A flexible two-stage procedure for identifying gene sets that are differentially expressed (2009)
Heller, Ruth, Manduchi, Elisabetta, Grant, Gregory R., Ewens, Warren J.
Motivation: Microarray data analysis has expanded from testing individual genes for differential expression to testing gene sets for differential expression. The tests at the gene set level may focus...
Ewens, Warren J., Wilf, Herbert S.
We present a rapid method for the exact calculation of the cumulative distribution function of the maximum of multinomially distributed random variables. The method runs in time $O(mn)$, where $m$ is...
Heterozygous carriers of Nijmegen Breakage Syndrome have a distinct gene expression phenotype (2006)
Cheung, Vivian G., Ewens, Warren J.
Autosomal recessive diseases are those that require mutations in both alleles to exhibit the disorder. Although most recessive conditions are rare, heterozygous carriers of recessive mutations are...
Heterozygous carriers of Nijmegen Breakage Syndrome have a distinct gene expression phenotype (2006)
Cheung, Vivian G., Ewens, Warren J.
Autosomal recessive diseases are those that require mutations in both alleles to exhibit the disorder. Although most recessive conditions are rare, heterozygous carriers of recessive mutations are...
Properties of Equilibria in Multi-Locus Genetic Systems
Ewens, Warren J., Thomson, Glenys
The classical mathematical theory of population genetics considered, for simplicity, almost exclusively one-locus systems. In the last two decades much work has been done on two-locus and, less...
Gene Expression Phenotype in Heterozygous Carriers of Ataxia Telangiectasia
Watts, Jason A., Morley, Michael, Burdick, Joshua T., Fiori, Jennifer L., Ewens, Warren J., Spielman, Richard S., ...
The defining characteristic of recessive diseases is the absence of a phenotype in the heterozygous carriers. Nonetheless, subtle manifestations may be detectable by new methods, such as expression...
Properties of Equilibria in Multi-Locus Genetic Systems
Ewens, Warren J., Thomson, Glenys
The classical mathematical theory of population genetics considered, for simplicity, almost exclusively one-locus systems. In the last two decades much work has been done on two-locus and, less...
Heterozygous carriers of Nijmegen Breakage Syndrome have a distinct gene expression phenotype
Cheung, Vivian G., Ewens, Warren J.
Autosomal recessive diseases are those that require mutations in both alleles to exhibit the disorder. Although most recessive conditions are rare, heterozygous carriers of recessive mutations are...
Ewens, Warren J., Wilf, Herbert S.
We present a rapid method for the exact calculation of the cumulative distribution function of the maximum of multinomially distributed random variables. The method runs in time O(mn), where m is the...
Ewens, Warren J., Li, Mingyao, Spielman, Richard S.
Quantitative trait transmission/disequilibrium tests (quantitative TDTs) are commonly used in family-based genetic association studies of quantitative traits. Despite the availability of various...