W. Lems

Publication List Details

Period

1968 - 2006

Number

36

Co-Authors

The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destruction (2006)

GEUSENS, Pieter [1196], Landewe, R., Garnero, P., Chen, D., Dunstan, C., Lems, W., ...

Rheumatoid arthritis (RA) is a chronic inflammatory disease that may result in debilitating joint deformities with destruction of bone and cartilage. Inflammation is still considered the pivotal...

Review and evaluation of the Dutch guidelines for osteoporosis (2006)

GEUSENS, Pieter [1196], Lems, W., Verhaar, H., Leusink, G., Goemaere, S., Zmierczack, H., ...

Rationale At the request of a Dutch governmental organization, a multidisciplinary group of osteoporosis experts in the Netherlands published in 2002 a guideline on case finding, diagnosis,...

Positive effect of alendronate on bone mineral density and markers of bone turnover in patients with rheumatoid arthritis on chronic treatment with low-dose prednisone: a randomized, double-blind, placebo-controlled trial. (2006)

Lems, W., Lodder, M., Lips, P., Bijlsma, J., GEUSENS, Pieter [1196], Schrameijer, N., ...

Alendronate has been described to have a bone-sparing effect in patients treated with moderate and high dosages of prednisone for heterogeneous diseases, however no data are available on groups of...

The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destruction (2006)

GEUSENS, Pieter [1196], Landewe, R., Garnero, P., Chen, D., Dunstan, C., Lems, W., ...

Rheumatoid arthritis (RA) is a chronic inflammatory disease that may result in debilitating joint deformities with destruction of bone and cartilage. Inflammation is still considered the pivotal...

Review and evaluation of the Dutch guidelines for osteoporosis (2006)

GEUSENS, Pieter [1196], Lems, W., Verhaar, H., Leusink, G., Goemaere, S., Zmierczack, H., ...

Rationale At the request of a Dutch governmental organization, a multidisciplinary group of osteoporosis experts in the Netherlands published in 2002 a guideline on case finding, diagnosis,...

Positive effect of alendronate on bone mineral density and markers of bone turnover in patients with rheumatoid arthritis on chronic treatment with low-dose prednisone: a randomized, double-blind, placebo-controlled trial. (2006)

Lems, W., Lodder, M., Lips, P., Bijlsma, J., GEUSENS, Pieter [1196], Schrameijer, N., ...

Alendronate has been described to have a bone-sparing effect in patients treated with moderate and high dosages of prednisone for heterogeneous diseases, however no data are available on groups of...

Development of antiinfliximab antibodies and relationship to clinical response in patients with rheumatoid arthritis (2006)

Wolbink, G.J., Vis, M. Van Der, Lems, W., Voskuyl, A.E., Groot, E. De, Nurmohamed, M.T., ...

Objective. Treatment of patients with infliximab, a chimeric monoclonal IgG1 antibody against tumor necrosis factor, may result in the formation of infliximab-specific IgG antibodies. This study...

The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destruction (2006)

GEUSENS, Piet, Landewe, R., Garnero, P., Chen, D., Dunstan, C., Lems, W., ...

Rheumatoid arthritis (RA) is a chronic inflammatory disease that may result in debilitating joint deformities with destruction of bone and cartilage. Inflammation is still considered the pivotal...

Review and evaluation of the Dutch guidelines for osteoporosis (2006)

GEUSENS, Piet, Lems, W., Verhaar, H., Leusink, G., Goemaere, S., Zmierczack, H., ...

Rationale At the request of a Dutch governmental organization, a multidisciplinary group of osteoporosis experts in the Netherlands published in 2002 a guideline on case finding, diagnosis,...

Positive effect of alendronate on bone mineral density and markers of bone turnover in patients with rheumatoid arthritis on chronic treatment with low-dose prednisone: a randomized, double-blind, placebo-controlled trial. (2006)

Lems, W., Lodder, M., Lips, P., Bijlsma, J., GEUSENS, Piet, Schrameijer, N., ...

Alendronate has been described to have a bone-sparing effect in patients treated with moderate and high dosages of prednisone for heterogeneous diseases, however no data are available on groups of...

Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritis (2004)

Landewe, R, Boers, M, Lems, W, Koppele, JT, Van Der Linden, S, Garnero, P, ...

Objective. To investigate in a randomized clinical trial setting with an aggressive combination-therapy arm and a mild-monotherapy arm, whether therapy-induced changes in urinary C-terminal...

Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritis (2004)

Landewe, R, Boers, M, Lems, W, Koppele, JT, Van Der Linden, S, Garnero, P, ...

Objective. To investigate in a randomized clinical trial setting with an aggressive combination-therapy arm and a mild-monotherapy arm, whether therapy-induced changes in urinary C-terminal...

MAGNETIZATION REVERSAL OF ELECTRODEPOSITED FeNi FILMS (1968)

Lems, W., Holtwijk, Th.

The magnetization reversal due to an applied pulse field of FeNi films (ca. 3 % Ni), which possess an isotropic square hysteresis loop, is studied. The results obtained on thick films (d > 2 µm) are...

MAGNETIZATION REVERSAL OF ELECTRODEPOSITED FeNi FILMS (1968)

Lems, W., Holtwijk, Th.

The magnetization reversal due to an applied pulse field of FeNi films (ca. 3 % Ni), which possess an isotropic square hysteresis loop, is studied. The results obtained on thick films (d > 2 µm) are...

