Weiguo Zhao

Malnutrition Alters the Innate Immune Response and Increases Early Visceralization following Leishmania donovani Infection

Anstead, Gregory M., Chandrasekar, Bysani, Zhao, Weiguo, Yang, Jue, Perez, Luis E., Melby, Peter C.

Malnutrition is a risk factor for the development of visceral leishmaniasis. However, the immunological basis for this susceptibility is unknown. We have developed a mouse model to study the effect...

Leishmania donovani p36(LACK) DNA Vaccine Is Highly Immunogenic but Not Protective against Experimental Visceral Leishmaniasis

Melby, Peter C., Yang, Jue, Zhao, Weiguo, Perez, Luis E., Cheng, Jun

The acquisition of immunity following subclinical or resolved infection with the intracellular parasite Leishmania donovani suggests that vaccination could prevent visceral leishmaniasis (VL). The...

Identification of Vaccine Candidates for Experimental Visceral Leishmaniasis by Immunization with Sequential Fractions of a cDNA Expression Library

Melby, Peter C., Ogden, Gary B., Flores, Hector A., Zhao, Weiguo, Geldmacher, Christopher, Biediger, Natalie M., ...

Visceral leishmaniasis caused by the intracellular parasite Leishmania donovani is a significant public health problem in many regions of the world. Because of its large genome and complex biology,...

Regional Differences in the Cellular Immune Response to Experimental Cutaneous or Visceral Infection with Leishmania donovani

Melby, Peter C., Yang, Yan-Zhu, Cheng, Jun, Zhao, Weiguo

Infection with the protozoan Leishmania donovani can cause serious visceral disease or subclinical infection in humans. To better understand the pathogenesis of this dichotomy, we have investigated...

Malnutrition Alters the Innate Immune Response and Increases Early Visceralization following Leishmania donovani Infection

Anstead, Gregory M., Chandrasekar, Bysani, Zhao, Weiguo, Yang, Jue, Perez, Luis E., Melby, Peter C.

Malnutrition is a risk factor for the development of visceral leishmaniasis. However, the immunological basis for this susceptibility is unknown. We have developed a mouse model to study the effect...

Leishmania donovani p36(LACK) DNA Vaccine Is Highly Immunogenic but Not Protective against Experimental Visceral Leishmaniasis

Melby, Peter C., Yang, Jue, Zhao, Weiguo, Perez, Luis E., Cheng, Jun

The acquisition of immunity following subclinical or resolved infection with the intracellular parasite Leishmania donovani suggests that vaccination could prevent visceral leishmaniasis (VL). The...

Identification of Vaccine Candidates for Experimental Visceral Leishmaniasis by Immunization with Sequential Fractions of a cDNA Expression Library

Melby, Peter C., Ogden, Gary B., Flores, Hector A., Zhao, Weiguo, Geldmacher, Christopher, Biediger, Natalie M., ...

Visceral leishmaniasis caused by the intracellular parasite Leishmania donovani is a significant public health problem in many regions of the world. Because of its large genome and complex biology,...

Regional Differences in the Cellular Immune Response to Experimental Cutaneous or Visceral Infection with Leishmania donovani

Melby, Peter C., Yang, Yan-Zhu, Cheng, Jun, Zhao, Weiguo

Infection with the protozoan Leishmania donovani can cause serious visceral disease or subclinical infection in humans. To better understand the pathogenesis of this dichotomy, we have investigated...