W. J. Welch

Publication List Details

Period

1997 - 2006

Number

63

Co-Authors

8.35 MM RADIO EMISSION FROM JUPITER AND VENUS, (2006)

Thornton,D.D., Welch,W.J.

Observations of the 8.35 mm radio emission from Jupiter and Venus are reported. A disc temper ature of 144 = 23 deg. is found for Jupiter and a temperature of 383 = 60 deg. is found for Venus. It is...

Molecular Abundances in B68 (2002)

Di Francesco, J., Hogerheijde, M. R., Welch, W. J., Bergin, E. A.

Abundances for C18O, CS, NH3, H2CO, C3H2, and N2H+ and upper limits for the abundances of 13CO and HCO+ are derived for gas within the Bok globule B68 using our own BIMA array data, single-dish data...

Broadband Amplitude Calibration of the ATA (2002)

W. J. Welch, D. C. -j. Bock

A planar equiangular spiral antenna can provide the calibration signal for the ATA antenna. The spiral antenna is located on the primary of the ATA antenna near its edge. It is fed by a broadband...

Spatially Resolved Millimeter Spectroscopy of the Gravitational Lens PKS 1830-211 (2001)

Swift, J., Welch, W. J., Frye, B.

This paper presents data from the BIMA interferometer showing spatially resolved absorption spectra of the gravitationally lensed quasar PKS 1830-211. High-resolution (1.2 km/s) spectra were taken in...

Unveiling the Circumstellar Envelope and Disk: A Sub-Arcsecond Survey of Circumstellar Structures (1999)

Looney, Leslie W., Mundy, Lee G., Welch, W. J.

We present the results of a 2.7 mm continuum interferometric survey of 24 young stellar objects in 11 fields. The target objects range from deeply embedded Class 0 sources to optical T Tauri sources....

STUDY OF FREQUENCY INDEPENDENT ANTENNAS (1999)

RUMSEY, V. H., WELCH, W. J., BORGIOTTI, G., GANS, M. J., SUSSMAN, R.

An investigation was made of frequency-independent antenn fro the point of view of designing the antennas for any radiation pattern and polarization. Solutions of Maxwell's equations were discovered...

A Solution to the Frequency-Independent Antenna Problem (1999)

Cheo, B. R., Rumsey, V. H., Welch, W. J.

A solution of Maxwell's equations is obtained for an antenna consisting of an infinite number of equally spaced wires in the form of coplanar equiangular spirals. Radiation amplitude patterns...

A SOLUTION TO THE FREQUENCY-INDEPENDENT ANTENNA PROBLEM (1998)

CHEO,B., RUMSEY,V.H., WELCH,W.J.

A solution of Maxwell's equations is obtained for an antenna consisting of an infinite number of equally spaced wires in the form of coplanar equiangular spirals. Radiation amplitude patterns...

A MEASUREMENT OF THE COSMIC MICROWAVE BACKGROUND TEMPERATURE AT 1.5 CM. WAVELENGTH. (1998)

Welch,W. J., Keachie,S., Thornton,D. D., Wrixon,G.

This report discusses the measurement of the cosmic microwave background temperature at 1.5 cm. wavelength; the result is 2.0 plus or minus 0.8 degrees K. Experimental techniques and the sources of...

UPPER LIMITS ON LIQUID WATER IN THE VENUS ATMOSPHERE. (1998)

Welch,W. J., Rea,D. C.

The purpose of the report is to point out one consequence of the discovery of HCl and HF in the Venus atmosphere, namely, that on account of the presence of HCl there cannot be much liquid water in...

SOLAR EMISSION AND ACTIVITY IN THE FREQUENCY REGION 18 TO 36 GIGACYCLES. (1998)

El Raey,Mohammed, Silver,S., Welch,W. J.

The spectral distribution of solar radiation and the characteristics of solar activity have been studied intensively and may be considered well known in the megacycle region of the spectrum....

Phase correction for the BIMA array: atmospherical model calculations for the design of a prototype correlation radiometer (1998)

J. Staguhn, A. I. Harris, R. L. Plambeck, W. J. Welch

We present results from atmospheric model calculations for the design of an atmospheric phase correlation radiometer for the Berkeley-Illinois-Maryland Millimeter Array (BIMA). The radiometer will...

High Resolution $\lambda$ = 2.7 mm Observations of L1551 IRS5: A Protobinary System? (1997)

Looney, Leslie W., Mundy, Lee G., Welch, W. J.

We present sub-arcsecond resolution imaging of the $\lambda$ = 2.7 mm continuum emission from the young, embedded system L1551 IRS5 using the nine-element, high-resolution configuration of the BIMA...

Scrapie prions selectively modify the stress response in neuroblastoma cells.

Tatzelt, J, Zuo, J, Voellmy, R, Scott, M, Hartl, U, Prusiner, S B, ...

