Essays on housing supply, land use regulation and regional labour markets (2008)
Rietveld, P. [Promotor]
Essays on housing supply, land use regulation and regional labour markets (2008)
Rietveld, P. [Promotor]
Human USP3 is a chromatin modifier required for S phase progression and genome stability (2007)
Nicassio, F., Corrado, N., Vissers, J. H. A., Areces, L. B., Bergink, S., Marteijn, J. A., ...
Politi, A., Mone, M.J., Houtsmuller, A., Hoogstraten, D., Vermeulen, W., Heinrich, R., ...
Nucleotide excision repair (NER) requires the concerted action of many different proteins that assemble at sites of damaged DNA in a sequential fashion. We have constructed a mathematical model...
Mone, M.J., Bernas, T., Dinant, C., Goedvree, F.A., Manders, E.M.M., Volker, M., ...
Chromatin is the substrate for many processes in the cell nucleus, including transcription, replication, and various DNA repair systems, all of which require the formation of multiprotein machineries...
DNA damage stabilizes interaction of CSB with the transcription elongation machinery. (2004)
Boom, V. Van Den, Citterio, E., Hoogstraten, D., Zotter, A., Cappellen, W.A. Van, Hoeijmakers, J.H.J., ...
The Cockayne syndrome B (CSB) protein is essential for transcription-coupled DNA repair (TCR), which is dependent on RNA polymerase II elongation. TCR is required to quickly remove the cytotoxic...
Okuda, Y., Nishi, R., Ng, J.M.Y., Vermeulen, W., Mori, T., ...
Mammalian cells express two Rad23 homologs, HR23A and HR23B, which have been implicated in regulation of proteolysis via the ubiquitin/proteasome pathway. Recently, the proteins have been shown to...
Giglia-Mari, G., Coin, F., Ranish, J.A., Hoogstraten, D., Theil, A., Wijgers, N., ...
DNA repair-deficient trichothiodystrophy (TTD) results from mutations in the XPD and XPB subunits of the DNA repair and transcription factor TFIIH. In a third form of DNA repair-deficient TTD, called...
DNA damage stabilizes interaction of CSB with the transcription elongation machinery (2004)
Boom, V. Van Den, Citterio, E., Hoogstraten, D., Zotter, A., Egly, J.M., Cappellen, W.A., ...
The Cockayne syndrome B (CSB) protein is essential for transcription-coupled DNA repair (TCR), which is dependent on RNA polymerase II elongation. TCR is required to quickly remove the cytotoxic...
Agterbosch, S., Vermeulen, W., Glasbergen, P.
This paper analyses the differences in performance of the different types of wind power entrepreneurs now active on the wind power supply market in the Netherlands. The development of the market is...
Ng, M.Y., Vermeulen, W., Sugasawa, K., Vrieling, H., Hoeijmakers, J.H.J.
Primary DNA damage sensing in mammalian global genome nucleotide excision repair (GG-NER) is performed by the xeroderma pigmentosum group C (XPC)/HR23B protein complex. HR23B and HR23A are human...
Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions. (2003)
Rademakers, S., Volker, M., Hoogstraten, D., Nigg, A.L., Mon?, M., Zeeland, A.A. Van, ...
Nucleotide excision repair (NER) is the main DNA repair pathway in mammals for removal of UV-induced lesions. NER involves the concerted action of more than 25 polypeptides in a coordinated fashion....
Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions (2003)
Rademakers, S., Volker, M., Hoogstraten, D., Nigg, A.L., Mone, M.J., Zeeland, A.A. Van, ...
Nucleotide excision repair (NER) is the main DNA repair pathway in mammals for removal of UV-induced lesions. NER involves the concerted action of more than 25 polypeptides in a coordinated fashion....
A Confocal Single Molecule Study of DNA Repair Complexes (2002)
Wyman, C., Wijgers, N., Vermeulen, W., Lenferink, A.T.M., Hoeijmakers, J.H.J., ...
Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage. (2002)
Essers, J., Houtsmuller, A.B., Veelen, L.. Van, Nigg, A.L., Pastink, A.., Vermeulen, W., ...
Recombination between homologous DNA molecules is essential for the proper maintenance and duplication of the genome, and for the repair of exogenously induced DNA damage such as double-strand...
Rapid switching of TFIIH between DNA repair and transcription in living cells. (2002)
Hoogstraten, D., Nigg, A.L., Mullenders, L.H.F., Driel, R. Van, Hoeijmakers, J.H.J., Vermeulen, W., ...
The transcription/repair factor TFIIH operates as a DNA helix opener in RNA polymerase II (RNAP2) transcription and nucleotide excision repair. To study TFIIH in vivo, we generated cell lines...
Segers-Nolten, G.M., Wyman, C., Wijgers, N., Vermeulen, W., Lenferink, A.T., Hoeijmakers, J.H.J., ...
We used scanning confocal fluorescence microscopy to observe and analyze individual DNA- protein complexes formed between human nucleotide excision repair (NER) proteins and model DNA substrates. For...
Segers-Nolten, G.M., Wyman, C., Wijgers, N., Vermeulen, W., Lenferink, A.T., Hoeijmakers, J.H., ...
