Werner Müller

VBASE2, an integrative V gene database (2005)

Retter, Ida, Althaus, Hans Helmar, Münch, Richard, Müller, Werner

The database VBASE2 provides germ-line sequences of human and mouse immunoglobulin variable (V) genes. It acts as an interconnecting platform between several existing self-contained data systems:...

The European dimension for the mouse genome mutagenesis program. (2004)

Auwerx, Johan, Avner, Phil, Baldock, Richard, Ballabio, Andrea, Balling, Rudi, Barbacid, Mariano, ...

The European Mouse Mutagenesis Consortium is the European initiative contributing to the international effort on functional annotation of the mouse genome. Its objectives are to establish and...

Die Qualität biologisch erzeugter Lebensmittel. Umfassende Literaturrecherche zur Ermittlung potenzieller Vorteile biologisch erzeugter Lebensmittel (2003)

Velimirov, Alberta, Müller, Werner

Die Studie fasst die Ergenisse von 175 Forschungsarbeiten zum Thema Lebensmittelqualiät und ökologischer Landbau zusammen. 1. Überblick Lebensmittel und Landwirtschaft und Gesundheit 1.1...

Biologischer Obstbau auf Hochstämmen (2003)

Häseli, Andreas, Weibel, Franco, Brunner, Hans, Müller, Werner, Kranzler, Andreas, Spornberger, Andreas, ...

Das Merkblatt vermittelt Praktikerinnen und Praktikern alle Informationen, die sie für eine erfolgreiche, ökologisch und wirtschaftlich abgestimmte Produktion von biologischem Verarbeitungs- und...

Regional convergence in the European Union (1985-1999) (2002)

Badinger, Harald, Müller, Werner, Tondl, Gabriele

We estimate the speed of income convergence for a sample of 196 European NUTS 2 regions over the period 1985-1999. So far there is no direct estimator available for dynamic panels with strong spatial...

Optimal Design of Experiments Subject to Correlated Errors (2000)

Pazman, Andrej, Müller, Werner

In this paper we consider optimal design of experiments in the case of correlated observations, when no replications are possible. This situation is typical when observing a random process or random...

A Panel Data Analysis: Research & Development Spillover (1998)

Müller, Werner, Nettekoven, Michaela

Panel data analysis has become an important tool in applied econometrics and the respective statistical techniques are well described in several recent textbooks. However, for an analyst using these...

Optimal Design for Variogram Estimation (1997)

Müller, Werner, Zimmerman, Dale L.

The variogram plays a central role in the analysis of geostatistical data. A valid variogram model is selected and the parameters of that model are estimated before kriging (spatial prediction) is...

IMGT, the international ImMunoGeneTics database (1997)

Véronique Giudicelli, Denys Chaume, Julia Bodmer, Werner Müller, Chantal Busin, Steven Marsh, ...

IMGT, the international ImMunoGeneTics database, is an integrated database specializing in immunoglobulins, T-cell receptors (TcR) and major histocompatibility complex (MHC) of all vertebrate...

Extended Information Matrices for Optimal Designs when the Observations are Correlated II (1996)

Pazman, Andrej, Müller, Werner

Regression models with correlated errors lead to nonadditivity of the information matrix. This makes the usual approach of design optimization (approximation with a continuous design, application of...

Extended Information Matrices for Optimal Designs when the Observations are Correlated (1996)

Pazman, Andrej, Müller, Werner

Regression models with correlated errors lead to nonadditivity of the information matrix. This makes the usual approach of design optimization (approximation with a continuous design, application of...

Comparing Local Fitting to Other Automatic Smoothers (1995)

Maderbacher, Michael, Müller, Werner

In a public service enterprise by Breiman and Peters (1991) various automatic smoothers, such as the supersmoother (SSMU), cross-validated smoothing splines (BART), delete-knot regression splines...

Optimal Design of an Experiment in Economics (1993)

Müller, Werner

This paper deals with the application of optimal design principles in an experiment examining individual decision making under risk. It provides general principles on how to conduct experiments in a...

