W. R. Morton

Macaques immunized with HLA-DR are protected from challenge with simian immunodeficiency virus.

Arthur, L O, Bess, J W, Urban, R G, Strominger, J L, Morton, W R, Mann, D L, ...

Macaques immunized with uninfected human cells have been shown to be protected from challenge with simian immunodeficiency virus (SIV) propagated in human cells. To identify the potential antigens...

Detection of simian immunodeficiency virus (SIV)-specific CD8+ T cells in macaques protected from SIV challenge by prior SIV subunit vaccination.

Kent, S J, Hu, S L, Corey, L, Morton, W R, Greenberg, P D

Vaccines for lentiviruses would ideally induce in the host complete resistance to infection of host cells. However, such sterilizing immunity may be neither readily achievable nor absolutely...

Persistence of simian immunodeficiency virus Mne variants upon transmission.

Chackerian, B, Morton, W R, Overbaugh, J

In macaques infected with a clone of simian immunodeficiency virus (SIV) Mne, viral variants consistently evolve multiple new potential glycosylation sites in the first variable region (V1) prior to...

Variation in simian immunodeficiency virus env is confined to V1 and V4 during progression to simian AIDS.

Overbaugh, J, Rudensey, L M, Papenhausen, M D, Benveniste, R E, Morton, W R

We have monitored changes in the simian immunodeficiency virus (SIV) envelope (env) gene in two macaques which developed AIDS after inoculation with a molecular clone of SIV. As the animals...

Inoculation of baboons and macaques with simian immunodeficiency virus/Mne, a primate lentivirus closely related to human immunodeficiency virus type 2.

Benveniste, R E, Morton, W R, Clark, E A, Tsai, C C, Ochs, H D, Ward, J M, ...

A primate lymphotropic lentivirus was isolated on the human T-cell line HuT 78 after cocultivation of a lymph node from a pig-tailed macaque (Macaca nemestrina) that had died with malignant lymphoma....

Selective replication of simian immunodeficiency virus in a subset of CD4+ lymphocytes.

Gallatin, W M, Gale, M J, Hoffman, P A, Willerford, D M, Draves, K E, Benveniste, R E, ...

Although all CD4+ cells theoretically are at risk for infection by human immunodeficiency viruses or the related simian immunodeficiency viruses found in Old World monkeys, only a small proportion of...

Cytotoxic and proliferative T cell responses in HIV-1-infected Macaca nemestrina.

Kent, S J, Corey, L, Agy, M B, Morton, W R, McElrath, M J, Greenberg, P D

Macaca nemestrina has been described as an animal model for acute HIV-1 infection. This animal, unlike most infected humans, appears to contain HIV-1 replication. Therefore analysis of HIV-1-specific...

Protection of macaques against simian AIDS by immunization with a recombinant vaccinia virus expressing the envelope glycoproteins of simian type D retrovirus.

Hu, S L, Zarling, J M, Chinn, J, Travis, B M, Moran, P A, Sias, J, ...

Simian AIDS (SAIDS) is an endemic disease of macaques that shares many characteristics with AIDS in humans. SAIDS is etiologically linked to infection by a type D retrovirus, SAIDS retrovirus (SRV)....

Experimental infection of pig-tailed macaques (Macaca nemestrina) with Campylobacter cinaedi and Campylobacter fennelliae.

Flores, B M, Fennell, C L, Kuller, L, Bronsdon, M A, Morton, W R, Stamm, W E

Campylobacter cinaedi and C. fennelliae have been associated with proctocolitis, bacteremia, and asymptomatic rectal infection, primarily in homosexual men. To more directly assess the pathogenic...

Macaques immunized with HLA-DR are protected from challenge with simian immunodeficiency virus.

Arthur, L O, Bess, J W, Urban, R G, Strominger, J L, Morton, W R, Mann, D L, ...

Macaques immunized with uninfected human cells have been shown to be protected from challenge with simian immunodeficiency virus (SIV) propagated in human cells. To identify the potential antigens...

Detection of simian immunodeficiency virus (SIV)-specific CD8+ T cells in macaques protected from SIV challenge by prior SIV subunit vaccination.

Kent, S J, Hu, S L, Corey, L, Morton, W R, Greenberg, P D

Vaccines for lentiviruses would ideally induce in the host complete resistance to infection of host cells. However, such sterilizing immunity may be neither readily achievable nor absolutely...

Persistence of simian immunodeficiency virus Mne variants upon transmission.

Chackerian, B, Morton, W R, Overbaugh, J

In macaques infected with a clone of simian immunodeficiency virus (SIV) Mne, viral variants consistently evolve multiple new potential glycosylation sites in the first variable region (V1) prior to...

Variation in simian immunodeficiency virus env is confined to V1 and V4 during progression to simian AIDS.

Overbaugh, J, Rudensey, L M, Papenhausen, M D, Benveniste, R E, Morton, W R

We have monitored changes in the simian immunodeficiency virus (SIV) envelope (env) gene in two macaques which developed AIDS after inoculation with a molecular clone of SIV. As the animals...

Inoculation of baboons and macaques with simian immunodeficiency virus/Mne, a primate lentivirus closely related to human immunodeficiency virus type 2.

Benveniste, R E, Morton, W R, Clark, E A, Tsai, C C, Ochs, H D, Ward, J M, ...

A primate lymphotropic lentivirus was isolated on the human T-cell line HuT 78 after cocultivation of a lymph node from a pig-tailed macaque (Macaca nemestrina) that had died with malignant lymphoma....

Selective replication of simian immunodeficiency virus in a subset of CD4+ lymphocytes.

Gallatin, W M, Gale, M J, Hoffman, P A, Willerford, D M, Draves, K E, Benveniste, R E, ...

Although all CD4+ cells theoretically are at risk for infection by human immunodeficiency viruses or the related simian immunodeficiency viruses found in Old World monkeys, only a small proportion of...

Cytotoxic and proliferative T cell responses in HIV-1-infected Macaca nemestrina.

Kent, S J, Corey, L, Agy, M B, Morton, W R, McElrath, M J, Greenberg, P D

Macaca nemestrina has been described as an animal model for acute HIV-1 infection. This animal, unlike most infected humans, appears to contain HIV-1 replication. Therefore analysis of HIV-1-specific...

Protection of macaques against simian AIDS by immunization with a recombinant vaccinia virus expressing the envelope glycoproteins of simian type D retrovirus.

Hu, S L, Zarling, J M, Chinn, J, Travis, B M, Moran, P A, Sias, J, ...

Simian AIDS (SAIDS) is an endemic disease of macaques that shares many characteristics with AIDS in humans. SAIDS is etiologically linked to infection by a type D retrovirus, SAIDS retrovirus (SRV)....

Experimental infection of pig-tailed macaques (Macaca nemestrina) with Campylobacter cinaedi and Campylobacter fennelliae.

Flores, B M, Fennell, C L, Kuller, L, Bronsdon, M A, Morton, W R, Stamm, W E

Campylobacter cinaedi and C. fennelliae have been associated with proctocolitis, bacteremia, and asymptomatic rectal infection, primarily in homosexual men. To more directly assess the pathogenic...

Retroperitoneal fibromatosis and acquired immunodeficiency syndrome in macaques. Pathologic observations and transmission studies.

Giddens, W. E., Tsai, C. C., Morton, W. R., Ochs, H. D., Knitter, G. H., Blakley, G. A.

A peculiar fibroproliferative syndrome called retroperitoneal fibromatosis (RF) has been observed in Macaca nemestrina, Macaca mulatta, Macaca fascicularis, and Macaca fuscata at the Washington...