The fundamental event underlying scrapie infection seems to be a conformational change in the prion protein. To investigate proteins that might feature in the conversion of the cellular prion protein...

Nitric oxide synthase in macula densa regulates glomerular capillary pressure.

Wilcox, C S, Welch, W J, Murad, F, Gross, S S, Taylor, G, Levi, R, ...

Tubular-fluid reabsorption by specialized cells of the nephron at the junction of the ascending limb of the loop of Henle and the distal convoluted tubule, termed the macula densa, releases compounds...

Interaction of hsp70 with unfolded proteins: effects of temperature and nucleotides on the kinetics of binding.

Palleros, D R, Welch, W J, Fink, A L

Circular dichroism and HPLC gel filtration were used to show that cytosolic hsp70 is thermally stable but undergoes a conformational transition (midpoint, 43 degrees C; 57 degrees C in the presence...

Amino-terminal sequence analysis of alphavirus polypeptides.

Welch, W J, Sefton, B M, Esch, F S

The single late 26S mRNA of Semliki Forest virus (SFV) directs the synthesis of the four viral structural proteins, C, E3, E2, and E1, and the recently described nonstructural protein, 6K. We report...

Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein.

Walter, G, Carbone, A, Welch, W J

Affinity-purified medium T antigen encoded by NG59, a nontransforming mutant of polyomavirus, is specifically associated with a protein of 72,000 daltons (72K protein). Medium T antigens of wild-type...

Complexes between nascent polypeptides and their molecular chaperones in the cytosol of mammalian cells.

Eggers, D K, Welch, W J, Hansen, W J

Folding of newly synthesized proteins in vivo is believed to be facilitated by the cooperative interaction of a defined group of proteins known as molecular chaperones. We investigated the direct...

Mitogen and lymphokine stimulation of heat shock proteins in T lymphocytes.

Ferris, D K, Harel-Bellan, A, Morimoto, R I, Welch, W J, Farrar, W L

We have examined the effects of phytohemagglutinin (PHA) and the polypeptide growth factor interleukin 2 (IL-2) on the synthesis of the 70- and 90-kDa heat shock proteins (HSP70 and HSP90,...

Characterization of a small, nonstructural viral polypeptide present late during infection of BHK cells by Semliki Forest virus.

Welch, W J, Sefton, B M

BHK cells, late in infection with Semliki Forest virus, were found to contain a small virus-specific polypeptide not found in the mature virion. This polypeptide had an apparent molecular weight of...

Clinical implications of the stress response.

Minowada, G, Welch, W J

A field of research that began with a curious observation in Drosophila has resulted in a new understanding of how cells respond to sudden and adverse changes in their environment. In addition...

Potentiation of tubuloglomerular feedback in the rat by thromboxane mimetic. Role of macula densa.

Welch, W J, Wilcox, C S

Because endogenous thromboxane A2 (TXA2) potentiates the tubuloglomerular feedback response (TGF), we studied the mechanism of action of TXA2 by using a stable TXA2/prostaglandin (PG) H2 mimetic,...

Vesicular stomatitis virus glycoprotein is anchored in the viral membrane by a hydrophobic domain near the COOH terminus

Rose, J. K., Welch, W. J., Sefton, B. M., Esch, F. S., Ling, N. C.

We have determined the COOH-terminal and NH2-terminal amino acid sequences of the vesicular stomatitis virus (VSV) glycoprotein (G). A sequence of 122 COOH-terminal amino acids was deduced from the...

Two small virus-specific polypeptides are produced during infection with Sindbis virus.

Welch, W J, Sefton, B M

We have identified and characterized two small virus-specific polypeptides which are produced during infection of cells with Sindbis virus, but which are not incorporated into the mature virion. The...

The two mammalian mitochondrial stress proteins, grp 75 and hsp 58, transiently interact with newly synthesized mitochondrial proteins.

Mizzen, L A, Kabiling, A N, Welch, W J

In mammalian cells, two of the so-called heat shock (hsp) or stress proteins are components of the mitochondria. One of these, hsp 58, is a member of the bacterial GroEL family, whereas the other,...

Binding of heat shock proteins to the avian progesterone receptor.

Kost, S L, Smith, D F, Sullivan, W P, Welch, W J, Toft, D O

The protein composition of the avian progesterone receptor was analyzed by immune isolation of receptor complexes and gel electrophoresis of the isolated proteins. Nonactivated cytosol receptor was...

Dynamic changes in the structure and intracellular locale of the mammalian low-molecular-weight heat shock protein.

Arrigo, A P, Suhan, J P, Welch, W J

Mammalian cells grown at 37 degrees C contain a single low-molecular-weight heat shock (or stress) protein with an apparent mass of 28 kilodaltons (kDa) whose synthesis increases in cells after...

Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides.

Welch, W J, Feramisco, J R

A new and rapid purification procedure has been developed for the mammalian 70,000-dalton (70-kDa) heat-shock (or stress) proteins. Both the constitutive 73-kDa protein and the stress-induced 72-kDa...

Disruption of the three cytoskeletal networks in mammalian cells does not affect transcription, translation, or protein translocation changes induced by heat shock.

Welch, W J, Feramisco, J R

Mammalian cells show a complex series of transcriptional and translational switching events in response to heat shock treatment which ultimately lead to the production and accumulation of a small...

Modulating role for thromboxane in the tubuloglomerular feedback response in the rat.

Welch, W J, Wilcox, C S

Some studies have indicated that PGs can modulate the single nephron tubuloglomerular feedback (TGF) response. The aim of this study was to define the specific role of the vasoconstrictor PG, TX, by...

Chemical chaperones interfere with the formation of scrapie prion protein.

Tatzelt, J, Prusiner, S B, Welch, W J

The fundamental event in prion diseases involves a conformational change in one or more of the alpha-helices of the cellular prion protein (PrP(C)) as they are converted into beta-sheets during the...

Correcting temperature-sensitive protein folding defects.

Brown, C R, Hong-Brown, L Q, Welch, W J

Recently, we found that different low molecular weight compounds, all known to stabilize proteins in their native conformation, are effective in correcting the temperature-sensitive protein folding...

Macula densa arginine delivery and uptake in the rat regulates glomerular capillary pressure. Effects of salt intake.

Welch, W J, Wilcox, C S

These studies tested the hypothesis that delivery and/or cellular uptake of L-arginine limits macula densa nitric oxide generation and actions on tubuloglomerular feedback (TGF) during salt...

The common 90-kd protein component of non-transformed '8S' steroid receptors is a heat-shock protein.

Catelli, M G, Binart, N, Jung-Testas, I, Renoir, J M, Baulieu, E E, Feramisco, J R, ...

Non-transformed steroid receptors have an approximately 8S sedimentation coefficient that corresponds to an oligomeric structure of 250-300 kd which includes a non-hormone binding 90-kd protein. A...

Scrapie prions selectively modify the stress response in neuroblastoma cells.

Tatzelt, J, Zuo, J, Voellmy, R, Scott, M, Hartl, U, Prusiner, S B, ...

The fundamental event underlying scrapie infection seems to be a conformational change in the prion protein. To investigate proteins that might feature in the conversion of the cellular prion protein...

Nitric oxide synthase in macula densa regulates glomerular capillary pressure.

Wilcox, C S, Welch, W J, Murad, F, Gross, S S, Taylor, G, Levi, R, ...

Tubular-fluid reabsorption by specialized cells of the nephron at the junction of the ascending limb of the loop of Henle and the distal convoluted tubule, termed the macula densa, releases compounds...

Interaction of hsp70 with unfolded proteins: effects of temperature and nucleotides on the kinetics of binding.

Palleros, D R, Welch, W J, Fink, A L

Circular dichroism and HPLC gel filtration were used to show that cytosolic hsp70 is thermally stable but undergoes a conformational transition (midpoint, 43 degrees C; 57 degrees C in the presence...

Amino-terminal sequence analysis of alphavirus polypeptides.

Welch, W J, Sefton, B M, Esch, F S

The single late 26S mRNA of Semliki Forest virus (SFV) directs the synthesis of the four viral structural proteins, C, E3, E2, and E1, and the recently described nonstructural protein, 6K. We report...

Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein.

Walter, G, Carbone, A, Welch, W J

Affinity-purified medium T antigen encoded by NG59, a nontransforming mutant of polyomavirus, is specifically associated with a protein of 72,000 daltons (72K protein). Medium T antigens of wild-type...

Complexes between nascent polypeptides and their molecular chaperones in the cytosol of mammalian cells.

Eggers, D K, Welch, W J, Hansen, W J

Folding of newly synthesized proteins in vivo is believed to be facilitated by the cooperative interaction of a defined group of proteins known as molecular chaperones. We investigated the direct...

Mitogen and lymphokine stimulation of heat shock proteins in T lymphocytes.

Ferris, D K, Harel-Bellan, A, Morimoto, R I, Welch, W J, Farrar, W L

We have examined the effects of phytohemagglutinin (PHA) and the polypeptide growth factor interleukin 2 (IL-2) on the synthesis of the 70- and 90-kDa heat shock proteins (HSP70 and HSP90,...

Characterization of a small, nonstructural viral polypeptide present late during infection of BHK cells by Semliki Forest virus.

Welch, W J, Sefton, B M

BHK cells, late in infection with Semliki Forest virus, were found to contain a small virus-specific polypeptide not found in the mature virion. This polypeptide had an apparent molecular weight of...

Clinical implications of the stress response.