Discrimination Between Two Binary Data Models (1993)

Müller, Werner, Ponce De Leon, Antonio C.

In this paper we describe and illustrate a sequential approach for the problem of designing experiments to discriminate between binary data models as efficiently as possible. The models considered...

Moving Local Regression: The Weight Function (1992)

Fedorov, Valery V., Hackl, Peter, Müller, Werner

Moving local regression is a nonparametric technique for smoothing, interpolating and forecasting by means of locally fitted regression models. The paper explores the "optimal" structure of the...

Optimal Design for Moving Local Regressions (1992)

Müller, Werner

This paper describes the so-called moving local regression, a special nonparametric statistical tool, which is firstly discussed thoroughly from analysis point of view. It avoids some drawbacks of...

Forecasting with Optimized Moving Local Regression (1992)

Fedorov, Valery V., Hackl, Peter, Müller, Werner

This paper empirically demonstrates the relative merits of the optimal choice of the weight function in a moving local regression as suggested by Fedorov et al., (1993) over traditional weight...

Optimal and Practicable Designs for Measuring Plaque pH-Profiles (1991)

Fedorov, Valery V., Hackl, Peter, Müller, Werner

In this paper we will show that the theory of optimal experimental design leads to quite different patterns of measurement. These patterns take into account (a) the structure of the ongoing process...

Estimation and Experimental Design for Second Kind Regression Models (1990)

Fedorov, Valery V., Hackl, Peter, Müller, Werner

Estimation procedures and optimal designs for estimation of the individual parameters and of the global parameters are discussed under various conditions of prior knowledge. The extension to...

Polyethylene glycol derivatives of base and sequence specific DNA ligands: DNA interaction and application for base specific separation of DNA fragments by gel electrophoresis (1981)

Müller, Werner, Hattesohl, Iolanda, Schuetz, Hans-Jürgen, Meyer, Georg

Various base pair specific DNA ligands comprising a phenyl phenazinium dye, a triphenylmethan dye and Hoechst 33258 were covalently bound to polyethylene glycol (PEG) via ester or ether bonds. The...

Size fractionation of DNA fragments by liquid-liquid chromatography (1979)

Müller, Werner, Schuetz, Hans-Jügen, Guerrier-Takada, Cecilia, Cole, Patricia E., Potts, Russell

A method for the fractionation of double-stranded DNA fragments from 150 to 22000 b.p. in size by liquid-liquid chromatography is described. The procedure makes use of the fact that the partitioning...

Base specific fractionation of double stranded DNA: affinity chromatography on a novel type of adsorbant (1978)

Bünemann, Hans, Müller, Werner

A material suitable for base-pair-specific ‘affinity chromatography’ of double stranded DNA is described. The synthesis of this material involves two successive polymerization reactions yielding...

Regional Convergence in the European Union, 1985- 1999: A Spatial Dynamic Panel Analysis

Harald Badinger, Werner Müller, Gabriele Tondl

Badinger H., Müller W. G. and Tondl G. (2004) Regional convergence in the European Union, 1985- 1999: a spatial dynamic panel analysis, Reg. Studies 38 , 241-253. We estimate the speed of income...

Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man

Luchtefeld, Maren, Schunkert, Heribert, Stoll, Monika, Selle, Tina, Lorier, Rachel, Grote, Karsten, ...

Liver-derived acute phase proteins (APPs) emerged as powerful predictors of cardiovascular disease and cardiovascular events, but their functional role in atherosclerosis remains enigmatic. We report...

T Cell–specific Inactivation of the Interleukin 10 Gene in Mice Results in Enhanced T Cell Responses but Normal Innate Responses to Lipopolysaccharide or Skin Irritation

Roers, Axel, Siewe, Lisa, Strittmatter, Elke, Deckert, Martina, Schlüter, Dirk, Stenzel, Werner, ...

Interleukin (IL)-10 is a regulator of inflammatory responses and is secreted by a variety of different cell types including T cells. T regulatory cells have been shown to suppress immune responses by...

