W. L. Ford

Duration of the inductive effect of sheep erythrocytes on the recruitment of lymphocytes in the rat

Ford, W. L.

The serum haemolysin response was studied in rats which had been subjected to a suppressive whole-body dose of γ-irradiation followed after 24 hours by an intravenous injection of sheep...

The effects of interferon on the recirculation of lymphocytes in the rat.

Kimber, I, Sparshott, S M, Bell, E B, Ford, W L

Lymphocytes from the thoracic duct (TDL) were incubated with interferon (IFN) prior to i.v. injection into syngeneic or allogeneic recipient rats. The effect of IFN treatment on the ability of...

The carriage and delivery of substances to lymphatic tissues by recirculating lymphocytes. II. Long-term selective irradiation of the spleen and lymph nodes by deposition of indium-114m.

Birch, M, Sharma, H L, Bell, E B, Ford, W L

Recirculating lymphocytes were used to carry an isotope of indium, In-114m. The isotope has a half-life of 50 days, and emits both gamma and beta particles, properties that may be useful clinically....

The carriage and delivery of substances to lymphatic tissues by recirculating lymphocytes. I. The concentration of ricin in lymphocyte traffic areas.

Sparshott, S M, Forrester, J A, McIntosh, D P, Wood, C, Davies, A J, Ford, W L

Thoracic duct lymphocytes (TDL) were loaded in vitro with ricin before intravenous injection into syngeneic rats. TDL that had been incubated at 10 micrograms of ricin/5 X 10(7) cells/ml migrated...

The recirculating lymphocyte pool of the rat: a systematic description of the migratory behaviour of recirculating lymphocytes.

Smith, M E, Ford, W L

A comprehensive study of lymphocyte traffic in AO rats was performed under conditions as near to the physiological state as was practicable. In the light of previous results on the effect of...

The rapid rejection of allogeneic lymphocytes by a non-adaptive, cell-mediated mechanism (NK activity).

Rolstad, B, Fossum, S, Bazin, H, Kimber, I, Marshall, J, Sparshott, S M, ...

The fate of allogeneic lymphocytes (AO or DA) transferred to non-immune PVG recipients was studied in the light of previous evidence (Heslop & McNeilage, 1983; Rolstad & Ford, 1983) that allogeneic...

The sequence of changes in blood flow and lymphocyte influx to stimulated rat lymph nodes.

Drayson, M T, Smith, M E, Ford, W L

The rat popliteal lymph node was studied from 1 hr to 8 days after the footpad injection of either sheep erythrocytes or syngeneic rat erythrocytes. The following were measured relative to the...

A venue-based method for sampling hard-to-reach populations.

Muhib, F. B., Lin, L. S., Stueve, A., Miller, R. L., Ford, W. L., Johnson, W. D., ...

Constructing scientifically sound samples of hard-to-reach populations, also known as hidden populations, is a challenge for many research projects. Traditional sample survey methods, such as random...

The significance of changes in blood lymphocyte populations following surgical operations.

Hamid, J, Bancewicz, J, Brown, R, Ward, C, Irving, M H, Ford, W L

After surgery blood lymphocyte levels fell to one-third of the pre-operative value. Since this depression was transient, and followed the peak of serum cortisol closely, it was probably due to a...

Human lymphocyte traffic assessed by indium-111 oxine labelling: clinical observations.

Wagstaff, J, Gibson, C, Thatcher, N, Ford, W L, Sharma, H, Crowther, D

Clinical studies using indium-111 oxine labelling of human peripheral blood lymphocytes are presented. Data from animal models of lymphocyte migration are compared with results found in healthy...

A method for following human lymphocyte traffic using indium-111 oxine labelling.

Wagstaff, J, Gibson, C, Thatcher, N, Ford, W L, Sharma, H, Benson, W, ...

A method is described whereby large numbers of human lymphocytes are separated from peripheral blood and labelled in vitro with indium-111 oxine. Following autologous reinjection, the distribution...

An experimental comparison of radioactive labels with potential application to lymphocyte migration studies in patients.

Rannie, G H, Thakur, M L, Ford, W L

The suitability of two radionuclides (99mTc, 111In) for labelling lymphocytes have been evaluated in rats by comparison with a standard method using 51Cr. For the study of lymphocyte migration in...

The recruitment of recirculating lymphocytes in the antigenically stimulated spleen: specific and non-specific consequences of initiating a secondary antibody response

Ford, W. L.

Antigenic stimulation of the rat spleen to initiate a secondary response to tetanus toxoid (tet. tox.) has been found to have two effects on the recirculating lymphocytes which are migrating through...

THE SPECIFIC SELECTION OF RECIRCULATING LYMPHOCYTES BY ANTIGEN IN NORMAL AND PREIMMUNIZED RATS

Rowley, D. A., Gowans, J. L., Atkins, R. C., Ford, W. L., Smith, Marilyn E.

Thoracic duct lymphocytes (TDL) from normal rats will restore a primary antibody response to sheep erythrocytes (SRBC) in irradiated recipients and cause a graft-versus-host reaction in F1 hybrid...