W. J. G. Melchers

Homomultimerization of the coxsackievirus 2B protein in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy. (2002)

Kuppeveld, F.J.M. Van, Melchers, W.J.G., Gadella, Th.W.J., Willems, P.H.G.M.

The 2B protein of enteroviruses is the viral membrane-active protein that is responsible for the modifications in host cell membrane permeability that take place in enterovirus-infected cells. The 2B...

Enterovirus-induced production of pro-inflammatory and T-helper cytokines by human leukocytes (2000)

Galama, J.M.D., Melchers, W.J.G., Meer, J.W.M. Van Der, Netea, M.G., Wijnands, P.G.J.T.B., Vreugdenhil, G.R.

Outbreak of Amoxicillin-Resistant Haemophilus influenzae Type B: Variable Number of Tandem Repeats as Novel Molecular Markers (1997)

Meis, J.F.G.M., Verbrugh, H.A., Nohlmans, L., IJsseldijk, C., Melchers, W.J.G., Belkum, A. Van

Prenatal diagnosis and treatment of congenital toxoplasma gondii infections: an experimental study in rhesus monkeys [see comments] (1997)

Eskes, Tom K.A.B., Meuwissen, Joep H.E.Th., Galama, J.M.D., Melchers, W.J.G., Schoondermark-van De Ven, E.M.E.

Pseudo-outbreak of multi-resistant Pseudomonas aerigunosa in a haematology unit (1997)

Voss, A., Hoogkamp-Korstanje, J.A.A., Meis, J.F.G.M., Pauw, B.E., De, Melchers, W.J.G., Bijl, D., ...

Sepsis puerperalis caused by a genotypically proven cat-derived Pasteurella multocida strain (1997)

Steegers, E.A.P., Melchers, W.J.G., Meis, J.F.G.M., Zwam, Y.H.C.M., Van, Voss, A.

Analysis of an outbreak of puerperal fever due to group A streptococci by random amplified polymorphic DNA fingerprinting (1997)

Melchers, W.J.G., Voss, A., Berg, P.P., Van Den, Muytjens, H.L., Meis, J.F.G.M.

Structure-function analysis of coxsackie B3 virus protein 2B (1997)

Doedens, J.R., Kirkegaard, K., Melchers, W.J.G., Kuppeveld, F.J.M. Van

Two-Step Polymerase Chain Reaction Assay for Detection of Yersinia Species in General and of Pathogenic Yersinia enterocolitica Specifically (1997)

Melchers, W.J.G., Hoogkamp-Korstanje, J.A.A., Curfs, J.H.A.J., Meis, J.F.G.M., Odinot, P.T.

Association of infections with human immunodeficiency virus and human papillomavirus in Honduras (1997)

Figueroa, M., Velema, J.P., Melchers, W.J.G., Ferrera, A.

Chimeric coxsackie B3 virus genomes that express hybrid coxsackievirus-poliovirus 2B proteins: functional dissection of structural domains involved in RNA replication (1997)

Melchers, W.J.G., Galama, J.M.D., Vliet, W. Van Der, Hurk, P.J.J.C. Van Den, Kuppeveld, F.J.M. Van

Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release (1997)

Melchers, W.J.G., Galama, J.M.D., Dijkman, H.B.P.M., Willems, P.H.G.M., Smeets, R.L.L., Hoenderop, J.G.J., ...

A sero-epidemiological study of the relationship between sexually transmitted agents and cervical cancer in Honduras (1997)

Melchers, W.J.G., Velema, J.P., Figueroa, M., Herbrink, P., Baay, M.F.D., Ferrera, A.

Genetische Karakterisering van Enterobacter sakazakii isolaten van patiënten met neonatale meningitis (1997)

Melchers, W.J.G., Meis, J.F.G.M., Muytjens, H.L., Voss, A., Smeets, L.C.

Kissing of the two predominant hairpin loops in the coxsackie B virus 3' untranslated region is the essential structural feature of the origin of replication required for negative-strand RNA synthesis (1997)

Galama, J.M.D., Agol, V.I., Pilipenko, E.V., Pleij, C.W.A., Bruins Slot, H.J., Hoenderop, J.G.J., ...

Molecular mimicry in IDDM: The PEVKEK motif of coxsackie B virus protein 2C and glutamate decarboxylase binds to HLA-DR3 (1997)

Galama, J.M.D., Roep, B.O., Melchers, W.J.G., Ottenhoff, T.H.M., Geluk, A., Vreugdenhil, G.R.

Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release (1997)

Melchers, W.J.G., Galama, J.M.D., Dijkman, H.B.P.M., Willems, P.H.G.M., Smeets, R.L.L., Hoenderop, J.G.J., ...

