Put, W, Geboes, K, Grillet, B, ...
Chemokines are mediators of innate and acquired immunity. CCL18, also designated pulmonary and activation-regulated chemokine (PARC), dendritic cell-derived CC chemokine-1 (DC-CK1), alternative...
Menten, P, Lenaerts, J-P, Put, W, D'Haese, A, ...
Recently, the LD78beta isoform of the CC chemokine macrophage inflammatory protein (MIP)-1alpha was shown to efficiently chemoattract lymphocytes and monocytes and to inhibit infection of mononuclear...
Lenaerts, J-P, Conings, R, Put, W, ...
Liver and activation-regulated chemokine (LARC), also designated macrophage inflammatory protein-3alpha (MIP-3alpha), Exodus, or CCL20, is a C-C chemokine that attracts immature dendritic cells and...
Lenaerts, J-P, Put, W, Conings, R, ...
Chemokines are a family of chemotactic peptides affecting leukocyte migration during the inflammatory response. Post-translational modification of chemokines has been shown to affect their biological...
Put, W, Lenaerts, J-P, ...
Monocyte chemotactic protein-3 (MCP-3) is a pluripotent CC chemokine, attracting most leukocytic cell types. With the use of a sensitive and specific ELISA, MCP-3 was found to be inducible in...
Van Collie, E, Paemen, L, Put, W, Lenaerts, J-P, ...
Monocyte chemotactic protein (MCP)-1 and MCP-2, two closely related CC chemokines, are important mediators of monocyte and lymphocyte migration. These chemokines are secreted by various normal cell...
Monocyte chemotactic protein-1 in proliferative vitreoretinal disorders (1997)
Put, W, Veckeneer, M, ...
PURPOSE: To investigate whether the chemokines monocyte chemotactic protein-1 (MCP-1) and interleukin-8 (IL-8) are involved in the pathogenesis of proliferative vitreoretinal disorders and to study...
There is considerable evidence that Sertoli cell function is controlled not only by hormones, but also by locally produced growth factors and cytokines. To gain more insight into the nature and...
Monocyte chemotactic protein-1 is released during lethal and sublethal bacteremia in baboons (1995)
Put, W, Dejong, I W, Taylor, F B, Hack, C E
The chemokine monocyte chemotactic protein 1 (MCP-1) is a cytokine with chemotactic activity specific for mononuclear phagocytes. To investigate the possible involvement of MCP-1 in the pathogenesis...
Leukocyte recruitment by monocyte chemotactic proteins (MCPs) secreted by human phagocytes (1994)
Put, W, Lenaerts, J-P, Paemen, L
Phagocyte recruitment is an important immunological phenomenon in inflammation and cancer. A large family of selective chemotactic cytokines, designated chemokines, has recently emerged....
Put, W, Arens, S, Lenaerts, J-P, Conings, R, ...
Monocyte chemotactic proteins (MCP) belong to a group of structurally and functionally related factors, called chemokines. To facilitate additional characterization of the recently identified MCP-2,...
Mice pretreated with monoclonal anti-interleukin-6 (IL-6) antibody and then challenged with lipopolysaccharide (LPS), paradoxically develop higher levels of circulating biological IL-6 activity, as...
Uyttenhove, C, Houssiau, F, Put, W, Van Snick, J
Two mouse helper T cell clones that proliferate in response to murine interleukin (IL)-9 could also be grown in conditioned medium of stimulated human connective tissue cells. The activity was not...
Two rat monoclonal antibodies (6B4 and 20F3) against mouse interleukin (IL)-6 were studied for their effects on the generalized Shwartzman reaction and on cytokine production elicited by endotoxin...
Vanlarebeke, N, Put, W, Bracke, M, Depotter, C, ...
Interleukin-1beta (Il-1beta) and interleukin-1alpha (Il-1alpha) were shown to act as motility factors for the human breast carcinoma cell lines SK-BR-3 and ZR-75-1 in vitro. Both cytokines induced...
Bradykinin induces interleukin-6 and synergizes with interleukin-1 (1991)
Lenaerts, J-P, Put, W, ...
Bradykinin was found to induce production of IL-6 in human diploid fibroblasts, as well as in a hepatoma-derived cell line, but not in a human melanoma or an osteosarcoma cell line. With the...
Decock, B, Bertini, R, Conings, R, Lenaerts, J-P, Put, W, ...
Primary cultures of mouse embryonic fibroblasts and confluent monolayers of mouse fibroblastoid cells (L929) were found to secrete a chemotactic factor specific for monocytes. It biological activity...
Interleukin 6 (IL6) is one of the major inflammation-associated cytokines. Elevated serum or tissue levels of IL6 have been reported to occur in several human diseases, including infections of the...
Interleukin 1 induces different cytokines in human fibroblasts (1989)
Schaafsma, M R, Conings, R, Lenaerts, J-P, Put, W, ...
Rega Institute for Medical Research, University of Leuven, Belgium.
Cayphas, S, Van Snick, J, Conings, R, Put, W, Lenaerts, J P, ...
Human fibroblast cultures, when stimulated with interleukin-1 (IL-1) produce a growth factor for B-cell hybridoma and plasmocytoma cell lines. The availability of both a fast-growing and...