Pharmacogenetics in rheumatology: the prospects and limitations of an emerging field (2002)
Siva, C., Yokoyama, W. M., McLeod, H. L.
Objectives. To review the fundamental concepts of pharmacogenetics and analyse how the broad principles of this rapidly emerging field may influence the treatment of rheumatic disease in future....
Orihuela, M, Margulies, D H, Yokoyama, W M
Natural killer (NK) cells are inhibited from killing cellular targets by major histocompatibility complex (MHC) class I molecules. In the mouse, this can be mediated by the Ly-49A NK cell receptor...
Bot, A, Reichlin, A, Isobe, H, Bot, S, Schulman, J, Yokoyama, W M, ...
We investigated the role of different lymphocyte subpopulations in the host defense reaction against influenza virus infection, taking advantage of various immunodeficient mouse strains. Whereas,...
Bettler, B, Hofstetter, H, Rao, M, Yokoyama, W M, Kilchherr, F, Conrad, D H
The cDNA encoding the murine low-affinity receptor for IgE (Fc epsilon RII) has been isolated from a cDNA library prepared from B cells activated with lipopolysaccharide and interleukin 4. It encodes...
Thy-1+ dendritic epidermal cells belong to the T-cell lineage.
Stingl, G, Gunter, K C, Tschachler, E, Yamada, H, Lechler, R I, Yokoyama, W M, ...
The murine epidermis contains a population of dendritic, Thy-1+ cells (Thy-1+ DEC). Although it is now clear that these cells are of bone marrow origin, extensive morphological, histochemical, and...
Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain.
Stingl, G, Koning, F, Yamada, H, Yokoyama, W M, Tschachler, E, Bluestone, J A, ...
The murine epidermis is a heterogeneous epithelium composed of keratinocytes, melanocytes, Langerhans cells, and a recently described subpopulation (2-3%) of bone-marrow-derived leukocytes with a...
Orihuela, M, Margulies, D H, Yokoyama, W M
Natural killer (NK) cells are inhibited from killing cellular targets by major histocompatibility complex (MHC) class I molecules. In the mouse, this can be mediated by the Ly-49A NK cell receptor...
Bot, A, Reichlin, A, Isobe, H, Bot, S, Schulman, J, Yokoyama, W M, ...
We investigated the role of different lymphocyte subpopulations in the host defense reaction against influenza virus infection, taking advantage of various immunodeficient mouse strains. Whereas,...
Bettler, B, Hofstetter, H, Rao, M, Yokoyama, W M, Kilchherr, F, Conrad, D H
The cDNA encoding the murine low-affinity receptor for IgE (Fc epsilon RII) has been isolated from a cDNA library prepared from B cells activated with lipopolysaccharide and interleukin 4. It encodes...
Thy-1+ dendritic epidermal cells belong to the T-cell lineage.
Stingl, G, Gunter, K C, Tschachler, E, Yamada, H, Lechler, R I, Yokoyama, W M, ...
The murine epidermis contains a population of dendritic, Thy-1+ cells (Thy-1+ DEC). Although it is now clear that these cells are of bone marrow origin, extensive morphological, histochemical, and...
Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain.
Stingl, G, Koning, F, Yamada, H, Yokoyama, W M, Tschachler, E, Bluestone, J A, ...
The murine epidermis is a heterogeneous epithelium composed of keratinocytes, melanocytes, Langerhans cells, and a recently described subpopulation (2-3%) of bone-marrow-derived leukocytes with a...
The Ly-49D Receptor Activates Murine Natural Killer Cells
Mason, L.H., Anderson, S.K., Yokoyama, W.M., Smith, H.R.C., Winkler-Pickett, R., Ortaldo, J.R.
Proteins encoded by members of the Ly-49 gene family are predominantly expressed on murine natural killer (NK) cells. Several members of this gene family have been demonstrated to inhibit NK cell...