The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions (2007)
Merchant, Sabeeha S., Prochnik, Simon E., Vallon, Olivier, Harris, Elizabeth H., Karpowicz, Steven J., Witman, George B., ...
Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as...
The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions (2007)
Merchant, Sabeeha S., Prochnik, Simon E., Vallon, Olivier, Harris, Elizabeth H., Karpowicz, Steven J., Witman, George B., ...
Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as...
The Mother Centriole Plays an Instructive Role in Defining Cell Geometry (2007)
Jessica L. Feldman, Stefan Geimer, Wallace F. Marshall
Centriole positioning is a key step in establishment and propagation of cell geometry, but the mechanism of this positioning is unknown. The ability of pre-existing centrioles to induce formation of...
The Chlamydomonas genome reveals the evolution of key animal and plant functions. (2007)
Merchant, Sabeeha S., Prochnik, Simon E., Vallon, Olivier, Harris, Elizabeth H., Karpowicz, Steven J., Witman, George B., ...
Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as...
Quantitative modeling in cell biology: what is it good for? Dev Cell (2006)
Alex Mogilner, Roy Wollman, Wallace F. Marshall
Recently, there has been a surge in the number of pioneering studies combining experiments with quantitative modeling to explain both relatively simple modules of molecular machinery of the cell and...
De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia (2005)
Shigenori Nonaka, Satoko Yoshiba, Daisuke Watanabe, Shingo Ikeuchi, Tomonobu Goto, Wallace F. Marshall, ...
Left-right asymmetry in the developing mouse embryo is established by leftward fluid flow. Here the authors demonstrate how a posterior tilt of beating cilia creates this unidirectional fluid flow.
De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia (2005)
Shigenori Nonaka, Satoko Yoshiba, Daisuke Watanabe, Shingo Ikeuchi, Tomonobu Goto, Wallace F. Marshall, ...
In the developing mouse embryo, leftward fluid flow on the ventral side of the node determines left–right (L-R) asymmetry. However, the mechanism by which the rotational movement of node cilia can...
Zamora, Ivan, Marshall, Wallace F
Abstract Background The role of centrioles in mitotic spindle function remains unclear. One approach to investigate mitotic centriole function is to ask whether mutation of centriole-associated...
Wallace F. Marshall, John F. Marko, David A. Agard, John W. Sedat
itude of the polar ejection force exerted on chromosome arms during metaphase by individual microtubules. We find Current Biology 2001, 11:569--578 the magnitude of this force to be approximately 1...
Jennifer C. Fung, Wallace F. Marshall, Abby Dernburg, David A. Agard, John W. Sedat, Address John, ...
Abstract. The dynamics by which homologous chromosomes pair is currently unknown. Here, we use fluorescence in situ hybridization in combination with three-dimensional optical microscopy to show that...
Hank W. Bass, Wallace F. Marshall, John W. Sedat, David A. Agard, W. Zacheus C
Abstract. We have analyzed the progressive changes in the spatial distribution of telomeres during meiosis using three-dimensional, high resolution fluorescence microscopy. Fixed meiotic cells of...
Hank W. Bass, Wallace F. Marshall, John W. Sedat, David A. Agard, W. Zacheus C
We have analyzed the progressive changes in the spatial distribution of telomeres during meiosis using three-dimensional, high resolution fluorescence microscopy.
Marshall, Wallace F., Qin, Hongmin, Brenni, Mónica Rodrigo, Rosenbaum, Joel L.
Flagellar length regulation provides a simple model system for addressing the general problem of organelle size control. Based on a systems-level analysis of flagellar dynamics, we have proposed a...
Stolc, Viktor, Samanta, Manoj Pratim, Tongprasit, Waraporn, Marshall, Wallace F.
The important role that cilia and flagella play in human disease creates an urgent need to identify genes involved in ciliary assembly and function. The strong and specific induction of...
De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia
Nonaka, Shigenori, Yoshiba, Satoko, Watanabe, Daisuke, Ikeuchi, Shingo, Goto, Tomonobu, Marshall, Wallace F, ...
In the developing mouse embryo, leftward fluid flow on the ventral side of the node determines left–right (L-R) asymmetry. However, the mechanism by which the rotational movement of node cilia can...
Marshall, Wallace F., Qin, Hongmin, Brenni, Mónica Rodrigo, Rosenbaum, Joel L.
Flagellar length regulation provides a simple model system for addressing the general problem of organelle size control. Based on a systems-level analysis of flagellar dynamics, we have proposed a...
Stolc, Viktor, Samanta, Manoj Pratim, Tongprasit, Waraporn, Marshall, Wallace F.
The important role that cilia and flagella play in human disease creates an urgent need to identify genes involved in ciliary assembly and function. The strong and specific induction of...
De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia
Nonaka, Shigenori, Yoshiba, Satoko, Watanabe, Daisuke, Ikeuchi, Shingo, Goto, Tomonobu, Marshall, Wallace F, ...
In the developing mouse embryo, leftward fluid flow on the ventral side of the node determines left–right (L-R) asymmetry. However, the mechanism by which the rotational movement of node cilia can...
The Mother Centriole Plays an Instructive Role in Defining Cell Geometry
Feldman, Jessica L, Geimer, Stefan, Marshall, Wallace F
Centriole positioning is a key step in establishment and propagation of cell geometry, but the mechanism of this positioning is unknown. The ability of pre-existing centrioles to induce formation of...
Fung, Jennifer C., Marshall, Wallace F., Dernburg, Abby, Agard, David A., Sedat, John W.
The dynamics by which homologous chromosomes pair is currently unknown. Here, we use fluorescence in situ hybridization in combination with three-dimensional optical microscopy to show that...
Bass, Hank W., Marshall, Wallace F., Sedat, John W., Agard, David A., Cande, W. Zacheus
We have analyzed the progressive changes in the spatial distribution of telomeres during meiosis using three-dimensional, high resolution fluorescence microscopy. Fixed meiotic cells of maize (Zea...
Marshall, Wallace F., Rosenbaum, Joel L.
A central question in cell biology is how cells determine the size of their organelles. Flagellar length control is a convenient system for studying organelle size regulation. Mechanistic models...
The cell biological basis of ciliary disease
Defects in cilia cause a broad spectrum of human diseases known collectively as the ciliopathies. Although all ciliopathies arise from defective cilia, the range of symptoms can vary significantly,...
Control of organelle abundance is a fundamental unsolved problem in cell biology. Mechanisms for number control have been proposed in which organelle assembly is actively increased or decreased to...
Modeling Recursive RNA Interference
An important application of the RNA interference (RNAi) pathway is its use as a small RNA-based regulatory system commonly exploited to suppress expression of target genes to test their function in...
Rasi, M. Qasim, Parker, Jeremy D.K., Feldman, Jessica L., Marshall, Wallace F., Quarmby, Lynne M.
Katanin is a microtubule-severing protein that participates in the regulation of cell cycle progression and in ciliary disassembly, but its precise role is not known for either activity. Our data...
Keller, Lani C., Geimer, Stefan, Romijn, Edwin, Yates, John, Zamora, Ivan, Marshall, Wallace F.
Centrioles are intriguing cylindrical organelles composed of triplet microtubules. Proteomic data suggest that a large number of proteins besides tubulin are necessary for the formation and...