Walter R. Weiss

Induction of multi-antigen multi-stage immune responses against Plasmodium falciparumin rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization (2007)

Jiang, George, Charoenvit, Yupin, Moreno, Alberto, Baraceros, Maria F, Banania, Glenna, Richie, Nancy, ...

Abstract The present study has evaluated the immunogenicity of single or multiple Plasmodium falciparum (Pf) antigens administered in a DNA prime/poxvirus boost regimen with or without the poloxamer...

Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization (2007)

Jiang, George, Charoenvit, Yupin, Moreno, Alberto, Baraceros, Maria F., Banania, Glenna, Richie, Nancy, ...

The present study has evaluated the immunogenicity of single or multiple Plasmodium falciparum (Pf) antigens administered in a DNA prime/poxvirus boost regimen with or without the poloxamer CRL1005...

Simultaneous Induction of Multiple Antigen-Specific Cytotoxic T Lymphocytes in Nonhuman Primates by Immunization with a Mixture of Four Plasmodium falciparum DNA Plasmids

Wang, Ruobing, Doolan, Denise L., Charoenvit, Yupin, Hedstrom, Richard C., Gardner, Malcolm J., Hobart, Peter, ...

CD8+ T cells have been implicated as critical effector cells in protective immunity against malaria parasites developing within hepatocytes. A vaccine that protects against malaria by inducing CD8+ T...

Protection of Rhesus Macaques against Lethal Plasmodium knowlesi Malaria by a Heterologous DNA Priming and Poxvirus Boosting Immunization Regimen

Rogers, William O., Weiss, Walter R., Kumar, Anita, Aguiar, João C., Tine, John A., Gwadz, Robert, ...

We tested a cytokine-enhanced, multiantigen, DNA priming and poxvirus boosting vaccine regimen for prevention of malaria in the Plasmodium knowlesi-rhesus macaque model system. Animals were primed...

Novel Antigen Identification Method for Discovery of Protective Malaria Antigens by Rapid Testing of DNA Vaccines Encoding Exons from the Parasite Genome

Haddad, Diana, Bilcikova, Erika, Witney, Adam A., Carlton, Jane M., White, Charles E., Blair, Peter L., ...

We describe a novel approach for identifying target antigens for preerythrocytic malaria vaccines. Our strategy is to rapidly test hundreds of DNA vaccines encoding exons from the Plasmodium yoelii...

HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

Wille-Reece, Ulrike, Flynn, Barbara J., Loré, Karin, Koup, Richard A., Kedl, Ross M., Mattapallil, Joseph J., ...

Induction and maintenance of antibody and T cell responses will be critical for developing a successful vaccine against HIV. A rational approach for generating such responses is to design vaccines or...

Simultaneous Induction of Multiple Antigen-Specific Cytotoxic T Lymphocytes in Nonhuman Primates by Immunization with a Mixture of Four Plasmodium falciparum DNA Plasmids

Wang, Ruobing, Doolan, Denise L., Charoenvit, Yupin, Hedstrom, Richard C., Gardner, Malcolm J., Hobart, Peter, ...

CD8+ T cells have been implicated as critical effector cells in protective immunity against malaria parasites developing within hepatocytes. A vaccine that protects against malaria by inducing CD8+ T...

Protection of Rhesus Macaques against Lethal Plasmodium knowlesi Malaria by a Heterologous DNA Priming and Poxvirus Boosting Immunization Regimen

Rogers, William O., Weiss, Walter R., Kumar, Anita, Aguiar, João C., Tine, John A., Gwadz, Robert, ...

We tested a cytokine-enhanced, multiantigen, DNA priming and poxvirus boosting vaccine regimen for prevention of malaria in the Plasmodium knowlesi-rhesus macaque model system. Animals were primed...

Novel Antigen Identification Method for Discovery of Protective Malaria Antigens by Rapid Testing of DNA Vaccines Encoding Exons from the Parasite Genome

Haddad, Diana, Bilcikova, Erika, Witney, Adam A., Carlton, Jane M., White, Charles E., Blair, Peter L., ...

We describe a novel approach for identifying target antigens for preerythrocytic malaria vaccines. Our strategy is to rapidly test hundreds of DNA vaccines encoding exons from the Plasmodium yoelii...

HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

Wille-Reece, Ulrike, Flynn, Barbara J., Loré, Karin, Koup, Richard A., Kedl, Ross M., Mattapallil, Joseph J., ...

Induction and maintenance of antibody and T cell responses will be critical for developing a successful vaccine against HIV. A rational approach for generating such responses is to design vaccines or...

Protection of Rhesus Monkeys by a DNA Prime/Poxvirus Boost Malaria Vaccine Depends on Optimal DNA Priming and Inclusion of Blood Stage Antigens

Weiss, Walter R., Kumar, Anita, Jiang, George, Williams, Jackie, Bostick, Anthony, Conteh, Solomon, ...

Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

Wille-Reece, Ulrike, Flynn, Barbara J., Loré, Karin, Koup, Richard A., Miles, Aaron P., Saul, Allan, ...

There is a remarkable heterogeneity in the functional profile (quality) of T cell responses. Importantly, the magnitude and/or quality of a response required for protection may be different depending...

Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization

Jiang, George, Charoenvit, Yupin, Moreno, Alberto, Baraceros, Maria F, Banania, Glenna, Richie, Nancy, ...

The present study has evaluated the immunogenicity of single or multiple Plasmodium falciparum (Pf) antigens administered in a DNA prime/poxvirus boost regimen with or without the poloxamer CRL1005...

Sterile Protection against Plasmodium knowlesi in Rhesus Monkeys from a Malaria Vaccine: Comparison of Heterologous Prime Boost Strategies

Jiang, George, Shi, Meng, Conteh, Solomon, Richie, Nancy, Banania, Glenna, Geneshan, Harini, ...

Using newer vaccine platforms which have been effective against malaria in rodent models, we tested five immunization regimens against Plasmodium knowlesi in rhesus monkeys. All vaccines included the...