Wesley C. Warren

Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals (2008)

Patel, Vidushi S, Cooper, Steven JB, Deakin, Janine E, Fulton, Bob, Graves, Tina, Warren, Wesley C, ...

Abstract Background Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin...

Loss of genes implicated in gastric function during platypus evolution (2008)

Ordoñez, Gonzalo R, Hillier, LaDeana W, Warren, Wesley C, Grützner, Frank, López-Otín, Carlos, Puente, Xose S

Abstract Background The duck-billed platypus ( Ornithorhynchus anatinus ) belongs to the mammalian subclass Prototheria, which diverged from the Theria line early in mammalian evolution. The platypus...

Genome analysis of the platypus reveals unique signatures of evolution (2008)

Warren, Wesley C., Hillier, LaDeana W., Marshall Graves, Jennifer A., Birney, Ewan, Ponting, Chris P., Grützner, Frank, ...

We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a...

Physical map-assisted whole-genome shotgun sequence assemblies (2006)

Warren, René L., Varabei, Dmitry, Platt, Darren, Huang, Xiaoqiu, Messina, David, Yang, Shiaw-Pyng, ...

We describe a targeted approach to improve the contiguity of whole-genome shotgun sequence (WGS) assemblies at run-time, using information from Bacterial Artificial Chromosome (BAC)-based physical...

A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms (2004)

Liu, Bin, Wang, Jun, Zhang, Yong, Yang, Xu, Zhang, Zengjin, ...

We describe a genetic variation map for the chicken genome containing 2.8 million single-nucleotide polymorphisms (SNPs). This map is based on a comparison of the sequences of three domestic chicken...

A physical map of the chicken genome (2004)

Wallis, John W, Aerts, Jan, Groenen, Martien A M, Layman, Dan, Graves, Tina A, ...

Strategies for assembling large, complex genomes have evolved to include a combination of whole-genome shotgun sequencing and hierarchal map-assisted sequencing. Whole-genome maps of all types can...

Fosmid-Based Physical Mapping of the Histoplasma capsulatum Genome (2004)

Magrini, Vincent, Warren, Wesley C., Wallis, John, Goldman, William E., Xu, Jian, Mardis, Elaine R., ...

A fosmid library representing 10-fold coverage of the Histoplasma capsulatum G217B genome was used to construct a restriction-based physical map. The data obtained from three restriction endonuclease...

Fosmid-Based Physical Mapping of the Histoplasma capsulatum Genome

Magrini, Vincent, Warren, Wesley C., Wallis, John, Goldman, William E., Xu, Jian, Mardis, Elaine R., ...

A fosmid library representing 10-fold coverage of the Histoplasma capsulatum G217B genome was used to construct a restriction-based physical map. The data obtained from three restriction endonuclease...

Physical map-assisted whole-genome shotgun sequence assemblies

Warren, René L., Varabei, Dmitry, Platt, Darren, Huang, Xiaoqiu, Messina, David, Yang, Shiaw-Pyng, ...

We describe a targeted approach to improve the contiguity of whole-genome shotgun sequence (WGS) assemblies at run-time, using information from Bacterial Artificial Chromosome (BAC)-based physical...

Fosmid-Based Physical Mapping of the Histoplasma capsulatum Genome

Magrini, Vincent, Warren, Wesley C., Wallis, John, Goldman, William E., Xu, Jian, Mardis, Elaine R., ...

A fosmid library representing 10-fold coverage of the Histoplasma capsulatum G217B genome was used to construct a restriction-based physical map. The data obtained from three restriction endonuclease...

Physical map-assisted whole-genome shotgun sequence assemblies

Warren, René L., Varabei, Dmitry, Platt, Darren, Huang, Xiaoqiu, Messina, David, Yang, Shiaw-Pyng, ...

We describe a targeted approach to improve the contiguity of whole-genome shotgun sequence (WGS) assemblies at run-time, using information from Bacterial Artificial Chromosome (BAC)-based physical...

Loss of genes implicated in gastric function during platypus evolution

Ordoñez, Gonzalo R, Hillier, LaDeana W, Warren, Wesley C, Grützner, Frank, López-Otín, Carlos, Puente, Xose S

Several genes implicated in food digestion have been deleted or inactivated in platypus. This loss perhaps explains the anatomical and physiological differences in the gastrointestinal tract between...

Defensins and the convergent evolution of platypus and reptile venom genes

Whittington, Camilla M., Papenfuss, Anthony T., Bansal, Paramjit, Torres, Allan M., Wong, Emily S.W., Deakin, Janine E., ...

When the platypus (Ornithorhynchus anatinus) was first discovered, it was thought to be a taxidermist’s hoax, as it has a blend of mammalian and reptilian features. It is a most remarkable mammal,...