Webster, G F, Leyden, J J, McGinley, K J, McArthur, W P
Propionibacterium acnes is the cause of inflammation in acne vulgaris and has been shown to produce potent neutrophil chemoattractants. Different strain of P. acnes that were sensitive or resistant...
Immune modulation of Prevotella intermedia colonization in squirrel monkeys.
Clark, W B, Magnusson, I, Beem, J E, Jung, J M, Marks, R G, McArthur, W P
Colonization of the gingival crevice by black-pigmented Porphyromonas or Prevotella spp. (BP/P), including Porphyromonas gingivalis (formerly Bacteroides gingivalis) and Prevotella intermedia...
Subgingival microbiota in squirrel monkeys with naturally occurring periodontal diseases.
Beem, J E, Hurley, C G, Magnusson, I, McArthur, W P, Clark, W B
The squirrel monkey (Saimiri sciureus) has been proposed as an in vivo model for the study of subgingival colonization by suspected periodontopathogens, such as black-pigmented porphyromonads and...
Clark, W B, Magnusson, I, Abee, C, Collins, B, Beem, J E, McArthur, W P
The objective of this study was to determine whether the squirrel monkey (Saimiri scuireus) is indigenously colonized with black-pigmented bacteroides (BPB) resembling human Bacteroides gingivalis...
Monoclonal antibodies to Actinobacillus actinomycetemcomitans.
Place, D A, Scidmore, N C, McArthur, W P
Murine hybridoma cell lines were developed which synthesized monoclonal antibodies against Actinobacillus actinomycetemcomitans-associated antigens. Monoclonal antibodies specific for an antigen(s)...
Ayakawa, G Y, Boushell, L W, Crowley, P J, Erdos, G W, McArthur, W P, Bleiweis, A S
A panel of 15 murine monoclonal antibodies (MAbs; 14 immunoglobulin G1, 1 immunoglobulin G2a) directed against antigen P1, a major surface protein of mutans streptococci, was prepared. All of these...
McArthur, W P, Magnusson, I, Marks, R G, Clark, W B
Periodontal diseases are inflammatory responses thought to be triggered by specific microorganisms colonizing in the gingival crevice. Theoretically, periodontal diseases could be prevented if the...
Baehni, P, Tsai, C C, McArthur, W P, Hammond, B F, Taichman, N S
In the present study we identified a gram-negative anaerobic rod referred to as Y4 which was cytotoxic for human polymorphonuclear leukocytes. Y4 was isolated from dental plaque of a patient with...
Tsai, C C, McArthur, W P, Baehni, P C, Hammond, B F, Taichman, N S
The plaque-derived gram-negative microorganism Y4 identified as a member of the genus Actinobacillus, was tested for a soluble cytotoxic factor(s). Sonication or incubation of viable Y4...
The release of lysosomal hydrolases from polymorphonuclear leukocytes (PMNs) has been postulated in the pathogenesis of tissue injury in periodontal disease. In the present study, lysosomal enzyme...
McArthur, W P, Baehni, P, Taichman, N S
In the absence of antiserum, rabbit polymorphonuclear leukocytes (PMNs) released lysosomal enzymes in response to Actinomyces viscosus (19246) but not to Streptococcus mutans (6715). Antibodies had a...
Taichman, N S, Tsai, C C, Baehni, P C, Stoller, N, McArthur, W P
The deposition of bacterial plaques on tooth surfaces appears to be responsible for the initiation and progression of periodontal disease. In this study, human peripheral blood polymorphonuclear...
Biological and Chemical Characterization of Endotoxin from Capnocytophaga sputigena
Stevens, R. H., Sela, M. N., McArthur, W. P., Nowotny, A., Hammond, B. F.
An endotoxin was isolated from Capnocytophaga sputigena strain 4 by a modification of the hot phenol-water method. The extraction procedure yielded a lipopolysaccharide which accounted for...
Webster, G F, Leyden, J J, McGinley, K J, McArthur, W P
Propionibacterium acnes is the cause of inflammation in acne vulgaris and has been shown to produce potent neutrophil chemoattractants. Different strain of P. acnes that were sensitive or resistant...
