P53 mutations in human adrenocortical neoplasms (1994)
Reincke, Martin, Karl, M., Travis, W., Mastorakis, G., Allolio, B., Linehan, M., ...
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical...
Clonal Composition of Human Adrenocortical Neoplasms (1994)
Beuschlein, F., Reincke, Martin, Karl, M., Travis, W., Chrousos, G. P., Jaursch-Hancke, C., ...
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations....
Reincke, Martin, Karl, M., Travis, W., Chrousos, G. P.
G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved...
Surgical management of pheochromocytoma with the use of metyrosine.
Perry, R R, Keiser, H R, Norton, J A, Wall, R T, Robertson, C N, Travis, W, ...
Despite recommended preoperative preparation with alpha-adrenergic blockers, severe hemodynamic instability may occur during operations to resect pheochromocytoma. We combined the alpha-blocker...
Surgical management of pheochromocytoma with the use of metyrosine.
Perry, R R, Keiser, H R, Norton, J A, Wall, R T, Robertson, C N, Travis, W, ...
Despite recommended preoperative preparation with alpha-adrenergic blockers, severe hemodynamic instability may occur during operations to resect pheochromocytoma. We combined the alpha-blocker...
The potential role of BAX and BCL-2 expression in diffuse alveolar damage.
Guinee, D., Brambilla, E., Fleming, M., Hayashi, T., Rahn, M., Koss, M., ...
Apoptosis of type II pneumocytes has been identified in diffuse alveolar damage (DAD), is associated with p53 and WAF1 expression, and may be of pathogenetic importance. BAX, a homologue of BCL-2, is...
Association of p53 and WAF1 expression with apoptosis in diffuse alveolar damage.
Guinee, D., Fleming, M., Hayashi, T., Woodward, M., Zhang, J., Walls, J., ...
Little is known about alterations in cell cycle regulatory proteins such as p53 and WAF1 in diffuse alveolar damage (DAD). We hypothesized that up-regulation of p53 and WAF1 in type II pneumocytes in...
Radiological versus histological diagnosis in UIP and NSIP: survival implications
Flaherty, K, Thwaite, E, Kazerooni, E, Gross, B, Toews, G, Colby, T, ...
Background: High resolution computed tomography (HRCT) has an important diagnostic role in idiopathic interstitial pneumonia (IIP). We hypothesised that the HRCT appearance would have an impact on...