W. J. Lech

In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects.

Lech, W J, Wang, G, Yang, Y L, Chee, Y, Dorman, K, McCrae, D, ...

We have evaluated the sequence diversity of the protease human immunodeficiency virus type 1 in vivo. Our analysis of 246 protease coding domain sequences obtained from 12 subjects indicates that...

Rapid evolution of human immunodeficiency virus strains with increased replicative capacity during the seronegative window of primary infection.

Ferbas, J, Daar, E S, Grovit-Ferbas, K, Lech, W J, Detels, R, Giorgi, J V, ...

The relationship between host and virus was examined during the initial stages of human immunodeficiency virus type 1 (HIV) infection in a volunteer from the Multicenter AIDS Cohort Study (MACS). The...

In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects.

Lech, W J, Wang, G, Yang, Y L, Chee, Y, Dorman, K, McCrae, D, ...

We have evaluated the sequence diversity of the protease human immunodeficiency virus type 1 in vivo. Our analysis of 246 protease coding domain sequences obtained from 12 subjects indicates that...

Rapid evolution of human immunodeficiency virus strains with increased replicative capacity during the seronegative window of primary infection.

Ferbas, J, Daar, E S, Grovit-Ferbas, K, Lech, W J, Detels, R, Giorgi, J V, ...

The relationship between host and virus was examined during the initial stages of human immunodeficiency virus type 1 (HIV) infection in a volunteer from the Multicenter AIDS Cohort Study (MACS). The...