Ho, D W, Field, P R, Irving, W L, Packham, D R, Cunningham, A L
Western blots (immunoblots) for the detection of immunoglobulin M (IgM) antibodies specific for herpes simplex virus type 1 (HSV-1) and HSV-2 in patients' sera were developed. The locations of the...
Serological diagnosis of infection with human herpesvirus type 6.
OBJECTIVE--To identify clinical consequences of acute human herpesvirus type 6 infection by hypothesising that the virus will induce similar clinical syndromes to cytomegalovirus. DESIGN--Examination...
Ho, D W, Field, P R, Irving, W L, Packham, D R, Cunningham, A L
Western blots (immunoblots) for the detection of immunoglobulin M (IgM) antibodies specific for herpes simplex virus type 1 (HSV-1) and HSV-2 in patients' sera were developed. The locations of the...
Serological diagnosis of infection with human herpesvirus type 6.
OBJECTIVE--To identify clinical consequences of acute human herpesvirus type 6 infection by hypothesising that the virus will induce similar clinical syndromes to cytomegalovirus. DESIGN--Examination...
Irving, W L, Walker, P R, Lydyard, P M
Blood lymphocytes from 53 patients with rheumatoid arthritis (RA) and 44 controls were cultured with the polyclonal B cell activator Epstein-Barr virus (EBV). Culture supernatants were removed at...
Evidence for B cell activation in patients with active rheumatoid arthritis.
Youinou, P Y, Irving, W L, Shipley, M, Hayes, J, Lydyard, P M
Peripheral blood lymphocytes and in some cases synovial eluate cells from 51 patients with rheumatoid arthritis (RA), were analysed for the percentages of cells bearing surface light chains (total B...
Atta, M S, Irving, W L, Powell, R J, Todd, I
Certain viruses are known to modulate the cellular expression of MHC molecules. We have investigated whether reovirus types 1 or 3 can alter the normal MHC molecule expression on cultured human...
Al-Sakkaf, L, Pozzilli, P, Sensi, M, Irving, W L, Bottazzo, G F
A study has been undertaken to differentiate T cytotoxic (Tc) and T suppressor (Ts) cell subsets using a monoclonal antibody termed H366 (mouse IgG2b) previously reported to phenotype natural killer...
Brown, K S, Keogh, M J, Tagiuri, N, Grainge, M J, Presanis, J S, Ryder, S D, ...
Mannan-binding lectin (MBL) binds microorganisms via interactions with glycans on the target surface. Bound MBL subsequently activates MBL-associated serine protease proenzymes (MASPs). A role for...
Ball, J. K., Rowe, T., Curran, R., Irving, W. L., Beards, G. M., Sontag, G., ...
OBJECTIVES: The long term effectiveness of combination therapy at reducing viral loads in seminal fluid and blood plasma obtained from HIV-1 infected men who had undergone previous antiretroviral...
Roseola infantum and other syndromes associated with acute HHV6 infection.
Irving, W L, Chang, J, Raymond, D R, Dunstan, R, Grattan-Smith, P, Cunningham, A L
Eight cases of acute human herpesvirus type 6 (HHV6) infection in infants were diagnosed serologically by the demonstration of IgM anti-HHV6 (8/8) and a significant change in total anti-HHV6 antibody...