Kissing of the two predominant hairpin loops in the coxsackie B virus 3' untranslated region is the essential structural feature of the origin of replication required for negative-strand RNA synthesis (1997)

Galama, J.M.D., Agol, V., Pilipenko, E., Pleij, C.W.A., Bruins Slot, H.J., Hoenderop, J.G.J., ...

Anti-toxoplasma effect of pyrimethamine, trimethoprim and sulphonamides alone and in combination: implications for therapy (1996)

Galama, J.M.D., Meer, J.W.M. Van Der, Koopmans, P.P., Melchers, W.J.G., Camps, W., Schoondermark-van De Ven, E.M.E., ...

Mengovirus leader is involved in the inhibition of host cell protein synthesis (1996)

Melchers, W.J.G., Kuppeveld, F.J.M. Van, Galama, J.M.D., Zoll, G.J.

Mutagenesis of the Coxsackie B3 virus 2B/2C cleavage site: determinants of processing efficiency and effects on viral replication (1996)

Melchers, W.J.G., Galama, J.M.D., Zoll, J., Hurk, P.J.J.C. Van Den, Kuppeveld, F.J.M. Van

Prenatale diagnostiek en behandeling van congenitale toxoplasma gondii-infecties (1996)

Eskes, T.K.A.B., Meuwissen, J.H.E.T., Melchers, W.J.G., Galama, J.M.D., Schoondermark-van De Ven, E.M.E.

Prolonged enteroviral infection in a patient who developed pericarditis and heart failure after bone marrow transplantation (1996)

Melchers, W.J.G., Peters, H., Wittebol, S., Leeuw, N., De, Galama, J.M.D.

Anti-Toxoplasma effect of Pyrimethamine, Trimethoprim and Sulphonamides alone and in combination: Implications for therapy (1996)

Galama, J.M.D., Meer, J.W.M. Van Der, Koopmans, P.P., Melchers, W.J.G., Camps, W., Schoondermark-van De Ven, E.M.E., ...

Staphylococcus epidermidis catheter-related infections in a short-bowel patient. Persistence of a singel strain over a two-year-period (1996)

Meis, J.F.G.M., Hoogkamp-Korstanje, J.A.A., Bijl, D., Melchers, W.J.G., Voss, A.

Use of interrepeat PCR fingerprinting to investigate an acinetobacter baumannii outbreak in an intensive care unit (1996)

Voss, A., Hoogkamp-Korstanje, J.A.A., Melchers, W.J.G., Meis, J.F.G.M., Debast, S.B.

Chronisch vermoeidheidssyndroom: spelen virusinfecties een rol? (1996)

Meer, J.W.M., Van Der, Melchers, W.J.G., Bleijenberg, G., Fennis, J.F.M., Vercoulen, J.H.M.M., Swanink, C.M.A., ...

Cis-element, oriR, involved in the initiation of (-)strand poliovirus RNA: a quasi-globular multi-domain RNA structure maintained by tertiary ("kissing") interactions (1996)

Agol, V.I., Bruins Slot, H.J., Melchers, W.J.G., Maslova, S.V., Poperechny, K.V., Pilipenko, E.V.

Coxsackie B3 virus protein 2B contains a cationic amphipathic helix that is required for viral RNA replication (1996)

Melchers, W.J.G., Hurk, P.J.J.C. Van Den, Zoll, J., Galama, J.M.D., Kuppeveld, F.J.M. Van

Demonstration of Mycoplasma contamination in cell cultures by a Mycoplasma group-specific polymerase chain reaction. In G.E. Jones (1996)

Melchers, W.J.G., Johansson, K.-E., Logt, J.T.M., Van Der, Kuppeveld, F.J.M., Van

Genotypic characterization of sequential Aspergillus fumigatus isolates from patients with cystic fibrosis (1996)

Melchers, W.J.G., Latgé, J.-P., Hoogkamp-Korstanje, J.A.A., Sarfati, J., Verweij, P.E., Meis, J.F.G.M.

Human papilloma virus detection by in situ hybridisation signal amplification based on biotinylated tyramine deposition (1996)

Hanselaar, A.G.J.M., Melchers, W.J.G., Robben, J.C., Kerstens, H.M.J., Bulten, J., Poddighe, P.J.

Interrepeat fingerprinting of third-generation chephalosporin-resistant Enterobacter cloacae isolated during an outbreak in a neonatal intensive care unit (1995)

Meis, J.F.G.M., Hoogkamp-Korstanje, J.A.A., Voss, A., Melchers, W.J.G., Belkum, A., Van, Verweij, P.E.

Multicenter evaluation of arbitrarily primed PCR for typing of Staphylococcus aureus strains (1995)

Verbrugh, H.A., Tenover, F., Struelens, M., Maes, N., Moonens, F., Vaneechoutte, M., ...

