Prion protein helix1 promotes aggregation but is not converted into beta-sheet (2006)
Watzlawik, J., Skora, L., Frense, D., Griesinger, C., Zweckstetter, M., Schulz-Schaeffer, W., ...
LPS receptor (CD14): a receptor for phagocytosis of Alzheimer’s amyloid peptide (2005)
Liu, Y., Walter, S., Stagi, M., Cherny, D. I., Letiembre, M., Schulz-Schaeffer, W., ...
The amyloid β peptide 42 (Aβ₄₂) plays a key role in neurotoxicity in Alzheimer’s disease. Mononuclear phagocytes, i.e. microglia, have the potential to clear Aβ by phagocytosis. Recently,...
Bieschke, J., Giese, A., Schulz-Schaeffer, W., Zerr, I., Poser, S., Eigen, M., ...
A definite diagnosis of prion diseases such as Creutzfeldt–Jakob disease (CJD) relies on the detection of pathological prion protein (PrPSc). However, no test for PrPSc in cerebrospinal fluid (CSF)...
Windl, O., Buchholz, M., Neubauer, A., Schulz-Schaeffer, W., Groschup, M., Walter, S., ...
Transmissible mink encephalopathy (TME) is a rare disease of the North American mink, which has never been successfully transmitted to laboratory mice. We generated transgenic mice expressing the...
Bieschke, J., Giese, A., Schulz-Schaeffer, W., Zerr, I., Poser, S., Eigen, M., ...
A definite diagnosis of prion diseases such as Creutzfeldt–Jakob disease (CJD) relies on the detection of pathological prion protein (PrPSc). However, no test for PrPSc in cerebrospinal fluid (CSF)...
Windl, O., Buchholz, M., Neubauer, A., Schulz-Schaeffer, W., Groschup, M., Walter, S., ...
Transmissible mink encephalopathy (TME) is a rare disease of the North American mink, which has never been successfully transmitted to laboratory mice. We generated transgenic mice expressing the...
Samman, I., Schulz-Schaeffer, W, Wohrle, J, Sommer, A, Kretzschmar, H, Hennerici, M
A 68 year old woman with sporadic Creutzfeldt-Jakob disease is described, who neither showed characteristic EEG abnormalities nor a positive test of the neuronal protein 14-3-3 or neuron specific...
Tschampa, H, Neumann, M, Zerr, I, Henkel, K, Schroter, A, Schulz-Schaeffer, W, ...
OBJECTIVES—To describe the clinical presentation of patients with Alzheimer's disease (AD) or dementia with Lewy bodies (DLB) who were suspected of having Creutzfeldt-Jakob disease (CJD) and to...