Design and synthesis of novel beta-lactam antibiotics (2001)
ò-Lactam antibiotics are the dominant class of antibiotics used today. They exert their antibacterial activity by inhibiting a class of enzymes called penicillin binding proteins (PBPs)....
A 1.2-Å snapshot of the final step of bacterial cell wall biosynthesis
Lee, Wenlin, McDonough, Michael A., Kotra, Lakshmi P., Li, Zhi-Hong, Silvaggi, Nicholas R., Takeda, Yoshifumi, ...
The cell wall imparts structural strength and shape to bacteria. It is made up of polymeric glycan chains with peptide branches that are cross-linked to form the cell wall. The cross-linking...
A 1.2-Å snapshot of the final step of bacterial cell wall biosynthesis
Lee, Wenlin, McDonough, Michael A., Kotra, Lakshmi P., Li, Zhi-Hong, Silvaggi, Nicholas R., Takeda, Yoshifumi, ...
The cell wall imparts structural strength and shape to bacteria. It is made up of polymeric glycan chains with peptide branches that are cross-linked to form the cell wall. The cross-linking...