Emery, P., Strubin, M., Hofmann, K., Bucher, P., Mach, B., Reith, W.
The RFX DNA binding domain is a novel motif that has been conserved in a growing number of dimeric DNA-binding proteins, having diverse regulatory functions, in eukaryotic organisms ranging from...
Krawczyk, M., Peyraud, N., Rybtsova, N., Masternak, K., Bucher, P., Barras, E., ...
MHC class II (MHC-II) genes are regulated by an enhanceosome complex containing two gene-specific transcription factors, regulatory factor X complex (RFX) and CIITA. These factors assemble on a...
Gönczy, P., Reith, W., Barras, E., Lisowska-Grospierre, B., Griscelli, C., Hadam, M. R., ...
A defect in a trans-regulatory factor which controls major histocompatibility complex class II gene expression is responsible for an inherited form of immunodeficiency with a lack of expression of...
Doeller, C.F., Opitz, B., Krick, C.M., Mecklinger, A., Reith, W.
It is a topic of current interest whether learning in humans relies on the acquisition of abstract rule knowledge (rule-based learning) or whether it depends on superficial item-specific information...
Primary immunodeficiency mutation databases (2001)
Vihinen, M., Arredondo-Vega, F.X., Casanova, J.L., Etzioni, A., Gilliani, S., Hammerstrom, L., ...
Primary immunodeficiency mutation databases (2000)
Vihinen, M., Arredondo-Vega, F.X., Casanova, J.L., Etzioni, A., Giliani, S., Hammarstrom, L., ...
Bereits seit einiger Zeit ist im Versicherungsgewerbe eine nachhaltige Veränderung der Wettbewerbssituation im Gange, die völig neue Lösungsstrategien erfordert. Dies bewog die deutsche...
Multislice diffusion mapping for 3-D evolution of cerebral ischemia in a rat stroke model (1995)
Reith, W., Hasegawa, Yasuhiro, Latour, Lawrence L., Dardzinski, Bernard J., Sotak, Christopher H., Fisher, Marc
Diffusion-weighted magnetic resonance imaging (DWI) can quantitatively demonstrate cerebral ischemia within minutes after the onset of ischemia. The use of a DWI echo-planar multislice technique in...
Reith, W, Siegrist, C A, Durand, B, Barras, E, Mach, B
Transcription of major histocompatibility complex (MHC) class II genes is controlled largely by the conserved promoter elements called the X and Y boxes. We show here that RFX, the X box-binding...
RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom.
Emery, P, Durand, B, Mach, B, Reith, W
Until recently, the RFX family of DNA binding proteins consisted exclusively of four mammalian members (RFX1-RFX4) characterized by a novel highly conserved DNA binding domain. Strong conservation of...
DNA binding properties of a chemically synthesized DNA binding domain of hRFX1.
Cornille, F, Emery, P, Schüler, W, Lenoir, C, Mach, B, Roques, B P, ...
The RFX DNA binding domain (DBD) is a novel highly conserved motif belonging to a large number of dimeric DNA binding proteins which have diverse regulatory functions in eukaryotic organisms, ranging...
A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity.
Emery, P, Strubin, M, Hofmann, K, Bucher, P, Mach, B, Reith, W
The RFX DNA binding domain is a novel motif that has been conserved in a growing number of dimeric DNA-binding proteins, having diverse regulatory functions, in eukaryotic organisms ranging from...
Cloning and functional characterization of mammalian homologues of the COPII component Sec23.
Paccaud, J P, Reith, W, Carpentier, J L, Ravazzola, M, Amherdt, M, Schekman, R, ...
We screened a human cDNA library with a probe derived from a partial SEC23 mouse homologue and isolated two different cDNA clones (hSec23A and hSec23B) encoding proteins of a predicted molecular mass...
Reith, W, Barras, E, Satola, S, Kobr, M, Reinhart, D, Sanchez, C H, ...
The regulation of major histocompatibility complex class II gene expression is directly involved in the control of normal and abnormal immune responses. In humans, HLA-DR, -DQ, and -DP class II...
