W. Rod Hardy

Modification of the Creator recombination system for proteomics applications – improved expression by addition of splice sites (2006)

Colwill, Karen, Wells, Clark D, Elder, Kelly, Goudreault, Marilyn, Hersi, Kadija, Kulkarni, Sarang, ...

Abstract Background Recombinational systems have been developed to rapidly shuttle Open Reading Frames (ORFs) into multiple expression vectors in order to analyze the large number of cDNAs available...

Modification of the Creator recombination system for proteomics applications – improved expression by addition of splice sites

Colwill, Karen, Wells, Clark D, Elder, Kelly, Goudreault, Marilyn, Hersi, Kadija, Kulkarni, Sarang, ...

Modification of the Creator recombination system for proteomics applications – improved expression by addition of splice sites

Colwill, Karen, Wells, Clark D, Elder, Kelly, Goudreault, Marilyn, Hersi, Kadija, Kulkarni, Sarang, ...

Screening for PTB Domain Binding Partners and Ligand Specificity Using Proteome-Derived NPXY Peptide Arrays▿ †

Smith, Matthew J., Hardy, W. Rod, Murphy, James M., Jones, Nina, Pawson, Tony

Modular interaction domains that recognize peptide motifs in target proteins can impart selectivity in signaling pathways. Phosphotyrosine binding (PTB) domains are components of cytoplasmic docking...

Screening for PTB Domain Binding Partners and Ligand Specificity Using Proteome-Derived NPXY Peptide Arrays

Smith, Matthew J., Hardy, W. Rod, Murphy, James M., Jones, Nina, Pawson, Tony

Analysis of a Shc Family Adaptor Protein, ShcD/Shc4, That Associates with Muscle-Specific Kinase▿

Jones, Nina, Hardy, W. Rod, Friese, Matthew B., Jorgensen, Claus, Smith, Matthew J., Woody, Neil M., ...

Shc family proteins serve as phosphotyrosine adaptor molecules in various receptor-mediated signaling pathways. In mammals, three distinct Shc genes have been described that encode proteins...

ShcA signalling is essential for tumour progression in mouse models of human breast cancer

Ursini-Siegel, Josie, Hardy, W Rod, Zuo, Dongmei, Lam, Sonya H L, Sanguin-Gendreau, Virginie, Cardiff, Robert D, ...

To explore the in vivo significance of ShcA during mammary tumorigenesis, we used mice expressing several phosphotyrosine-deficient ShcA alleles under the control of their endogenous promoter. We...