Wallace W. Tourtellotte

Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis (2003)

Tajouri, Lotfi, Mellick, Albert, Ashton, Kevin John, Tannenberg, Anthony E.G., Nagra, Rashed M., Tourtellotte, Wallace W., ...

Multiple sclerosis (MS) is a complex autoimmune disorder of the CNS with both genetic and environmental contributing factors. Clinical symptoms are broadly characterized by initial onset, and...

Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis (2003)

Tajouri, Lotfi, Mellick, Albert, Ashton, Kevin John, Tannenberg, Anthony E.G., Nagra, Rashed M., Tourtellotte, Wallace W., ...

Multiple sclerosis (MS) is a complex autoimmune disorder of the CNS with both genetic and environmental contributing factors. Clinical symptoms are broadly characterized by initial onset, and...

Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis (2003)

Tajouri, Lotfi, Mellick, Albert, Ashton, Kevin John, Tannenberg, Anthony E.G., Nagra, Rashed M., Tourtellotte, Wallace W., ...

Multiple sclerosis (MS) is a complex autoimmune disorder of the CNS with both genetic and environmental contributing factors. Clinical symptoms are broadly characterized by initial onset, and...

Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis (2003)

Tajouri, Lotfi, Mellick, Albert, Ashton, Kevin John, Tannenberg, Anthony E.G., Nagra, Rashed M., Tourtellotte, Wallace W., ...

Multiple sclerosis (MS) is a complex autoimmune disorder of the CNS with both genetic and environmental contributing factors. Clinical symptoms are broadly characterized by initial onset, and...

HTLV-III: Intra-BBB IgG Synthesis and Hybridization in CSF Cells. (1998)

Tourtellotte, Wallace W.

Data has been developed indicating that antibodies specific for the AIDS virus are being synthesized within the CNS in response to the infection. About half of the AIDS and ARC patients show this....

HTLV-III: Intra-BBB IgG Synthesis and Hybridization in CSF Cells. (1998)

Tourtellotte, Wallace W.

HIV is a pathogenic retrovirus which causes a progressive deterioration of the immune system and is associated with a wide variety of human diseases. Neurological disease is a major problem in the...

T CELL SUBSETS IN MULTIPLE SCLEROSIS: GRADIENTS AT PLAQUE BORDERS AND DIFFERENCES IN NONPLAQUE REGIONS (1987)

MCCALLUM, KIMBERLI, ESIRI, MARGARET M., TOURTELLOTTE, WALLACE W., BOOSS, JOHN

This report provides a quantitative analysis of the distribution of helper-inducer T cells (H-I, LEU3A +) and cytotoxic-suppressor T cells (C-S, 0KT8 +) performed in a standardized fashion...

Enrichment of measles virus-like RNA in the nucleocapsid fraction isolated from subacute sclerosing panencephalitis brains (1982)

Bedows, Elliott, Kohne, David E., Tourtellotte, Wallace W., Payne, Francis E.

A procedure has been developed which facilitates the detection of measles virus RNA sequences in human brains. The procedure involves isolating subviral components (nucleocapsids) from brain tissues...

The importance of age effects on performance in the assessment of clinical trials (1973)

Potvin, A. R., Tourtellotte, Wallace W., Pew, Richard W., Albers, James W., Henderson, W. G., Snyder, D. N.

Forty young adult normal subjects, 10 Parkinson's disease patients and their 10 matched normal subjects, and 10 multiple sclerosis patients and their 10 matched normal subjects were evaluated in the...

A qualitative and quantitative evaluation of amantadine in the treatment of Parkinson's disease (1972)

Walker, J. E., Albers, James W., Tourtellotte, Wallace W., Henderson, W. G., Potvin, A. R., Smith, A.

A double-blind crossover trial of amantadine vs. placebo was carried out involving 42 patients with Parkinson's disease: 64 per cent of the patients on amantadine experienced subjective improvement...

On cerebrospinal fluid immunoglobulin-G (IgG) quotients in multiple sclerosis and other diseases : A review and a new formula to estimate the amount of IgG synthesized per day by the central nervous system (1970)

Tourtellotte, Wallace W.

This review of the cerebrospinal fluid (CSF) changes in multiple sclerosis has brought together relevant recent advances in CSF physiology and some aspects of the pathology of MS as they relate to...

An assessment of the reliability of three methods used in evaluating the status of multiple sclerosis patients (1969)

Kuzma, Jan W., Namerow, N. S., Tourtellotte, Wallace W., Sibley, W. A., Kurtzke, J. F., Rose, A. S., ...

The reliability of three different evaluation methods used in a cooperative clinical trial of the efficacy of ACTH in multiple sclerosis patients was evaluated in a uniformity study that used an...

Distribution of protein, lipid and administered bromide between serum and CSF in myxedema (1968)

Schacht, Richard A., Tourtellotte, Wallace W., Frame, Boy, Nickel, Stewart N.

An analysis of the blood and CSF protein concentration and lipid profiles in 14 patients with clinical myxedema has been presented. In addition, the serum and CSF bromide concentrations were measured...

Quantitative clinical neurological testing--II : Some statistical considerations of a battery of tests (1965)

Kuzma, Jan W., Tourtellotte, Wallace W., Remington, Richard D.

A battery of clinical neurological tests was evaluated statistically. In one experiment eight medical students were studied to obtain information on the reproducibility of four observers, eight...

Amyloid-β peptide–Receptor for Advanced Glycation Endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease

Du Yan, Shi, Zhu, Huaijie, Fu, Jin, Yan, Shi Fang, Roher, Alex, Tourtellotte, Wallace W., ...

In Alzheimer disease (AD), neurons are thought to be subjected to the deleterious cytotoxic effects of activated microglia. We demonstrate that binding of amyloid-beta peptide (Aβ) to neuronal...

Development and Evaluation of a Chromatographic Procedure for Partial Purification of Substance P with Quantitation by an Enzyme Immunoassay

Fehder, William P., Ho, Wen-Zhe, Campbell, Donald E., Tourtellotte, Wallace W., Michaels, Lisa, Cutilli, Joann R., ...

We have developed a simple chromatographic procedure for the partial purification of substance P (SP) from acidified plasma and serum samples. We have evaluated a sensitive antigen competition enzyme...

Amyloid-β peptide–Receptor for Advanced Glycation Endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease

Du Yan, Shi, Zhu, Huaijie, Fu, Jin, Yan, Shi Fang, Roher, Alex, Tourtellotte, Wallace W., ...

In Alzheimer disease (AD), neurons are thought to be subjected to the deleterious cytotoxic effects of activated microglia. We demonstrate that binding of amyloid-beta peptide (Aβ) to neuronal...

Development and Evaluation of a Chromatographic Procedure for Partial Purification of Substance P with Quantitation by an Enzyme Immunoassay

Fehder, William P., Ho, Wen-Zhe, Campbell, Donald E., Tourtellotte, Wallace W., Michaels, Lisa, Cutilli, Joann R., ...

We have developed a simple chromatographic procedure for the partial purification of substance P (SP) from acidified plasma and serum samples. We have evaluated a sensitive antigen competition enzyme...