse of major depression (dexamethasone/corticotropin-releasing hormone test in relation to relapse of major depression) (2006)
Appelhof, B.C.,
Huyser, J,
Verweij, M.,
Brouwer, J.P.,
Dyck, R. Van,
Fliers, E.,
...
Background: Knowledge of pathogenic mechanisms and predictors of relapse in major depressive disorder is still limited. Hypothalamic-pituitary-adrenocortical (HPA) axis dysregulation is thought to be...
Thyrotropin, but not a polymorphism in type II deiodinase, predicts response to paroxetine in major depression (2006)
Brouwer, J.P.,
Appelhof, B.C.,
Peeters, R.P.,
Hoogendijk, W.J.G.,
Huyser, J,
Schene, A.H.,
...
Polymorphisms in type 2 deiodinase are not associated with well-being, neurocognitive functioning, and preference for combined thyroxine/3,5,3 '-triiodothyronine therapy (2005)
Appelhof, B.C.,
Peeters, R.P.,
Wiersinga, W.M.,
Visser, Th.J.,
Wekking, E.M.,
Huyser, J,
...
Thyroid and adrenal axis in major depression: a controlled study in outpatients (2005)
Brouwer, J.P.,
Appelhof, B.C.,
Hoogendijk, W.J.G.,
Huyser, J,
Endert, E.,
Zuketto, C.,
...
Triiodothyronine addition to paroxetine in the treatment of major depressive disorder (2004)
Appelhof, B.C.,
Brouwer, J.P.,
Dyck, R. Van,
Fliers, E.,
Hoogendijk, W.J.G.,
Huyser, J,
...
Decreased thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus (PVN) of patients with major depression (2003)
Alkemade, A.,
Unmehopa, U.A.,
Brouwer, J.P.,
Hoogendijk, W.J.G.,
Wiersinga, W.M.,
Swaab, D.F.,
...
Decreased thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus of patients with major depression [letter] (2003)
Alkemade, A.,
Ummehopa, U.A.,
Brouwer, J.P.,
Hoogendijk, W.J.G.,
Wiersinga, W.M.,
Swaab, D.F.,
...
Decreased thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus of patients with major depression [research letter] (2003)
Alkemade, J.M.,
Ummehopa, U.A.,
Brouwer, J.P.,
Hoogendijk, W.J.G.,
Wiersinga, W.M.,
Swaab, D.F.,
...
Amisulpride: Is there a treatment for negative symptoms in schizophrenia patients? (2002)
Storosum, J.G.,
Elferink, A.J.A.,
Zwieten, B.J. Van,
Strik, R. Van,
Hoogendijk, W.J.G.,
Broekmans, A.W.
Amisulpride: Is there a treatment for negative symptoms in schizophrenia patients? (2002)
Storosum, J.G.,
Elferink, A.J.A.,
Zwieten, B.J. Van,
Strik, R. Van,
Hoogendijk, W.J.G.,
Broekmans, A.W.
Verhoogde activiteit van stressregulerende systemen bij de ziekte van Alzheime (2001)
Hoogendijk, W.J.G.,
Meynen, G.,
GFeenstra, M.G.,
Eikelenboom, P.,
Kamphorst, W.,
Swaab, D.F.
Hippocampal apoptosis in major depression is a rare event and absent from subareas at risk for glucocorticoid overexposure (2001)
Lucassen, P.J.,
Müller, M.B.,
Holsboer, F.,
Bauer, J.,
Holtrop, A.,
Wouda, J.,
...
Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus (2001)
Müller, M.B.,
Lucassen, P.J.,
Yassouridis, A.,
Hoogendijk, W.J.G.,
Holsboer, F,
Swaab, D.F.
Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression (2001)
Zhou, J.N.,
Riemersma, R.F.,
Unmehopa, U.A.,
Hoogendijk, W.J.G.,
Heerikhuize, J.J. Van,
Hofman, M.A.,
...
Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus (2001)
Muller, M.B.,
Lucassen, P.J.,
Yassouridis, A.,
Hoogendijk, W.J.G.,
Holsboer, F.,
Swaab, D.F.
Hippocampal apoptosis in major depression in a minor event and absent from subareas at risk for glucocorticoid overexposure (2001)
Lucassen, P.J.,
Muller, M.B.,
Holsboer, F.,
Bauer, J.,
Holtrop, A.,
Wouda, J.,
...
Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression (2001)
Zhou, J.N.,
Riemersma, R.F.,
Unmehopa, U.A.,
Hoogendijk, W.J.G.,
Heerikhuize, J.J. Van,
Hofman, M.A.,
...
Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus (2001)
Muller, M.B.,
Lucassen, P.J.,
Yassouridis, A.,
Hoogendijk, W.J.G.,
Holsboer, F.,
Swaab, D.F.
Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure (2001)
Lucassen, P.J.,
Muller, M.B.,
Holsboer, F.,
Bauer, J.,
Holtrop, A.,
Wouda, J.,
...
Verhoogde activiteit van stressregulerende systemen bij de ziekte van Alzheimer (2001)
Hoogendijk, W.J.G.,
Meynen, G.,
Feenstra, M.G.P.,
Eikelenboom, P.,
Kamphorst, W.,
Swaab, D.F.
Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus. (2001)
Müller, M. B.,
Lucassen, P. J.,
Yassouridis, A.,
Hoogendijk, W. J. G.,
Holsboer, F.,
Swaab, D. F.
Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure. (2001)
Lucassen, P. J.,
Müller, M. B.,
Holsboer, F.,
Bauer, J.,
Holtrop, A.,
Wouda, J.,
...
Decreased vasopressin gene expression in the biological clock of Alzheimer's disease patients with and without depression (2000)
Liu, R.Y.,
Zhou, J.N.,
Hoogendijk, W.J.G.,
Heerikhuize, J. Van,
Kamphorst, W.,
Unmehopa, U.A.,
...
Decreased vasopressin gene expression in the biological clock of Alzheimer disease patients with and without depression (2000)
Liu, R-Y.,
Zhou, J.N.,
Hoogendijk, W.J.G.,
Heerikhuize, J.J. Van,
Kamphorst, W.,
Unmehopa, U.A.,
...
Lack of association between depression and the loss of neurons in the locus coeruleus in Alzheimer's disease (1999)
Hoogendijk, W.J.G.,
Sommer, I.E.C.,
Pool, Ch.W.,
Kamphorst, W.,
Hofman, M.A.,
Eikelenboom, P.,
...
Increased activity of surviving locus coeruleus neurons in Alzheimer's disease (1999)
Hoogendijk, W.J.G.,
Feenstra, M.P.G.,
Botterblom, M.H.A.,
Gilhuis, J.,
Sommer, I.E.C.,
Kamphorst, W.,
...
Increased activity of surviving locus ceruleus neurons in Alzheimer's disease (1999)
Hoogendijk, W.J.G.,
Feenstra, M.G.P.,
Botterblom, M.H.A.,
Gilhuis, J.,
Sommer, I.E.C.,
Kamphorst, W.,
...
Lack of association between depression and loss of neurons in the locus coeruleus in Alzheimer disease (1999)
Hoogendijk, W.J.G.,
Sommer, I.E.C.,
Pool, C.W.,
Kamphorst, W.,
Hofman, M.A.,
Eikelenboom, P.,
...
Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer's diseases (1997)
Hoogendijk, W.J.G.,
Mirmiran, M.,
Hofman, M.A.,
Lucassen, P.J.,
Zhou, J.N.,
...
Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer's disease (1996)
Hoogendijk, W.J.G.,
Mirmiran, M.,
Hofman, M.A.,
Lucassen, P.J.,
Zhou, J.N.,
...
Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer's diseases (1996)
Hoogendijk, W.J.G.,
Mirmiran, M.,
Hofman, M.A.,
Lucassen, P.J.,
Zhou, J.N.,
...
Image-analyzer-assisted morphometry of the locus coeruleus in Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (1995)
Hoogendijk, W.J.G.,
Pool, C.W.,
Troost, D.,
Zwieten, E.J. Van,
Swaab, D.F.
Increased corticotropin-releasing hormone (CRH) mRNA in the paraventricular nucleus of patients with Alzheimer's disease or depression (1995)
Raadsheer, F.C.,
Heerikhuize, J.J. Van,
Lucassen, P.J.,
Hoogendijk, W.J.G.,
Tilders, F.J.H.,
Swaab, D.F.