We used scanning confocal fluorescence microscopy to observe and analyze individual DNA- protein complexes formed between human nucleotide excision repair (NER) proteins and model DNA substrates. For...
Sequential assembly of the nucleotide excision repair factors in vivo. (2001)
Volker, M., Mone, M.J., Karmakar, P., Hoffen, A. Van, Schul, W., Vermeulen, W., ...
A Single Molecule Study on Nucleotide Excision Repair Complexes (2001)
Wyman, C., Wijgers, N., Vermeulen, W., Lenferink, A.T.M., Otto, C., ...
Single nucleotide excision repair complexes studied with confocal fluorescence microscopy (2001)
Wyman, C., Wijgers, N., Vermeulen, W., Lenferink, A.T.M., Otto, C., ...
A temperature-sensitive disorder in basal transcription and DNA repair in man (2001)
Vermeulen, W., Rademakers, S., Jaspers, N.G.J., Appeldoorn, E., Raams, A., Klein, B., ...
The xeroderma pigmentosum group D (XPD) helicase subunit of TFIIH functions in DNA repair and transcription initiation. Different mutations in XPD give rise to three ultraviolet-sensitive syndromes:...
Sequential assembly of nucleotide excision repair factors in vivo. (2001)
Volker, M., Moné, M.J., Karmakar, P., Schul, W., Vermeulen, W., Hoeijmakers, J.H.J., ...
Here, we describe the assembly of the nucleotide excision repair (NER) complex in normal and repair-deficient (xeroderma pigmentosum) human cells, employing a novel technique of local UV irradiation...
Winkler, G.S., Araújo, S.J., Fiedler, U., Vermeulen, W., Coin, F., J-M. Egly, ...
TFIIH is a multisubunit protein complex involved in RNA polymerase II transcription and nucleotide excision repair, which removes a wide variety of DNA lesions including UV-induced photoproducts....
Nakatsu, Y., Asahina, H., Citterio, E., Rademakers, S., Vermeulen, W., Kamiuchi, S., ...
Nucleotide excision repair is a highly versatile DNA repair system responsible for elimination of a wide variety of lesions from the genome. It is comprised of two subpathways: transcription-coupled...
Seroz, T., Winkler, G.S., Auriol, J., Verhage, R.A., Vermeulen, W., Smit, B., ...
Nucleotide excision repair (NER) removes UV-induced photoproducts and numerous other DNA lesions in a highly conserved 'cut-and-paste' reaction that involves approximately 25 core components. In...
Citterio, E., Boom, V. Van Den, Schnitzler, G., Kanaar, R., Bonte, E., Kingston, R.E., ...
The Cockayne syndrome B protein (CSB) is required for coupling DNA excision repair to transcription in a process known as transcription-coupled repair (TCR). Cockayne syndrome patients show UV...
Vermeulen, W., Bergmann, E., Auriol, J., Rademakers, S., Frit, P., Appeldoorn, E., ...
The repair-deficient form of trichothiodystrophy (TTD) most often results from mutations in the genes XPB or XPD, encoding helicases of the transcription/repair factor TFIIH. The genetic defect in a...
Winkler, G.S., Araujo, S.J., Fiedler, U., Vermeulen, W., Coin, F., Egly, J.M., ...
TFIIH is a multisubunit protein complex involved in RNA polymerase II transcription and nucleotide excision repair, which removes a wide variety of DNA lesions including UV-induced photoproducts....
Citterio, E., Boom, V. Van Den, Schnitzler, G., Kanaar, R., Bonte, E., Kingston, R.E., ...
The Cockayne syndrome B protein (CSB) is required for coupling DNA excision repair to transcription in a process known as transcription-coupled repair (TCR). Cockayne syndrome patients show UV...
Seroz, T., Hoeijmakers, J.H., Winkler, G.S., Auriol, J., Verhage, R.A., Vermeulen, W., ...
Nucleotide excision repair (NER) removes UV-induced photoproducts and numerous other DNA lesions in a highly conserved 'cut-and-paste' reaction that involves approximately 25 core components. In...
DNA protein interactions: single molecule spectroscopy and imaging (1999)
Garcia Parajo, M.F., Rademakers, S., Vermeulen, W., Lenferink, A.T.M., Otto, C., ...
DNA-protein interactions: single molecule spectroscopy and imaging (1999)
Garcia Parajo, M.F., Rademakers, S., Vermeulen, W., Lenferink, A.T.M., Otto, C., ...
Action of DNA repair endonuclease ERCC1/XPF in living cells. (1999)
Houtsmuller, A.B., Rademakers, S., Nigg, A.L., Hoogstraten, D., Hoeijmakers, J.H.J., Vermeulen, W.
To study the nuclear organization and dynamics of nucleotide excision repair (NER), the endonuclease ERCC1/XPF (for excision repair cross complementation group 1/xeroderma pigmentosum group F) was...
Winkler, G.S., Vermeulen, W., Coin, F., Egly, J-M., Hoeijmakers, J.H.J., Weeda, G.
