Sahoo, Nivedita, Beatty, Wandy, Heuser, John, Sept, David, Sibley, L. David
Toxoplasma is a protozoan parasite in the phylum Apicomplexa, which contains a number of medically important parasites that rely on a highly unusual form of motility termed gliding to actively...
Banerjee, Ritu, Liu, Jun, Beatty, Wandy, Pelosof, Lorraine, Klemba, Michael, Goldberg, Daniel E.
Hemoglobin degradation is a metabolic process that is central to the growth and maturation of the malaria parasite Plasmodium falciparum. Two aspartic proteases that initiate degradation, plasmepsins...
Banerjee, Ritu, Liu, Jun, Beatty, Wandy, Pelosof, Lorraine, Klemba, Michael, Goldberg, Daniel E.
Hemoglobin degradation is a metabolic process that is central to the growth and maturation of the malaria parasite Plasmodium falciparum. Two aspartic proteases that initiate degradation, plasmepsins...
Sahoo, Nivedita, Beatty, Wandy, Heuser, John, Sept, David, Sibley, L. David
Toxoplasma is a protozoan parasite in the phylum Apicomplexa, which contains a number of medically important parasites that rely on a highly unusual form of motility termed gliding to actively...
Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum
Klemba, Michael, Beatty, Wandy, Gluzman, Ilya, Goldberg, Daniel E.
fA amily of aspartic proteases, the plasmepsins (PMs), plays a key role in the degradation of hemoglobin in the Plasmodium falciparum food vacuole. To study the trafficking of proPM II, we have...
HDP—A Novel Heme Detoxification Protein from the Malaria Parasite
Jani, Dewal, Nagarkatti, Rana, Beatty, Wandy, Angel, Ross, Slebodnick, Carla, Andersen, John, ...
When malaria parasites infect host red blood cells (RBC) and proteolyze hemoglobin, a unique, albeit poorly understood parasite-specific mechanism, detoxifies released heme into hemozoin (Hz). Here,...