Predictive factors of visual outcome after local resection of choroidal melanoma.
Damato, B. E., Paul, J., Foulds, W. S.
Local resection of choroidal melanomas is not widely performed so that the indications for this operation have not previously been defined statistically. Univariate and multivariate Cox regression...
Risk factors for residual and recurrent uveal melanoma after trans-scleral local resection.
Damato, B E, Paul, J, Foulds, W S
AIMS: The aims of this study were to report local tumour control after trans-scleral local resection of uveal melanoma and to identify risk factors for (i) clinical residual tumour recognised...
Risk factors for metastatic uveal melanoma after trans-scleral local resection.
Damato, B E, Paul, J, Foulds, W S
AIMS: This study reports the metastatic death rate after trans-scleral local resection of uveal melanoma and identifies relevant risk factors. METHODS: Local resection was performed in 332 patients...
EXUDATIVE DIABETIC RETINOPATHY SPONTANEOUS CHANGES AND EFFECTS OF A CORN OIL DIET*
King, R. C., Dobree, J. H., Kok, D'A., Foulds, W. S., Dangerfield, W. G.
Observations on the 32P uptake test.
The results of the 32P uptake test in the diagnosis of intraocular malignancies is presented. The tests were carried out with the use of newly developed eye probe. A quantitative comparison of...
McNaught, E I, Foulds, W S, Johnson, N F
Xenon photocoagulation burns in the rabbit fundus were studied angiographically with fluorescein labelled dextrans of molecular weights in the range 3000 to 150 000. Recent photocoagulation burns...
Abnormal blood viscosity and haemostasis in long-standing retinal vein occlusion.
Trope, G E, Lowe, G D, McArdle, B M, Douglas, J T, Forbes, C D, Prentice, C M, ...
Blood viscosity and several haemostatic factors were measured in 42 patients with long-standing retinal vein occlusion and 33 control subjects. Blood viscosity, haematocrit, plasma viscosity,...
Common causes of blindness and visual handicap in the west of Scotland.
Ghafour, I. M., Allan, D., Foulds, W. S.
An analysis of blind registration forms was made to determine the commonest causes of blindness in the west of Scotland. It was found that the leading causes of blindness in order of frequency of...
Routes of clearance of radioactive water from the rabbit vitreous.
Moseley, H., Foulds, W. S., Allan, D., Kyle, P. M.
The movement of water to and from the vitreous across the retina and pigment epithelium is important in relation to an understanding of such conditions as retinal detachment and its surgical cure,...
Ghafour, I M, Foulds, W S, Allan, D
Visual acuity, colour vision, and contrast sensitivity of diabetic and non-diabetic subjects were measured before, 20 minutes after, and 24 hours after exposure to slit-lamp illumination either alone...
In vitro studies with a pulsed neodymium/YAG laser.
Venkatesh, S, Guthrie, S, Foulds, W S, Lee, W R, Cruickshank, F R, Bailey, R T
The relationships between the destructive effects of Q-switched Nd/YAG laser pulses and a number of experimental parameters were studied for various target materials including in particular excised,...
Thermal lens measurements in the cornea.
Venkatesh, S, Guthrie, S, Cruickshank, F R, Bailey, R T, Foulds, W S, Lee, W R
Q-switched pulses from a neodymium/YAG (yttrium-aluminium-garnet) laser were passed through corneal discs taken from the enucleated eyes of three baboons and four rabbits. The time course of heat...
Assessment of immunological techniques in the diagnosis and prognosis of ocular malignant melanoma.
Cochran, A. J., Foulds, W. S., Damato, B. E., Trope, G. E., Morrison, L., Lee, W. R.
Tests of cell mediated immunity (one and two stage leucocyte migration inhibition assays) and humoural immunity (membrane immunofluorescence and serum effects on leucocyte migration) were done with...
Do we need a retinal pigment epithelium (or choroid) for the maintenance of retinal apposition?
The relative rarity of retinal detachment following extensive surgical resection of choroid and retinal pigment epithelium for choroidal malignant melanoma is discussed in relation to the factors...
Foulds, W S, Allan, D, Moseley, H, Kyle, P M
The rate of transfer of intravitreally injected tritiated water from the mid vitreous to the choroid is significantly increased after depolymerization of vitreous hyaluronic acid by injected...
Green, F D, Ghafour, I M, Allan, D, Barrie, T, McClure, E, Foulds, W S
The Farnsworth-Munsell 100-hue test has been assessed as a screening test for the detection of diabetic retinopathy likely to benefit from laser photocoagulation therapy. Two hundred and thirty-two...
An in-vitro morphological study of Q-switched neodymium/YAG laser trabeculotomy.
Venkatesh, S, Lee, W R, Guthrie, S, Cruickshank, F R, Foulds, W S, Quigley, R J, ...
Laser trabeculotomies produced by directing a pulsed neodymium/YAG laser beam at specimens of human anterior chamber angle obtained post mortem or after enucleation were studied by light microscopy...
Experimental suprachoroidal plombage with a urethane based hydrophilic polymer.
Foulds, W. S., Aitken, D., Lee, W. R.
Small portions of dehydrated hydrophilic polymer (HPU 90, Smith and Nephew) have been inserted into the suprachoroidal space in rabbits to investigate the possible use of suprachoroidal plombage in...
Brightness discrimination and contrast sensitivity in chronic glaucoma--a clinical study.
Teoh, S L, Allan, D, Dutton, G N, Foulds, W S
The visual acuity, the difference in sensitivity of the two eyes to light (brightness ratio), and contrast sensitivity were assessed in 28 patients with chronic open angle glaucoma and compared with...
After experimental retinal detachment in rabbits macrophages are a prominent feature in the subretinal space or within the retina. Two sources for these macrophages are identified. The retinal...
The retinal-pigment epithelial interface.
The interdependence of the outer retina and pigment epithelium is illustrated by the functional changes and structural alterations which occur in each in response to choroidal ischaemia, retinal...
Herpes simplex virus 1 infection upregulates stress protein expression in cultured retinal neurons.
Kennedy, P G, Wakakura, M, Foulds, W S, Clements, G B
The production of a 57K stress protein (StrP) after herpes simplex virus type 1 (HSV-1) infection was examined in cultured neonatal rat retinal cells. StrP expression in individual cells was...
Analysis of mitochondrial DNA in Leber's hereditary optic neuropathy.
Poulton, J, Deadman, M E, Bronte-Stewart, J, Foulds, W S, Gardiner, R M
Twenty-eight patients from 25 maternal lineages with Leber's hereditary optic neuropathy (LHON) were investigated by restriction enzyme analysis for the presence or absence of the point mutation...