Identification of Xenopus laevis mRNAs with homology to repetitive sequences.
Hybrid selection translation experiments have been carried out with genomic and cDNA relatives of two repetitive sequence families. On the basis of the in vitro translation products detected, it was...
Regulatory factor-X binding to mutant HLA-DRA promoter sequences.
Hasegawa, S L, Sloan, J H, Reith, W, Mach, B, Boss, J M
The class II genes of the major histocompatibility complex (MHC) encode a family of cell surface glycoproteins that present processed antigen to the T cell receptor. Class II genes are regulated...
Reith, W, Ucla, C, Barras, E, Gaud, A, Durand, B, Herrero-Sanchez, C, ...
RFX1 is a transactivator of human hepatitis B virus enhancer I. We show here that RFX1 belongs to a previously unidentified family of DNA-binding proteins of which we have cloned three members, RFX1,...
Herrero Sanchez, C, Reith, W, Silacci, P, Mach, B
The X box of major histocompatibility complex class II promoters is essential for proper expression of class II genes. Here we show that two distinct protein-DNA complexes (A and B), which exhibit...
Kobr, M, Reith, W, Herrero-Sanchez, C, Mach, B
The regulation of major histocompatibility complex (MHC) class II gene expression is a key feature of the control of normal and abnormal immune responses. In humans, class II alpha - and beta-chain...
Gönczy, P, Reith, W, Barras, E, Lisowska-Grospierre, B, Griscelli, C, Hadam, M R, ...
A defect in a trans-regulatory factor which controls major histocompatibility complex class II gene expression is responsible for an inherited form of immunodeficiency with a lack of expression of...
Siegrist, C A, Durand, B, Emery, P, David, E, Hearing, P, Mach, B, ...
Hepatitis B virus gene expression is to a large extent under the control of enhancer I (EnhI). The activity of EnhI is strictly dependent on the enhancer factor C (EF-C) site, an inverted repeat that...
Bonnafe, E., Touka, M., AitLounis, A., Baas, D., Barras, E., Ucla, C., ...
There are five members of the RFX family of transcription factors in mammals. While RFX5 plays a well-defined role in the immune system, the functions of RFX1 to RFX4 remain largely unknown. We have...
RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency.
Durand, B, Sperisen, P, Emery, P, Barras, E, Zufferey, M, Mach, B, ...
Major Histocompatibility Complex class II (MHC-II) deficiency is a disease of gene regulation that provides a unique opportunity for the genetic dissection of the molecular mechanisms controlling...
Durand, B, Kobr, M, Reith, W, Mach, B
Major histocompatibility complex (MHC) class II deficiency, or bare lymphocyte syndrome (BLS), is a disease of gene regulation. Patients with BLS have been classified into at least three...
Ferdinandusse, S., Kostopoulos, P., Denis, S., Rusch, H., Overmars, H., Dillmann, U., ...
In this report, we describe the first known patient with a deficiency of sterol carrier protein X (SCPx), a peroxisomal enzyme with thiolase activity, which is required for the breakdown of...
Reith, W, Siegrist, C A, Durand, B, Barras, E, Mach, B
Transcription of major histocompatibility complex (MHC) class II genes is controlled largely by the conserved promoter elements called the X and Y boxes. We show here that RFX, the X box-binding...
RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom.
Emery, P, Durand, B, Mach, B, Reith, W
Until recently, the RFX family of DNA binding proteins consisted exclusively of four mammalian members (RFX1-RFX4) characterized by a novel highly conserved DNA binding domain. Strong conservation of...
DNA binding properties of a chemically synthesized DNA binding domain of hRFX1.
Cornille, F, Emery, P, Schüler, W, Lenoir, C, Mach, B, Roques, B P, ...
The RFX DNA binding domain (DBD) is a novel highly conserved motif belonging to a large number of dimeric DNA binding proteins which have diverse regulatory functions in eukaryotic organisms, ranging...
A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity.
Emery, P, Strubin, M, Hofmann, K, Bucher, P, Mach, B, Reith, W
The RFX DNA binding domain is a novel motif that has been conserved in a growing number of dimeric DNA-binding proteins, having diverse regulatory functions, in eukaryotic organisms ranging from...