Mycobacterium detection by polymerase chain reaction (1995)

Melchers, W.J.G., Meis, J.F.G.M., Willemse, H.F.M.

PCR-based characterization of Yersinia enterocolitica : comparison with biotyping and serotyping (1995)

Melchers, W.J.G., Hoogkamp-Korstanje, J.A.A., Hurk, P.J.J.C. Van Den, Meis, J.F.G.M., Odinot, P.T.

Phylogenetic relationships of five species of Aspergillus and related taxa as deduced by comparison of sequences of small subunit ribosomal RNA (1995)

Melchers, W.J.G., Samson, R.A., Zoll, G.J., Hurk, P.J.J.C., Van Den, Meis, J.F.G.M., Verweij, P.E.

Risk of cross-colonization and infection by Pseudomonas aeruginosa in a holiday camp for cystic fibrosis patients (1995)

Melchers, W.J.G., Laag, J. Van Der, Kissing, J., Meis, J.F.G.M., Hoogkamp-Korstanje, J.A.A.

Severe human psittacosis requiring artificial ventilation: case report and review (1995)

Galama, J.M.D., Melchers, W.J.G., Eijk, R.J.R., Meis, J.F.G.M., Verweij, P.E.

Severe human psittacosis requiring artificial ventilation: case report and review. (1995)

Galama, J.M.D., Melchers, W.J.G., Eijk, R.J.R., Meis, J.F.G.M., Verweij, P.E.

Study of treatment of congenital Toxoplasma gondii infection in rhesus monkeys with pyramethamine and sulfadiazine (1995)

Melchers, W.J.G., Meuwissen, J.H.E.T., Eskes, T.K.A.B., Camps, W., Baars, A.M., Vree, T.B., ...

Study of treatment of congenital Toxoplasma gondii infection in rhesus monkeys with pyrimethamine and sulfadiazine (1995)

Meuwissen, J.H.E.T., Melchers, W.J.G., Eskes, T.K.A.B., Baars, A.M., Camps, W., Vree, T.B., ...

Study of treatment of congenital sulfadiazine (1995)

Meuwissen, J.H.E.T., Melchers, W.J.G., Eskes, T.K.A.B., Baars, A.M., Camps, W., Vree, T.B., ...

Study of treatment of congenital toxoplasma gondii infection in rhesus monkeys with pyrimethamine and sulfadiazine (1995)

Melchers, W.J.G., Meuwissen, J.H.E.T., Eskes, T.K.A.B., Baars, A.M., Camps, W., Vree, T.B., ...

Characterization of verocytotoxin-producing Escherichia coli 0157 isolated from patients with haemolytic uraemic syndrome in Western Europe (1995)

Melchers, W.J.G., Monnens, L.A.H., Meis, J.F.G.M., Kar, N.C.A.J. Van De, Heuvelink, A.E.

Characterization of verocytotoxin-producing Escherichia coli 0157 isolates from patients with hemolytic uremic syndrome in Western Europe (1995)

Melchers, W.J.G., Monnens, L.A.H., Kar, N.C.A.J., Van De, Meis, J.F.G.M., Heuvelink, A.E.

Comparison of antigen detection and PCR assay using bronchoalveolar lavage fluid for diagnosing invasive pulmonary aspergillosis in patients receiving treatment for hematological malignancies (1995)

Meis, J.F.G.M., Hoogkamp-Korstanje, J.A.A., Pauw, B.E. De, Melchers, W.J.G., Latgé, J.-P., Rijs, A.J.M.M., ...

Epidemiology survey of an outbreak of multiresistant Serratia marcescens by PCR-fingerprinting. (1995)

Meis, J.F.G.M., Hoogkamp-Korstanje, J.A.A., Voss, A., Melchers, W.J.G., Debast, S.

Genetic analysis of a hydrophobic domain of Coxsackie B3 virus protein 2B : a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis (1995)

Melchers, W.J.G., Zoll, J., Galama, J.M.D., Kuppeveld, F.J.M. Van

In vitro effects of sulfadiazine and its metabolites alone and in combination with pyrimethamine on Toxoplasma gondii (1995)

Galama, J.M.D., Camps, W., Melchers, W.J.G., Vree, T.B., Schoondermark-van De Ven, E.M.E.

Enteroviruses and the chronic fatigue syndrome (1994)

Meer, J.W.M. Van Der, Swanink, C.M.A., Melchers, W.J.G., Galama, J.M.D., Fennis, J.F.M., Bleijenberg, G., ...