Immune modulation of Prevotella intermedia colonization in squirrel monkeys.
Clark, W B, Magnusson, I, Beem, J E, Jung, J M, Marks, R G, McArthur, W P
Colonization of the gingival crevice by black-pigmented Porphyromonas or Prevotella spp. (BP/P), including Porphyromonas gingivalis (formerly Bacteroides gingivalis) and Prevotella intermedia...
Subgingival microbiota in squirrel monkeys with naturally occurring periodontal diseases.
Beem, J E, Hurley, C G, Magnusson, I, McArthur, W P, Clark, W B
The squirrel monkey (Saimiri sciureus) has been proposed as an in vivo model for the study of subgingival colonization by suspected periodontopathogens, such as black-pigmented porphyromonads and...
Clark, W B, Magnusson, I, Abee, C, Collins, B, Beem, J E, McArthur, W P
The objective of this study was to determine whether the squirrel monkey (Saimiri scuireus) is indigenously colonized with black-pigmented bacteroides (BPB) resembling human Bacteroides gingivalis...
Monoclonal antibodies to Actinobacillus actinomycetemcomitans.
Place, D A, Scidmore, N C, McArthur, W P
Murine hybridoma cell lines were developed which synthesized monoclonal antibodies against Actinobacillus actinomycetemcomitans-associated antigens. Monoclonal antibodies specific for an antigen(s)...
Ayakawa, G Y, Boushell, L W, Crowley, P J, Erdos, G W, McArthur, W P, Bleiweis, A S
A panel of 15 murine monoclonal antibodies (MAbs; 14 immunoglobulin G1, 1 immunoglobulin G2a) directed against antigen P1, a major surface protein of mutans streptococci, was prepared. All of these...
McArthur, W P, Magnusson, I, Marks, R G, Clark, W B
Periodontal diseases are inflammatory responses thought to be triggered by specific microorganisms colonizing in the gingival crevice. Theoretically, periodontal diseases could be prevented if the...
Baehni, P, Tsai, C C, McArthur, W P, Hammond, B F, Taichman, N S
In the present study we identified a gram-negative anaerobic rod referred to as Y4 which was cytotoxic for human polymorphonuclear leukocytes. Y4 was isolated from dental plaque of a patient with...
Tsai, C C, McArthur, W P, Baehni, P C, Hammond, B F, Taichman, N S
The plaque-derived gram-negative microorganism Y4 identified as a member of the genus Actinobacillus, was tested for a soluble cytotoxic factor(s). Sonication or incubation of viable Y4...
The release of lysosomal hydrolases from polymorphonuclear leukocytes (PMNs) has been postulated in the pathogenesis of tissue injury in periodontal disease. In the present study, lysosomal enzyme...
McArthur, W P, Baehni, P, Taichman, N S
In the absence of antiserum, rabbit polymorphonuclear leukocytes (PMNs) released lysosomal enzymes in response to Actinomyces viscosus (19246) but not to Streptococcus mutans (6715). Antibodies had a...
Taichman, N S, Tsai, C C, Baehni, P C, Stoller, N, McArthur, W P
The deposition of bacterial plaques on tooth surfaces appears to be responsible for the initiation and progression of periodontal disease. In this study, human peripheral blood polymorphonuclear...
Biological and Chemical Characterization of Endotoxin from Capnocytophaga sputigena
Stevens, R. H., Sela, M. N., McArthur, W. P., Nowotny, A., Hammond, B. F.
An endotoxin was isolated from Capnocytophaga sputigena strain 4 by a modification of the hot phenol-water method. The extraction procedure yielded a lipopolysaccharide which accounted for...
Binding of bursal, thymic and splenic lymphocytes to macrophages
Duncan, R. L., McArthur, W. P.
This study was carried out to examine the potential for chicken lymphocytes from the bursa of Fabricius, the thymus and the spleen to interact physically with glass-adherent peripheral blood...
McArthur, W. P., Chapman, J., Thorbecke, G. J.
Specific antisera to chicken thymus and to bursa of Fabricius were obtained in rabbits. After appropriate absorption and dilution all four anti-thymus sera, in the presence of guinea pig C', killed...