Fang Weiyi, Li Xin, Jiang Qingping, Liu Zhen, Yang Huiling, Wang Shuang, ...
Abstract Background The pathogenesis of nasopharyngeal carcinoma (NPC) is a complicated process involving genetic predisposition, Epstein-Bar Virus infection, and genetic alterations. Although some...
Combining identity by descent and association in genetic case-control studies (2008)
Zhang Qingrun, Wang Shuang, Ott Jurg
Abstract Background In human case-control association studies, one of the chi-square tests typically carried out is based on a 2 × 3 table of genotypes (homogeneity of three genotype frequencies...
Luo Xingguang, Zuo Lingjun, Kranzler Henry, Wang Shuang, Anton Raymond, Gelernter Joel
Abstract Background In our previous studies, we reported positive associations between seven ADH4 polymorphisms and substance dependence [i.e., alcohol dependence (AD) and/or drug dependence (DD)] in...
Xie Si, Fang Wei, Liu Zhen, Wang Shuang, Li Xin, Liu Teng, ...
Abstract Background High resistance to drug is taken as a characteristic of human tumors, which is usually mediated by multidrug resistance-associated genes. ABCC2, an ATP-binding cassette multidrug...
Shuang, Wang, Shuang-Qing, Wu, Fei, Xie, Lin, Dan
We investigate the first law of thermodynamics in the case of the (2+1)-dimensional BTZ black holes and Kerr-de Sitter spacetimes, in particular, we focus on the integral mass formulas. It is found...
Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene (2006)
Nakamoto Kaori, Wang Shuang, Jenison Robert, Guo Grace, Klaassen Curtis, Wan Yu-Jui, ...
Abstract Background Cholesterol 7-alpha-hydroxylase (CYP7A1) is the rate limiting enzyme for converting cholesterol into bile acids. Genetic variations in the CYP7A1 gene have been associated with...
Oh Cheongeun, Wang Shuang, Liu Nianjun, Chen Liang, Zhao Hongyu
Abstract Common human disorders, such as alcoholism, may be the result of interactions of many genes as well as environmental risk factors. Therefore, it is important to incorporate gene × gene and...
Chen Liang, Liu Nianjun, Wang Shuang, Oh Cheongeun, Carriero Nicholas, Zhao Hongyu
Abstract Alcoholism is a complex disease. As with other common diseases, genetic variants underlying alcoholism have been illusive, possibly due to the small effect from each individual susceptible...
Liu Nianjun, Chen Liang, Wang Shuang, Oh Cheongeun, Zhao Hongyu
Abstract Single-nucleotide polymorphisms (SNPs) are a class of attractive genetic markers for population genetic studies and for identifying genetic variations underlying complex traits. However, the...
Wang Shuang, Huang Song, Liu Nianjun, Chen Liang, Oh Cheongeun, Zhao Hongyu
Abstract There is currently a great interest in using single-nucleotide polymorphisms (SNPs) in genetic linkage and association studies because of the abundance of SNPs as well as the availability of...
Huang Song, Wang Shuang, Liu Nianjun, Chen Liang, Oh Cheongeun, Zhao Hongyu
Abstract Recombination during meiosis is one of the most important biological processes, and the level of recombination rates for a given individual is under genetic control. In this study, we...
Zheng Liangbiao, Wang Shuang, Romans Patricia, Zhao Hongyu, Luna Coralia, Benedict Mark
Abstract Background Anopheles gambiae females are the world's most successful vectors of human malaria. However, a fraction of these mosquitoes is refractory to Plasmodium development. L3-5, a...