Isolation and Characterization of Verocytotoxin-Producing Escherichia coli O157 Strains from Dutch Cattle and Sheep

Heuvelink, A. E., Van Den Biggelaar, F. L. A. M., De Boer, E., Herbes, R. G., Melchers, W. J. G., Huis In ’t Veld, J. H. J., ...

In the periods from July to November 1995 and 1996, fecal samples from Dutch cattle and sheep were collected at the main slaughterhouses of The Netherlands, located at different geographic sites. The...

Occurrence of Verocytotoxin-Producing Escherichia coli O157 on Dutch Dairy Farms

Heuvelink, A. E., Van Den Biggelaar, F. L. A. M., Zwartkruis-Nahuis, J. T. M., Herbes, R. G., Huyben, R., Nagelkerke, N., ...

During the period from September 1996 through November 1996, 10 Dutch dairy farms were visited to collect fecal samples from all cattle present. The samples were examined for the presence of...

Human papilloma virus detection by in situ hybridisation signal amplification based on biotinylated tyramine deposition

Poddighe, P J, Bulten, J, Kerstens, H M J, Robben, J C M, Melchers, W J G, Hanselaar, A G J M

Aim—To describe a method for amplifying human papilloma virus (HPV) in situ hybridisation (ISH) signals.

Toxoplasmosis after Renal Transplantation: Implications of a Missed Diagnosis

Wulf, M. W. H., Van Crevel, R., Portier, R., Ter Meulen, C. G., Melchers, W. J. G., Van Der Ven, A., ...

We describe a renal transplant patient with a primary Toxoplasma gondii infection presenting as pneumonitis, with subsequent chorioretinitis and encephalitis. The diagnostic challenges of T. gondii...

Isolation and Characterization of Verocytotoxin-Producing Escherichia coli O157 Strains from Dutch Cattle and Sheep

Heuvelink, A. E., Van Den Biggelaar, F. L. A. M., De Boer, E., Herbes, R. G., Melchers, W. J. G., Huis In ’t Veld, J. H. J., ...

In the periods from July to November 1995 and 1996, fecal samples from Dutch cattle and sheep were collected at the main slaughterhouses of The Netherlands, located at different geographic sites. The...

Occurrence of Verocytotoxin-Producing Escherichia coli O157 on Dutch Dairy Farms

Heuvelink, A. E., Van Den Biggelaar, F. L. A. M., Zwartkruis-Nahuis, J. T. M., Herbes, R. G., Huyben, R., Nagelkerke, N., ...

During the period from September 1996 through November 1996, 10 Dutch dairy farms were visited to collect fecal samples from all cattle present. The samples were examined for the presence of...

Human papilloma virus detection by in situ hybridisation signal amplification based on biotinylated tyramine deposition

Poddighe, P J, Bulten, J, Kerstens, H M J, Robben, J C M, Melchers, W J G, Hanselaar, A G J M

Aim—To describe a method for amplifying human papilloma virus (HPV) in situ hybridisation (ISH) signals.

Toxoplasmosis after Renal Transplantation: Implications of a Missed Diagnosis

Wulf, M. W. H., Van Crevel, R., Portier, R., Ter Meulen, C. G., Melchers, W. J. G., Van Der Ven, A., ...

We describe a renal transplant patient with a primary Toxoplasma gondii infection presenting as pneumonitis, with subsequent chorioretinitis and encephalitis. The diagnostic challenges of T. gondii...

Ventilator-Associated Pneumonia Caused by Dolosigranulum pigrum

Hoedemaekers, A., Schülin, T., Tonk, B., Melchers, W. J. G., Sturm, P. D. J.

Dolosigranulum pigrum is an unusual gram-positive catalase-negative coccus. It was isolated, only after prolonged incubation, from bronchial secretions from a patient with ventilator-associated...

A New Aspergillus fumigatus Resistance Mechanism Conferring In Vitro Cross-Resistance to Azole Antifungals Involves a Combination of cyp51A Alterations▿

Mellado, E., Garcia-Effron, G., Alcázar-Fuoli, L., Melchers, W. J. G., Verweij, P. E., Cuenca-Estrella, M., ...

Fourteen Aspergillus fumigatus clinical isolates that exhibited a pattern of reduced susceptibility to triazole drugs were analyzed. The sequences of the cyp51A gene from all isolates showed the...

Multicenter Comparison of Molecular Methods for Detection of Legionella spp. in Sputum Samples▿

Bencini, M. A., Van Den Brule, A. J. C., Claas, E. C. J., Hermans, M. H. A., Melchers, W. J. G., Noordhoek, G. T., ...

Legionellosis can be diagnosed by PCR using sputum samples. In this report, the methods of nine laboratories for 12 sputum samples with Legionella pneumophila and Legionella longbeachae are compared....