MAGNETIZATION REVERSAL OF ELECTRODEPOSITED FeNi FILMS (1968)

Lems, W., Holtwijk, Th.

The magnetization reversal due to an applied pulse field of FeNi films (ca. 3 % Ni), which possess an isotropic square hysteresis loop, is studied. The results obtained on thick films (d > 2 µm) are...

Is addition of sodium fluoride to cyclical etidronate beneficial in the treatment of corticosteroid induced osteoporosis?

Lems, W., Jacobs, J., Bijlsma, J., Van Veen, G. J M, Houben, H., Haanen, H., ...

OBJECTIVE—To investigate whether administration of sodium fluoride (NaF) in addition to cyclical etidronate has a positive effect on bone mineral density (BMD) in patients with established...

Systematic review of the cost effectiveness of prophylactic treatments in the prevention of gastropathy in patients with rheumatoid arthritis or osteoarthritis taking non-steroidal anti-inflammatory drugs

Van Dieten, H. E M, Bos, I., Van Tulder, M. W, Lems, W., Dijkmans, B., Boers, M.

A systematic review on the cost effectiveness of prophylactic treatments of non-steroidal anti-inflammatory drug (NSAID) induced gastropathy in patients with osteoarthritis or rheumatoid arthritis...

Data driven attempt to create a clinical algorithm for identification of women with rheumatoid arthritis at high risk of osteoporosis

Kvien, T., Haugeberg, G., Uhlig, T., Falch, J., Halse, J., Lems, W., ...

OBJECTIVES—To examine relations between osteoporosis and low bone mass and demographic and clinical variables in patients with rheumatoid arthritis (RA), in an attempt to develop a data driven...

Outcome of cervical spine surgery in patients with rheumatoid arthritis

Van Asselt, K M, Lems, W, Bongartz, E, Hamburger, H, Drossaers-Bakker, K, Dijkmans, B, ...

OBJECTIVES—Cervical spine instability in patients with rheumatoid arthritis (RA) may lead to cervical myelopathy or occipital neuralgia, or both. Morbidity and mortality in patients with RA treated...

Incidence of clinically manifest ulcers and their complications in patients with rheumatoid arthritis

Steen, K, Lems, W, Aertsen, J, Bezemer, D, Dijkmans, B

BACKGROUND—Non-steroidal anti-inflammatory drugs (NSAIDs) are often prescribed in patients with rheumatoid arthritis (RA). Because of its frequency and severity, NSAID gastropathy is the most...

Acquired resistance of human T cells to sulfasalazine: stability of the resistant phenotype and sensitivity to non-related DMARDs

Van Der Heijden, J, De Jong, M C, Dijkmans, B, Lems, W, Oerlemans, R, Kathmann, I, ...

Background: A recent study from our laboratory showed that induction of the multidrug resistance related drug efflux pump ABCG2 contributed to acquired resistance of human T cells to the disease...

Development of sulfasalazine resistance in human T cells induces expression of the multidrug resistance transporter ABCG2 (BCRP) and augmented production of TNFα

Van Der Heijden, J, De Jong, M C, Dijkmans, B, Lems, W, Oerlemans, R, Kathmann, I, ...

Objective: To determine whether overexpression of cell membrane associated drug efflux pumps belonging to the family of ATP binding cassette (ABC) proteins contributes to a diminished efficacy of...

Reproducibility of bone mineral density measurement in daily practice

Lodder, M, Lems, W, Ader, H, Marthinsen, A, Van Coeverden, S C C M, Lips, P, ...

Background: Bone mineral density (BMD) measurements are frequently performed repeatedly for each patient. Subsequent BMD measurements allow reproducibility to be assessed.

Hand cortical bone mass and its associations with radiographic joint damage and fractures in 50–70 year old female patients with rheumatoid arthritis: cross sectional Oslo-Truro-Amsterdam (OSTRA) collaborative study

Haugeberg, G, Lodder, M, Lems, W, Uhlig, T, Orstavik, R, Dijkmans, B, ...

Methods: Demographic, clinical data, and imaging data on hand radiographs and Genants vertebral deformity score on spine radiographs were collected from 135 women with RA of ⩾5 years, recruited...

Long term high intensity exercise and damage of small joints in rheumatoid arthritis

De Jong, Z, Munneke, M, Zwinderman, A, Kroon, H, Ronday, K, Lems, W, ...

Objective: To investigate the effect of long term high intensity weightbearing exercises on radiological damage of the joints of the hands and feet in patients with rheumatoid arthritis (RA).

Bone mineral density in patients with rheumatoid arthritis: relation between disease severity and low bone mineral density

Lodder, M, De Jong, Z, Kostense, P, Molenaar, E, Staal, K, Voskuyl, A, ...

Objective: To examine variables associated with bone mineral density (BMD) in patients with rheumatoid arthritis (RA).

Relationship between serum trough infliximab levels, pretreatment C reactive protein levels, and clinical response to infliximab treatment in patients with rheumatoid arthritis

Wolbink, G, Voskuyl, A, Lems, W, De Groot, E, Nurmohamed, M, Tak, P, ...

Objective: To investigate the relationship between serum trough infliximab levels and clinical response to infliximab treatment in patients with rheumatoid arthritis (RA).