Mast cell-specific Cre/loxP-mediated recombination in vivo

Scholten, Julia, Hartmann, Karin, Gerbaulet, Alexander, Krieg, Thomas, Müller, Werner, Testa, Giuseppe, ...

Mast cells are important effectors of type I allergy but also essential regulators of innate and adaptive immune responses. The aim of this study was to develop a Cre recombinase-expressing mouse...

Rearrangement and Expression of Immunoglobulin Light Chain Genes Can Precede Heavy Chain Expression during Normal B Cell Development in Mice

Novobrantseva, Tatiana I., Martin, Verena M., Pelanda, Roberta, Müller, Werner, Rajewsky, Klaus, Ehlich, Andreas

In mouse mutants incapable of expressing μ chains, VκJκ joints are detected in the CD43+ B cell progenitors. In agreement with these earlier results, we show by a molecular single cell analysis...

Neonatally Induced Inactivation of the Vascular Cell Adhesion Molecule 1 Gene Impairs B Cell Localization and T Cell–Dependent Humoral Immune Response

Leuker, Christoph E., Labow, Mark, Müller, Werner, Wagner, Norbert

Vascular cellular adhesion molecule (VCAM)-1 is a membrane-bound cellular adhesion molecule that mediates adhesive interactions between hematopoietic progenitor cells and stromal cells in the bone...

Interleukin-4 Protects against a Genetically Linked Lupus-like Autoimmune Syndrome

Santiago, Marie-Laure, Fossati, Liliane, Jacquet, Chantal, Müller, Werner, Izui, Shozo, Reininger, Luc

Interleukin-4 (IL-4) provides support for humoral immune responses through upregulation of T helper (Th) type 2 cell differentiation, but it is not known whether IL-4 promotes antibodymediated...

Postnatally Induced Inactivation of gp130 in Mice Results in Neurological, Cardiac, Hematopoietic, Immunological, Hepatic, and Pulmonary Defects

Betz, Ulrich A.K., Bloch, Wilhelm, Van Den Broek, Maries, Yoshida, Kanji, Taga, Tetsuya, Kishimoto, Tadamitsu, ...

The pleiotrophic but overlapping functions of the cytokine family that includes interleukin (IL)-6, IL-11, leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, and cardiotrophin 1...

Regional convergence in the European Union (1985-1999). A spatial dynamic panel analysis

Gabriele Tondl, Harald Badinger, Werner Müller

We estimate the speed of income convergence for a sample of 196 European NUTS 2 regions over the period 1985-1999. So far there is no direct estimator available for dynamic panels with strong spatial...

GP130-STAT3 Regulates Epithelial Cell Migration and Is Required for Repair of the Bronchiolar Epithelium

Kida, Hiroshi, Mucenski, Michael L., Thitoff, Angela R., Le Cras, Timothy D., Park, Kwon-Sik, Ikegami, Machiko, ...

Following injury, bronchiolar cells undergo rapid squamous metaplasia, followed by proliferation and re-establishment of the complex columnar epithelium that is characteristic of the normal airway....

More on the distribution of the sum of uniform random variables

Heinrich Potuschak, Werner Müller

Uniform distribution, Inverse fourier transform, Normal approximation,

Basel II: Führen die neuen Anforderungen an die Kreditinstitute zu einer Benachteiligung des Mittelstands?

Werner Müller, Helmut Krämer-Eis, Gregor Taistra, Gerhard Hofmann, Thomas Heidorn, Stephan Paul, ...

In der Öffentlichkeit wurden Befürchtungen geäußert, dass Basel II den Mittelstand benachteilige, indem die Kreditverfügbarkeit für die Unternehmen eingeschränkt und ihre Zinskosten steigen...

Deutschland: In der Weltwirtschaft wieder auf der Überholspur!

Werner Müller

In seinem Vortrag auf der 53. ifo Jahresversammlung stellt Bundeswirtschaftsminister Dr. Werner Müller die positive Entwicklung der Wirtschaftsdaten in Deutschland heraus. Er hebt die guten...