TFIIH is a high molecular weight complex with a remarkable dual function in nucleotide excision repair and initiation of RNA polymerase II transcription. Mutations in the largest subunits, the XPB...
Molecular basis of DNA repair mechanisms and syndromes. (1998)
Weeda, G., De Boer, J., Donker, I., De Wit, J., Winkler, S.B., ...
Citterio, E., Rademakers, S., Gool, A.J. Van, Hoeijmakers, J.H.J., Vermeulen, W.
Cockayne syndrome (CS) is a nucleotide excision repair disorder characterized by sun (UV) sensitivity and severe developmental problems. Two genes have been shown to be involved: CSA and CSB. Both...
DNA repair, cancer and aging. (1998)
Hoeijmakers, J.H.J., Weeda, G., Boer, J. De, Sugasawa, K., Vermeulen, W., ...
Winkler, G.S., Vermeulen, W., Coin, F., Egly, J.M., Hoeijmakers, J.H., Weeda, G.
TFIIH is a high molecular weight complex with a remarkable dual function in nucleotide excision repair and initiation of RNA polymerase II transcription. Mutations in the largest subunits, the XPB...
Citterio, E., Rademakers, S., Gool, A.J. Van, Hoeijmakers, J.H., Vermeulen, W.
Cockayne syndrome (CS) is a nucleotide excision repair disorder characterized by sun (UV) sensitivity and severe developmental problems. Two genes have been shown to be involved: CSA and CSB. Both...
In this report the development of an artificial neural network, capable of predicting the temperature after the last finishing stand of a hot strip mill for a certain class of steels, is described....
Vermeulen, W., Morris, P., De Weijer, T.
Continuous cooling transformation (CCT) diagrams play an important role in the description of the transformation behaviour of steels. The experimental determination of a CCT diagram is a very time...
Marinoni, J.C., Roy, R., Vermeulen, W., Miniou, P., Lutz, Y., Weeda, G., ...
TFIIH is a multiprotein factor involved in transcription and DNA repair and is implicated in DNA repair/transcription deficiency disorders such as xeroderma pigmentosum, Cockayne syndrome and...
Weeda, G., Eveno, E., Donker, I., Vermeulen, W., Chevalier-Lagente, O., Taieb, A., ...
Trichothiodystrophy (TTD) is a rare, autosomal recessive disorder characterized by sulfur-deficient brittle hair and nails, mental retardation, impaired sexual development, and ichthyosis....
Weeda, G., Rossignol, M., Fraser, R.A., Winkler, G.S., Vermeulen, W., ...
Mutations in the basal transcription initiation/DNA repair factor TFIIH are responsible for three human disorders: xeroderma pigmentosum (XP), cockayne syndrome (CS) and trichothiodystrophy (TTD)....
Recombining DNA damage repair, basal transcription and human syndromes. (1997)
Hoeijmakers, J.H.J., Weeda, G., Vermeulen, W., Winkler, G.S., Boer, J. De, ...
Gool, A.J. Van, Citterio, E., Rademakers, S., Os, R. Van, Vermeulen, W., Constantinou, A., ...
Transcription-coupled repair (TCR), a subpathway of nucleotide excision repair (NER) defective in Cockayne syndrome A and B (CSA and CSB), is responsible for the preferential removal of DNA lesions...
Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP. (1997)
Vichi, P., Coin, F., J-P. Renaud, Vermeulen, W., Hoeijmakers, J.H.J., Moras, D., ...
A connection between transcription and DNA repair was demonstrated previously through the characterization of TFIIH. Using filter binding as well as in vitro transcription challenge competition...
Mammalian nucleotide excision repair and syndromes. (1997)
Vermeulen, W., Boer, J. De, Citterio, E., Gool, A.J. Van, Jaspers, N.G.J., ...
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway. (1996)
Wang, X.W., Vermeulen, W., Coursen, J.D., Gibson, M., Lupold, S.E., Forrester, K., ...
The molecular pathway of p53-dependent apoptosis (programmed cell death) is poorly understood. Because p53 binds to the basal transcription-repair complex TFIIH and modulates its DNA helicase...
Abrogation of p53-induced apoptosis by the hepatitis B virus X gene. (1996)
Wang, X.W., Gibson, M.K., Vermeulen, W., Yeh, H., Forrester, K., ...
The p53 tumor suppressor gene product is a transcriptional transactivator and a potent apoptotic inducer. The fact that many of the DNA tumor virus oncoproteins bind to p53 and affect these p53...
Hwang, J.R., Moncollin, V., Vermeulen, W., Seroz, T., Vuuren, H. Van, Hoeijmakers, J.H.J., ...
XPB is a subunit of the basal transcription factor TFIIH, which is also involved in nucleotide excision repair (NER) and potentially in cell cycle regulation. A frameshift mutation in the 3'-end of...
TFIIH: a key component in multiple DNA transactions (1996)
Hoeijmakers, J.H.J., Vermeulen., W.
The transcription factor TFIIH is a versatile, multi-functional protein complex with multiple engagements. Apart from its role in basal transcription, TFIIH is intimately implicated in DNA repair and...