Minowada, G, Welch, W J

A field of research that began with a curious observation in Drosophila has resulted in a new understanding of how cells respond to sudden and adverse changes in their environment. In addition...

Potentiation of tubuloglomerular feedback in the rat by thromboxane mimetic. Role of macula densa.

Welch, W J, Wilcox, C S

Because endogenous thromboxane A2 (TXA2) potentiates the tubuloglomerular feedback response (TGF), we studied the mechanism of action of TXA2 by using a stable TXA2/prostaglandin (PG) H2 mimetic,...

Vesicular stomatitis virus glycoprotein is anchored in the viral membrane by a hydrophobic domain near the COOH terminus

Rose, J. K., Welch, W. J., Sefton, B. M., Esch, F. S., Ling, N. C.

We have determined the COOH-terminal and NH2-terminal amino acid sequences of the vesicular stomatitis virus (VSV) glycoprotein (G). A sequence of 122 COOH-terminal amino acids was deduced from the...

Two small virus-specific polypeptides are produced during infection with Sindbis virus.

Welch, W J, Sefton, B M

We have identified and characterized two small virus-specific polypeptides which are produced during infection of cells with Sindbis virus, but which are not incorporated into the mature virion. The...

The two mammalian mitochondrial stress proteins, grp 75 and hsp 58, transiently interact with newly synthesized mitochondrial proteins.

Mizzen, L A, Kabiling, A N, Welch, W J

In mammalian cells, two of the so-called heat shock (hsp) or stress proteins are components of the mitochondria. One of these, hsp 58, is a member of the bacterial GroEL family, whereas the other,...

Binding of heat shock proteins to the avian progesterone receptor.

Kost, S L, Smith, D F, Sullivan, W P, Welch, W J, Toft, D O

The protein composition of the avian progesterone receptor was analyzed by immune isolation of receptor complexes and gel electrophoresis of the isolated proteins. Nonactivated cytosol receptor was...

Dynamic changes in the structure and intracellular locale of the mammalian low-molecular-weight heat shock protein.

Arrigo, A P, Suhan, J P, Welch, W J

Mammalian cells grown at 37 degrees C contain a single low-molecular-weight heat shock (or stress) protein with an apparent mass of 28 kilodaltons (kDa) whose synthesis increases in cells after...

Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides.

Welch, W J, Feramisco, J R

A new and rapid purification procedure has been developed for the mammalian 70,000-dalton (70-kDa) heat-shock (or stress) proteins. Both the constitutive 73-kDa protein and the stress-induced 72-kDa...

Disruption of the three cytoskeletal networks in mammalian cells does not affect transcription, translation, or protein translocation changes induced by heat shock.

Welch, W J, Feramisco, J R

Mammalian cells show a complex series of transcriptional and translational switching events in response to heat shock treatment which ultimately lead to the production and accumulation of a small...

Modulating role for thromboxane in the tubuloglomerular feedback response in the rat.

Welch, W J, Wilcox, C S

Some studies have indicated that PGs can modulate the single nephron tubuloglomerular feedback (TGF) response. The aim of this study was to define the specific role of the vasoconstrictor PG, TX, by...

Chemical chaperones interfere with the formation of scrapie prion protein.

Tatzelt, J, Prusiner, S B, Welch, W J

The fundamental event in prion diseases involves a conformational change in one or more of the alpha-helices of the cellular prion protein (PrP(C)) as they are converted into beta-sheets during the...

Correcting temperature-sensitive protein folding defects.

Brown, C R, Hong-Brown, L Q, Welch, W J

Recently, we found that different low molecular weight compounds, all known to stabilize proteins in their native conformation, are effective in correcting the temperature-sensitive protein folding...

Macula densa arginine delivery and uptake in the rat regulates glomerular capillary pressure. Effects of salt intake.

Welch, W J, Wilcox, C S

These studies tested the hypothesis that delivery and/or cellular uptake of L-arginine limits macula densa nitric oxide generation and actions on tubuloglomerular feedback (TGF) during salt...

The common 90-kd protein component of non-transformed '8S' steroid receptors is a heat-shock protein.

Catelli, M G, Binart, N, Jung-Testas, I, Renoir, J M, Baulieu, E E, Feramisco, J R, ...

Non-transformed steroid receptors have an approximately 8S sedimentation coefficient that corresponds to an oligomeric structure of 250-300 kd which includes a non-hormone binding 90-kd protein. A...

Stress preconditioning attenuates oxidative injury to the alveolar epithelium of the lung following haemorrhage in rats

Pittet, J F, Lu, L N, Geiser, T, Lee, H, Matthay, M A, Welch, W J

Inhibition of cAMP-dependent stimulation of vectorial fluid transport across the alveolar epithelium following haemorrhagic shock is mediated by reactive nitrogen species released within the...