Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS study (2007)
Mitrou, Panagiota N.,
Watson, Mark A.,
Loktionov, Alexandre S.,
Cardwell, Christopher,
Gunter, Marc J.,
Atkin, Wendy S.,
...
NADP(H):quinone oxidoreductase 1 (NQO1) and microsomal epoxide hydrolase (EPHX1, also mEH) are attractive candidate enzymes for association with colorectal neoplasia because they metabolize a number...
MTHFR (C677T and A1298C) polymorphisms and risk of sporadic distal colorectal adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom) (2006)
Mitrou, Panagiota N.,
Watson, Mark A.,
Loktionov, Alexandre S.,
Cardwell, Christopher,
Gunter, Marc J.,
Atkin, Wendy S.,
...
Objective The purpose of this study was to further evaluate the role of low activity MTHFR variants as well as to explore interactive effects between alcoholic drink consumption and MTHFR variants...
No association between cytochrome P450 and glutathione S-transferase gene polymorphisms and risk of colorectal adenoma: results from the UK Flexible Sigmoidoscopy Screening Trial (2005)
Gunter, Marc J.,
Watson, Mark A.,
Loktionov, Alexandre S.,
Mitrou, Panagiota,
Cecil, Tom,
Macklin, Christopher,
...
INTRODUCTION Genetic variation in carcinogen metabolizing enzymes has been proposed as a susceptibility marker for colorectal neoplasia. The cytochrome P450 (CYP) and glutathione S-transferase (GST)...
Single blind, randomised trial of efficacy and acceptability of oral Picolax versus self administered phosphate enema in bowel preparation for flexible sigmoidoscopy screening
Atkin, Wendy S,
Hart, Andrew,
Edwards, Robert,
Cook, Claire F,
Wardle, Jane,
McIntyre, Peter,
...
Single blind, randomised trial of efficacy and acceptability of oral Picolax versus self administered phosphate enema in bowel preparation for flexible sigmoidoscopy screening
Atkin, Wendy S,
Hart, Andrew,
Edwards, Robert,
Cook, Claire F,
Wardle, Jane,
McIntyre, Peter,
...