Cloning and functional characterization of mammalian homologues of the COPII component Sec23.
Paccaud, J P, Reith, W, Carpentier, J L, Ravazzola, M, Amherdt, M, Schekman, R, ...
We screened a human cDNA library with a probe derived from a partial SEC23 mouse homologue and isolated two different cDNA clones (hSec23A and hSec23B) encoding proteins of a predicted molecular mass...
Reith, W, Barras, E, Satola, S, Kobr, M, Reinhart, D, Sanchez, C H, ...
The regulation of major histocompatibility complex class II gene expression is directly involved in the control of normal and abnormal immune responses. In humans, HLA-DR, -DQ, and -DP class II...
Identification of Xenopus laevis mRNAs with homology to repetitive sequences.
Hybrid selection translation experiments have been carried out with genomic and cDNA relatives of two repetitive sequence families. On the basis of the in vitro translation products detected, it was...
Regulatory factor-X binding to mutant HLA-DRA promoter sequences.
Hasegawa, S L, Sloan, J H, Reith, W, Mach, B, Boss, J M
The class II genes of the major histocompatibility complex (MHC) encode a family of cell surface glycoproteins that present processed antigen to the T cell receptor. Class II genes are regulated...
Reith, W, Ucla, C, Barras, E, Gaud, A, Durand, B, Herrero-Sanchez, C, ...
RFX1 is a transactivator of human hepatitis B virus enhancer I. We show here that RFX1 belongs to a previously unidentified family of DNA-binding proteins of which we have cloned three members, RFX1,...
Durand, B, Kobr, M, Reith, W, Mach, B
Major histocompatibility complex (MHC) class II deficiency, or bare lymphocyte syndrome (BLS), is a disease of gene regulation. Patients with BLS have been classified into at least three...
Herrero Sanchez, C, Reith, W, Silacci, P, Mach, B
The X box of major histocompatibility complex class II promoters is essential for proper expression of class II genes. Here we show that two distinct protein-DNA complexes (A and B), which exhibit...
Kobr, M, Reith, W, Herrero-Sanchez, C, Mach, B
The regulation of major histocompatibility complex (MHC) class II gene expression is a key feature of the control of normal and abnormal immune responses. In humans, class II alpha - and beta-chain...
Gönczy, P, Reith, W, Barras, E, Lisowska-Grospierre, B, Griscelli, C, Hadam, M R, ...
A defect in a trans-regulatory factor which controls major histocompatibility complex class II gene expression is responsible for an inherited form of immunodeficiency with a lack of expression of...
Siegrist, C A, Durand, B, Emery, P, David, E, Hearing, P, Mach, B, ...
Hepatitis B virus gene expression is to a large extent under the control of enhancer I (EnhI). The activity of EnhI is strictly dependent on the enhancer factor C (EF-C) site, an inverted repeat that...
Bonnafe, E., Touka, M., AitLounis, A., Baas, D., Barras, E., Ucla, C., ...
There are five members of the RFX family of transcription factors in mammals. While RFX5 plays a well-defined role in the immune system, the functions of RFX1 to RFX4 remain largely unknown. We have...
RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency.
Durand, B, Sperisen, P, Emery, P, Barras, E, Zufferey, M, Mach, B, ...
Major Histocompatibility Complex class II (MHC-II) deficiency is a disease of gene regulation that provides a unique opportunity for the genetic dissection of the molecular mechanisms controlling...
Ferdinandusse, S., Kostopoulos, P., Denis, S., Rusch, H., Overmars, H., Dillmann, U., ...
In this report, we describe the first known patient with a deficiency of sterol carrier protein X (SCPx), a peroxisomal enzyme with thiolase activity, which is required for the breakdown of...
Ulevitch, R. J., Kline, L., Schreiber, R. D., Pingel, J., Amaldi, I., Reith, W., ...
Class I and class II major histocompatibility complex (MHC) gene products are key recognition units in the induction and regulation of the immune response. Expression of class I and class II may be...